Abstract:The adhesion of tear proteins to contact lenses contributes to lens deterioration and ocular pathology. Tears contain a number of proteins, predominantly lysozyme. Here we examine the adhesion of human lysozyme to FDA group III (low water, ionic) contact lenses comprised of a copolymer of silicon vinyl carbamate, N‐vinyl‐pyrrolidone, with a siloxane crosslinker and a vinyl alanine wetting monomer. These lenses are 36% water by weight. Lenses were incubated in a solution of lysozyme for 1, 2, 3, and 4 days, and… Show more
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