Administration of Oral Acetaminophen to Reduce Costs for the Hysterectomy Patient at a Community Hospital

Blonk, Kristin M.; Davenport, Ashley; Morgan, Brett; Muckler, Virginia C.

doi:10.1016/j.jopan.2018.03.007

Cited by 3 publications

(2 citation statements)

References 9 publications

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“…A further 13 were excluded after full text analysis. Nine studies were therefore identified for inclusion in this analysis (Blonk et al 2019, Fenlon et al 2013, Hickman et al 2018, Johnson et al 2019, Lombardi et al 2019, Mahajan et al 2017, Patel et al 2020, Plunkett et al 2017, Yu et al 2020). The studies were published between 2013 and 2020.…”

Section: Resultsmentioning

confidence: 99%

“…However, the strength of the results is limited by the quality of the included studies. Only five of the studies were randomised controlled trials (Fenlon et al 2013, Hickman et al 2018, Lombardi et al 2019, Patel et al 2020, Plunkett et al 2017 with several others being retrospective in nature (Blonk et al 2019, Johnson et al 2019, Mahajan et al 2017, Yu 2020. Nearly half of the included studies had small sample sizes of 100 or fewer participants, and some studies had a lack of blinding, both to patients and to staff, which introduces significant potential for bias.…”

Section: Discussionmentioning

confidence: 99%

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Intravenous versus oral paracetamol for postoperative analgesia: A systematic review

Stagg

2020

Journal of Perioperative Practice

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Paracetamol is a widely used analgesic agent that can be given by several different routes of administration. In the surgical setting, intravenous infusions of paracetamol are used, but an alternative is using oral paracetamol as a premedication. This systematic review is the first to compare the relative efficacy of intravenous and oral paracetamol at providing postoperative analgesia. Nine relevant studies were identified. Intravenous paracetamol resulted in a postoperative pain score of 0.5 points lower than in those receiving oral paracetamol premedication. Patients receiving intravenous paracetamol also had a small reduction in postoperative opioid requirements, but the time at which rescue analgesia was required did not differ. These results suggest that intravenous paracetamol may offer a small advantage over oral paracetamol premedication at providing postoperative analgesia.

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