Adipose tissue biomarkers of fatty acid intake

Abstract

Adipose tissue is a suitable biomarker of dietary fatty acid intake, particularly for n-3 and n-6 cis polyunsaturated fatty acids and trans fatty acids. Ideally, adipose tissue and dietary questionnaires should complement, rather than substitute for, each other in epidemiologic studies.

Intake of ruminant trans fatty acids and changes in body weight and waist circumference

“…34,35 Published correlation coefficients between TFA intake (as percentage of total fat) estimated from FFQ and the proportion of TFA in adipose tissue have varied between 0.29 and 0.67. [36][37][38][39][40] Biomarkers may provide a more accurate measure of TFA intake than obtained with FFQ since biomarkers of dietary intake are not affected by the participants' memory or differential reporting. However, it is not possible to quantify TFA intakes from proportions of TFA in adipose tissue.…”

Trans-fatty acids in cooking oils in Bogota, Colombia: changes in the food supply from 2008 to 2013

“…Fatty acids were esterified with a methylating reagent containing methanol (2 ml) and acetyl chloride (0·1 ml) as previously described (14,16) . After esterification, the methanol and acetyl chloride were evaporated off and the fatty acid methyl esters were redissolved in isooctane.…”

Adipose tissue arachidonic acid and the metabolic syndrome in Costa Rican adults

“…21 The control subjects were chosen via the Costa Rican National Census and Statistics Bureau at random throughout the greater San Jose area, which included 18 counties and comprised a full range of socioeconomic levels (although middle-income households predominate in Costa Rica) and urban (57%), suburban (28%) and rural (15%) lifestyles. The participation rate was 90%.…”

“…21,23 Dietary information from the FFQ was used to test whether the adipose tissue associations were independent from dietary intake.…”