Adjustment in Parents of Children Undergoing Stem Cell Transplantation

Lindwall, Jennifer; Russell, Kathy; Huang, Qiuqiong; Zhang, Hui; Vannatta, Kathryn; Barrera, Maru; Alderfer, Melissa A.; Phipps, Sean

doi:10.1016/j.bbmt.2014.01.007

Cited by 28 publications

(49 citation statements)

References 32 publications

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“…This is in line with recent qualitative research conducted with fathers of youth with chronic pain 12 . Optimism and benefit finding as resilience-based factors have been hypothesized to be protective leading to better coping with chronic pain 13 and other pediatric chronic illnesses 38 . In addition to constructs such as parent acceptance and psychological flexibility, optimism and benefit finding warrant further consideration in pediatric pain research.…”

Section: Discussionmentioning

confidence: 99%

Characterizing the Pain Narratives of Parents of Youth With Chronic Pain

Noel

Beals-Erickson²,

Law

et al. 2016

The Clinical Journal of Pain

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Objectives Questionnaire-based research has shown that parents exert a powerful influence on and are profoundly influenced by living with a child with chronic pain. Examination of parents' pain narratives through an observational lens offers an alternative approach to understanding the complexity of pediatric chronic pain; however, the narratives of parents of youth with chronic pain have been largely overlooked. The present study aimed to characterize the vulnerability- and resilience-based aspects of the pain narratives of parents of youth with chronic pain. Methods Pain narratives of 46 parents were recorded during the baseline session as part of two clinical trials evaluating a behavioral intervention for parents of youth with chronic pain. The narratives were coded for aspects of pain-related vulnerability and resilience. Results Using exploratory cluster analysis, two styles of parents’ pain narratives were identified. Distress narratives were characterized by more negative affect and an exclusively unresolved orientation towards the child’s diagnosis of chronic pain whereas resilience narratives were characterized by positive affect and a predominantly resolved orientation towards the child’s diagnosis. Preliminary support for the validity of these clusters was provided through our finding of differences between clusters in parental pain catastrophizing about child pain (helplessness). Discussion Findings highlight the multidimensional nature of parents’ experience of their child’s pain problem. Clinical implications in terms of assessment and treatment are discussed.

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Section: Discussionmentioning

confidence: 99%

Characterizing the Pain Narratives of Parents of Youth With Chronic Pain

Noel

Beals-Erickson²,

Law

et al. 2016

The Clinical Journal of Pain

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“…To date, most of the psychological interventions developed have focused on caregivers of children with cancer (Mullins et al, 2012; Sahler et al, 2013). There has been one randomized clinical trial (Lindwall et al, 2014), which evaluated the efficacy of a child and parent massage and humor therapy intervention. Parents were randomly assigned to receive a child-targeted massage and humor therapy intervention; the child intervention, a parent-targeted massage, and humor therapy intervention; or standard care.…”

Section: Caregiver Distress and Psychological Interventions Targetingmentioning

confidence: 99%

“…Traumatic distress was included as a primary outcome due to the prevalence of traumatic stress responses in this population (see Packman et al, 2010, for a review of this topic). Positive well-being was evaluated as a secondary outcome because positive outcomes are an important component of the caregiving experience and behavioral interventions for parent caregivers have assessed positive well-being as an indicator of treatment response (Lindwall et al, 2014) Because P-SCIP targeted coping skills that to be used to manage stressors experienced during the year after HSCT, we proposed that the beneficial effects of P-SCIP would have a persistent effect over the one year post-HSCT that caregivers were evaluated.…”

Section: Study Aimsmentioning

confidence: 99%

A randomized clinical trial of a parent-focused social-cognitive processing intervention for caregivers of children undergoing hematopoetic stem cell transplantation.

