Adiposity and gingival crevicular fluid tumour necrosis factor‐<i>α</i> levels in children

Khosravi, Roozbeh; Tran, Simon D.; Lambert, Marie; O’Loughlin, Jennifer; Ka, Kanta; Feine, Jocelyne S.; Caron, C; Tremblay, Angelo; Nicolau, Belinda

doi:10.1111/j.1600-051x.2009.01374.x

Cited by 19 publications

(40 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This finding showed an association between childhood obesity and an increase in the plasma concentration of TNF-α and revealed a susceptibility to periodontal disease (29). However, this finding is in contrast to our study results.…”

Section: Discussioncontrasting

confidence: 99%

The Correlation Between Body Mass Index and Oral Health in 12-Year-Old Students in Tehran During 2011

Nakhostin¹,

Meighani²,

Abbasi³

et al. 2016

Avicenna J Dent Res

View full text Add to dashboard Cite

Background: The growing prevalence of being overweight and obesity in children has raised significant public health concerns. Obesity is considered a risk factor for several chronic health conditions and is associated with increased mortality. In addition, recent studies have shown an association between obesity and periodontal disease. Objectives: The present study sought to assess the correlation of body mass index (BMI) with periodontal disease. Materials and Methods: A total of 1,024 12-year-old elementary school students were selected by cluster sampling from five regions of Tehran. BMI was used as a measure of being overweight and obesity, and the oral hygiene index (OHI) was used to assess periodontal disease. A linear regression model was applied to estimate the association between BMI and OHI. The parents' level of education and family income were also evaluated.

show abstract

Section: Discussioncontrasting

confidence: 99%

The Correlation Between Body Mass Index and Oral Health in 12-Year-Old Students in Tehran During 2011

Nakhostin¹,

Meighani²,

Abbasi³

et al. 2016

Avicenna J Dent Res

View full text Add to dashboard Cite

show abstract

“…We are studying the Oral Health component within a cohort of 600 children in Quebec (the Quebec Adipose and Lifestyle Investigation in Youth; QUALITY cohort), which aims to investigate the natural history of obesity and its vascular and metabolic consequences [57]. Our results from the baseline visit of the QUALITY cohort so far indicate that obese boys, but not girls, have 37% higher levels of TNF- α , a risk factor for destructive periodontal disease, in their gingival crevicular fluid (GCF) compared to nonobese boys [58]. We also found that metabolic syndrome in boys was associated with 49 percent increase in the levels of TNF- α in gingiva crevicular fluid (Ka et al; unpublished data).…”

Section: Periodontal Diseases In Obesity and Metabolic Syndromementioning

confidence: 99%

Tumor Necrosis Factor-αand Interleukin-6: Potential Interorgan Inflammatory Mediators Contributing to Destructive Periodontal Disease in Obesity or Metabolic Syndrome

Khosravi

Huang

et al. 2013

Mediators of Inflammation

Self Cite

View full text Add to dashboard Cite

Obesity has become a worldwide health burden in the last two decades. Obesity has been associated with increased comorbidities, such as coronary artery disease, diabetes, and destructive periodontal disease. Obesity is also part of a group of risk factors occurring together in an individual, which is referred to as metabolic syndrome. Clinical studies have shown higher risk for destructive periodontal disease in obesity and metabolic syndrome. However, the role of obesity and metabolic syndrome in the onset and development of destructive periodontal disease has not yet been fully understood. In this review, we discuss a working model, which focuses on interorgan inflammation as a common etiological factor for destructive periodontal disease associated with obesity and metabolic syndrome. Specifically, we suggest that elevated levels of tumor necrosis factor-α (TNF-α) or interleukin 6 (IL-6)—both adipokines and known risk factors for destructive periodontal disease—in obesity and metabolic syndrome contribute to the onset and development of destructive periodontal disease. The connections between destructive periodontal disease and systemic conditions, such as obesity or metabolic syndrome, are complex and potentially multidirectional. This review largely focuses on TNF-α and IL-6, inflammatory mediators, as potential common risk factors and does not exclude other biological mechanisms.

