Adiponectin levels do not change with moderate dietary induced weight loss and exercise in obese postmenopausal women

Ryan, Alice S.; Nicklas, Barbara J.; Berman, Dora M.; Elahi, Dariush

doi:10.1038/sj.ijo.0802387

Cited by 152 publications

(122 citation statements)

References 22 publications

Supporting

Mentioning

107

Contrasting

Unclassified

Order By: Relevance

“…Training studies have shown that exercise might not be a significant factor towards adiponectin modifications (Marcell et al 2005;Ryan et al 2003). It seems that modifications in body weight or body composition might be responsible for alterations in adiponectin levels (Esposito et al 2003;Hulver et al 2002;Monzillo et al 2003).…”

Section: Discussionmentioning

confidence: 99%

The effects of acute exercise on serum adiponectin and resistin levels and their relation to insulin sensitivity in overweight males

et al. 2006

View full text Add to dashboard Cite

The purpose of this study was to investigate the effects of a submaximal aerobic exercise bout on adiponectin and resistin levels as well as insulin sensitivity, until 48 h post-exercise in healthy overweight males. Nine subjects performed an exercise bout at an intensity corresponding to approximately 65% of their maximal oxygen consumption for 45 min. Adiponectin, resistin, cortisol, insulin, glucose and insulin sensitivity were measured prior to exercise, immediately after exercise as well as 24 and 48 h after exercise. Data were analyzed using repeated measures ANOVA while Pearson's correlations were performed to identify possible relationship among the assessed variables. There were no significant differences for adiponectin (lg ml À1 ) [pre Insulin sensitivity increased and insulin concentration decreased significantly only immediately after exercise. Furthermore, no significant correlations were observed among the variables assessed except for the expected between insulin level and insulin sensitivity. These results indicate that a submaximal aerobic workout does not result in significant changes in adiponectin and resistin up to 48 h post-exercise. Furthermore, it appears that adiponectin or resistin is not associated with insulin sensitivity.

show abstract

Section: Discussionmentioning

confidence: 99%

The effects of acute exercise on serum adiponectin and resistin levels and their relation to insulin sensitivity in overweight males

et al. 2006

View full text Add to dashboard Cite

show abstract

“…It has been shown that basal adiponectin concentration was not altered after longterm exercise [10][11][12][13][14]. In contrast, Kriketos et al [15] recently reported that fasting adiponectin levels increased by 260% above baseline values after 2-3 bouts of low to moderate intensity exercise.…”

mentioning

confidence: 97%

“…Several studies exploring the effects of exercise on circulating adiponectin levels have resulted in inconsistent findings [10][11][12][13][14][15]. It has been shown that basal adiponectin concentration was not altered after longterm exercise [10][11][12][13][14].…”

mentioning

confidence: 99%

Effect of Exercise on Circulating Adipokine Levels in Obese Young Women

2006

View full text Add to dashboard Cite

Abstract. We studied the effect of exercise on circulating adipokine, high sensitivity C-reactive protein (hs-CRP), and metabolic parameters in obese young women. Ninety-six healthy Japanese young female students aged 18-23 years were studied. The longitudinal intervention study of a 7-month exercise training program (30-60 min/day, 60-70% HRreserve, 200-400 kcal, 4-5 days/week) was performed in eight obese female students (BMI ³25 kg/m 2 ). Eight control female students (mean BMI = 22 kg/m 2 ) were included in the follow-up study. Body weight, body mass index (BMI), percentage of body fat (%Fat), body fat mass, lean body mass, health-promoting lifestyle profile-scale (L-scale), Vo 2 max (maximal oxygen uptake), hs-CRP, lipids, insulin homeostasis model assessment (HOMA-R), fasting levels for circulating adiponectin, leptin, and TNF-a, were measured before and after the exercise program. In obese subjects, body weight, BMI, %Fat, body fat mass, lean body mass, hs-CRP, leptin, and TNF-a were significantly higher, and L-scale and adiponectin were lower than those in control subjects. In obese subjects, exercise decreased body weight, BMI, %Fat, body fat mass, lean body mass, hs-CRP, leptin, and TNF-a, and increased L-scale, Vo 2 max, HDL-cho, and adiponectin. It was concluded that changes in circulating adipokine levels are involved in the improvement of the metabolic state by exercise and may be useful markers for evaluation and prescription of exercise.

show abstract

“…29,34,[45][46][47][48][49][50][51][52][53][54][55] Female data were compiled from 15 studies (26 groups of individuals), with study sample size ranging from 8 to 662 individuals and a mean sample size of 94. 29,45,46,48,50,[53][54][55][56][57][58][59][60][61][62] Lack of BMI-adiponectin association S-M Kuo and MM Halpern Among these studies, eight studies included subjects of both genders and the measurements from men and women were reported separately. The sample size as well as the age and BMI profiles of these studies are summarized in Table 1.…”

Section: Data Collectionmentioning

confidence: 99%

“…The regression analysis of female adiponectin to leptin was based on data from 13 groups 45,50,53,54,56,58,61,62 and Pearson's correlation was 0.37 (P40.05, not significant). The analysis confirmed the expected lack of correlation between adiponectin and leptin in healthy individuals.…”

Section: Lack Of Bmi-adiponectin Association S-m Kuo and MM Halpernmentioning

confidence: 99%

Lack of association between body mass index and plasma adiponectin levels in healthy adults

Kuo

2011

Int J Obes

View full text Add to dashboard Cite

Objectives: To test the hypothesis that obesity (increase in fat mass) independently affects the level of adipokines: adiponectin, tumor necrosis factor-a (TNFa) and interleukin (IL)-6. Methods: Publications in the past decade reporting adult plasma adiponectin, leptin, TNFa and/or IL-6 levels were compiled. Mean gender-specific values were extracted from studies that included medical screening to confirm physical health (43 groups, total 4852 subjects). Correlation analysis was conducted between adipokine levels and body mass index (BMI), a widely used estimate of adiposity. Results: For healthy lean to obese adults of both genders, no significant correlation between plasma adiponectin and BMI was detected. There was also no gender difference in plasma adiponectin level. In contrast, leptin levels showed a positive correlation with BMI in both genders, and women had significantly higher levels of plasma leptin consistent with a higher percentage of body fat. The proinflammatory cytokine TNFa failed to show correlation with BMI. Although IL-6 showed a positive correlation with BMI in women, the obesity-related increase was very limited. Conclusions: Data analysis based on studies performed on healthy adults did not support the hypothesis that obesity independently affects the plasma level of adiponectin and TNFa. Reported obesity-related changes in plasma adipokine levels may be a consequence of obesity-related metabolic disorders. Future studies are especially needed to understand the homeostasis of adiponectin.

show abstract

Adiponectin levels do not change with moderate dietary induced weight loss and exercise in obese postmenopausal women

Cited by 152 publications

References 22 publications

The effects of acute exercise on serum adiponectin and resistin levels and their relation to insulin sensitivity in overweight males

The effects of acute exercise on serum adiponectin and resistin levels and their relation to insulin sensitivity in overweight males

Effect of Exercise on Circulating Adipokine Levels in Obese Young Women

Lack of association between body mass index and plasma adiponectin levels in healthy adults

Contact Info

Product

Resources

About