Adiponectin and highly sensitive C-reactive protein levels in obese children aged 9 to 15 years

Abstract

Background problem associated with health problems such as metabolic syndrome, diabetes mellitus and cardiovascular disease. A low-grade chronic inflammatory state, reflected by decreased with obesity. Objective in obese and normal weight children. Methods We conducted a cross-sectional, case-controlled study We performed physical examinations, measured blood pressure, weight and height, and calculated BMI for all subjects. After an overnight fast, all subjects were tested for fasting blood glucose, Results The mean adiponectin level in the obese group was 3.6 Conclusions obese group is consistent with a low-grade chronic inflammatory further evaluation. Early intervention is needed to reduce body weight in obese children. [Paediatr Indones. 2011;51:7-11].

Hubungan Kadar 25-Hydroksivitamin D dan High Molecular Weight Adiponectin pada Remaja Obes

“…25 Pada laporan penelitian remaja obes yang dilakukan di Manado mendapatkan kadar total adiponektin 3,59 (SB 1,43) µg/mL, sedangkan sebelumnya di Semarang adalah 4,08 (SB 0,81) µg/mL. 14,15 Belum ada data kadar HMW adiponektin pada remaja obesitas di Indonesia. Rerata kadar HMW adiponektin dalam penelitian kami adalah 1014,58 (SB 458,94) ng/mL.…”

“…Penelitian mengenai 25(OH)D dan HMW adiponektin pada remaja obes khususnya di Indonesia masih sedikit. [13][14][15] Belum ada laporan mengenai hubungan 25(OH)D dan HMW adiponektin. Karena itu, tujuan penelitian ini untuk menilai hubungan antara kadar 25(OH)D dan HMW adiponektin.…”

The Correlation Between Adiponectin Levels With C-Reactive Protein in Adult Obese Non-Diabetic Among Staffs of DR. M. Djamil Hospital Padang

“…5 Decreasing level of adiponectin as an anti-inflammation marker and increasing of C-reactive protein (CRP) show a lower grade of chronic inflammation. 3,6,7 Adiponectin is a collagen-like plasma protein secreted particularly by adipocytes. 8,9 Clinical studies revealed that hypoadiponectinemia is one of the independent risk factors for cardiovascular disease, 10 insulin resistance, and type 2 diabetes.…”

“…17 Chronic low-grade inflammation is indicated by a decrease in adiponectin levels and an increase in CRP levels. 6,7 Significantly negative correlations between adiponectin and CRP were reported in populations with obesity, type 2 diabetes, and coronary artery disease. 1,18 Adiponectin levels of <3,0 µg/mL and CRP 3,0 ng/mL are stated as abnormal results.…”

“…They found that there was no significant correlation between adiponectin and CRP levels (r=0,048; p=0,362). 6 Amudi et al examined CRP and adiponectin levels in 30 young adult males with central obesity at Prof. Dr. R. D. Kandou Hospital, Manado. Amudi used different cut off high CRP levels >0.1 mg/dL (10 µg/mL) and low adiponectin levels <5000 ng/mL.…”