show abstract

“…From a dentist’s perspective, obese children and adolescents appear to exhibit more carious lesions and cavities,15–20 although these findings are disputed 21. Other studies in adolescents have shown associations between obesity and periodontal risk indicators that – in the long-term – may lead to oral morbidity 22,23…”

Section: Introductionmentioning

confidence: 99%

Quantification of wear-time adherence of removable appliances in young orthodontic patients in relation to their BMI: a preliminary study

Schott¹,

Ludwig²

2014

PPA

View full text Add to dashboard Cite

PurposeThe relationship between unhealthy body mass index (BMI) and adherence to orthodontic treatment with removable appliances has not previously been evaluated.ObjectiveThe aim of this study was to quantify the association between BMI and wear time of removable orthodontic appliances and to evaluate BMI changes during orthodontic treatment.Patients and methodsFifty-three normal-weight and 39 overweight/obese children and adolescents (7–15 years old) undergoing orthodontic treatment with removable appliances were enrolled into the study. BMI categories were determined using standardized age-specific and sex-specific BMI criteria, using data measured at the beginning of therapy and once during orthodontic treatment. Wear times of removable appliances were measured at 15-minute intervals over a period of 5 months using implanted microelectronic sensors. Median wear-time values were used in the analysis with the Mann–Whitney U-test used to test statistical differences between groups.ResultsThe median wear time of removable orthodontic appliances was 9.3 hours for normal-weight patients and 9.2 hours for overweight/obese patients. No statistically significant (P>0.05) or clinically relevant differences in usage or adherence were detected between normal-weight and overweight/obese patients. BMI did not influence wear time or behavior of removable orthodontic appliances by young patients. The majority of patients showed qualitative decreases in BMI during therapy.ConclusionThe orthodontic treatment of young patients with removable devices does not require BMI-dependent changes in the treatment strategy. However, the use of removable appliances during meal times raises the possibility of reducing food intake, and in this way the orthodontist may have an active role to play in weight reduction.

show abstract

Adiposity and gingival crevicular fluid tumour necrosis factor‐α levels in children

Abstract: These findings provide support for the link between adiposity in children and GCF-TNF-alpha level, which appears to be mediated by insulin resistance.

Cited by 19 publications

References 33 publications

The Correlation Between Body Mass Index and Oral Health in 12-Year-Old Students in Tehran During 2011

The Correlation Between Body Mass Index and Oral Health in 12-Year-Old Students in Tehran During 2011

Tumor Necrosis Factor-αand Interleukin-6: Potential Interorgan Inflammatory Mediators Contributing to Destructive Periodontal Disease in Obesity or Metabolic Syndrome

Quantification of wear-time adherence of removable appliances in young orthodontic patients in relation to their BMI: a preliminary study

Contact Info

Product

Resources

About

Adiposity and gingival crevicular fluid tumour necrosis factor‐α levels in children

Abstract: These findings provide support for the link between adiposity in children and GCF-TNF-alpha level, which appears to be mediated by insulin resistance.

Cited by 19 publications

References 33 publications

The Correlation Between Body Mass Index and Oral Health in 12-Year-Old Students in Tehran During 2011

The Correlation Between Body Mass Index and Oral Health in 12-Year-Old Students in Tehran During 2011

Tumor Necrosis Factor-αand Interleukin-6: Potential Interorgan Inflammatory Mediators Contributing to Destructive Periodontal Disease in Obesity or Metabolic Syndrome

Quantification of wear-time adherence of&nbsp;removable appliances in young orthodontic patients in relation to their BMI: a preliminary study

Contact Info

Product

Resources

About

Quantification of wear-time adherence of removable appliances in young orthodontic patients in relation to their BMI: a preliminary study