Manne

Mee²,

Bartell

et al. 2016

Journal of Consulting and Clinical Psychology

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Objective Providing care to one’s child during and after a hematopoietic stem cell transplant (HSCT) is a universally stressful experience, but few psychological interventions have been developed to reduce caregiver distress. The goal of this study was to test the efficacy of a brief cognitive–behavioral intervention delivered to primary caregivers. Method Two hundred eighteen caregivers were assigned either best-practice psychosocial care (BPC) or a parent social-cognitive intervention program (P-SCIP). The 5 session P-SCIP was delivered during the HSCT hospitalization. Caregivers completed measures of distress, optimism, coping, and fear appraisals preintervention, 1, 6 months, and 1 year. Results P-SCIP reduced caregiver’s distress significantly more than BPC between the pretransplant assessment (Time 1) and 1-month follow-up assessment (Time 2). P-SCIP had a stronger effect than BPC among caregivers who began the hospitalization reporting higher depression and anxiety, and among caregivers whose children developed graft-versus-host disease (GvHD). Long-term treatment effects of P-SCIP were seen in traumatic distress among caregivers who reported higher anxiety pretransplant as well as among caregivers whose children had GvHD at HSCT discharge. Conclusions Screening caregivers for elevations in pretransplant anxiety and targeting interventions specifically to these caregivers, as well as targeting caregivers to children who develop GvHD, may prove beneficial.

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“…Depression and anxiety have been previously observed in mothers of children undergoing HSCT. 3,7,8,47,48 In one study, 15% of mothers (N=115) had moderate to severe depression based on the Beck Depression Inventory (BDI) and 18% of mothers had moderate to severe anxiety based on the Beck Anxiety Inventory.…”

Section: Discussionmentioning

confidence: 99%

Pilot Study of Parent Psychophysiologic Outcomes in Pediatric Hematopoietic Stem Cell Transplantation

et al. 2017

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Background Parents of children undergoing hematopoietic stem cell transplantation (HSCT) are at risk for psychological distress. This distress may result in aberrant immune, inflammatory or endocrine effects. These physiologic outcomes have not been reported previously. Main Objective To examine the feasibility of longitudinal testing of psychophysiological parameters of stress in parents of children undergoing HSCT. Methods This pilot study was conducted at a large children's hospital in the Midwest, and included parents of children who received autologous or allogeneic HSCT. Time points included: prior to start of HSCT conditioning, day +30, +60, and +100. Outcome variables included parent perceived stress, lymphocyte subsets, c-reactive protein (CRP), pro-inflammatory cytokines, salivary cortisol, and salivary amylase. Effect sizes were calculated for each outcome. Results Twelve parent-child dyads were enrolled (10 mothers, 2 fathers). Missing data was minimal. Parent perceived stress significantly increased from pre-HSCT through day +100, and parent CD3+ T lymphocyte counts decreased from pre-HSCT through day +100. No significant effects were observed for salivary studies, CRP, or pro-inflammatory cytokines. Effect sizes ranged from 1.23 (perceived stress) to 0.07 (CRP). Conclusion Results of this study suggest that it is feasible longitudinally measure parent psychophysiologic outcomes in the pediatric HSCT setting. Additionally, parent perceived stress increased linearly from start of conditioning through day +100, while parent T lymphocytes decreased concurrently. Implications for practice Routine psychological and physical health screening of parents of children undergoing HSCT are needed. Multidisciplinary psychosocial support services should be offered to parents at regular intervals during their child's HSCT.

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Adjustment in Parents of Children Undergoing Stem Cell Transplantation

Cited by 28 publications

References 32 publications

Characterizing the Pain Narratives of Parents of Youth With Chronic Pain

Characterizing the Pain Narratives of Parents of Youth With Chronic Pain

A randomized clinical trial of a parent-focused social-cognitive processing intervention for caregivers of children undergoing hematopoetic stem cell transplantation.

Pilot Study of Parent Psychophysiologic Outcomes in Pediatric Hematopoietic Stem Cell Transplantation

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