Adherence to medication and physical activity among people living with HIV/AIDS

Morowatisharifabad, Mohammadali; Movahed, Ehsan; Nikooie, Rohollah; Farokhzadian, Jamileh; Bidaki, Reza; Askarishahi, Mohsen; Hosseinzadeh, Mahdieh

doi:10.4103/ijnmr.ijnmr_205_18

Cited by 8 publications

(7 citation statements)

References 10 publications

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“…Age of antiretroviral therapy patients was a major determinant of lost to follow up, antiretroviral therapy patients were three times more likely to be missed from therapy in the age group of 15–24 years than patients over 45 years of age, this may be because those 15–24 years of age do not have a permanent job as much as most of the time they have a temporary address, this finding is consistent with the outcome of the study in Iran, 23 Ethiopia, 22 India, 18 Malawi. 17 …”

Section: Discussionsupporting

confidence: 84%

Influence of Lost to Follow Up from Antiretroviral Therapy Among Retroviral Infected Patients at Tuberculosis Centers in Public Hospitals of Benishangul-Gumuz, Ethiopia

Degavi¹

2021

HIV

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Background: Broadening access to healthcare (ART) antiretroviral therapy has led to a 19% reduction in the death rate of people infected with the human immunodeficiency virus. This study would also describe the status and deciding factors of ART in (TB) tuberculosis centers in public hospitals of Benishangul-Gumuz, Ethiopia, for (LTFU) lost follow-up among (RVI) retroviral infected patients. Methods: Hospital-based, unrivalled analysis of the case management (3:1) design was conducted. A total of 752 study participants (563 controls and 189 cases) Picked by systematic random sampling methodology, and where reviewed their charts from TB Centers. Data were entered and cleaned using Epi data version 3.1.1 and then exported to SPSS version 22 for analysis. To analyze the statistical relationship between the outcome variable and independent variables, binary logistic regression was used. Relevance was declared at a p-value <0.05. Results: A total of 1122 (25.3%) were LTFU. Among index cases with male cases, there were higher odds of lost to follow up (AOR= 1.68, 95% CI; 1.085, 2.609), 15-24 old age group have no formal education, civil servant were also having high comparatively. In index cases with identified parents, the risk of LTFU up had lower HIV status (AOR=0.5; 95% CI; 0.24, 0.997). Rest all variables showed low odds to LTFU. Conclusion: A large number of patients enrolled in ARTwere missing from follow-up at TB centers, but unfortunately did not make the next appointment reported. The absence of prophylaxis was accepted as an independent determinant of LTFUfor ART.

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Section: Discussionsupporting

confidence: 84%

Influence of Lost to Follow Up from Antiretroviral Therapy Among Retroviral Infected Patients at Tuberculosis Centers in Public Hospitals of Benishangul-Gumuz, Ethiopia

Degavi¹

2021

HIV

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“…This finding suggested poorer antiretroviral adherence in PLWH, and supports previous reports that estimating adherence based on medication dose alone may overestimate the true adherence level. [49][50][51] Consequentially, a more appropriate measurement of adherence may need to consider all antiretroviral requirements including medication dose, schedule, and instruction. Older PLWH were observed to have better antiretroviral adherence compared to younger adults.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the Sociodemographic, Behavioral and Clinical Influences on Complete Antiretroviral Therapy Adherence Among HIV-Infected Adults Receiving Medical Care in Houston, Texas

Sok

Mgbere

Pompeii

et al. 2021

HIV

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Introduction: Few studies have estimated complete antiretroviral therapy (ART) adherence following HIV infection since the advent of the new ART guidelines in 2012. This study determined the prevalence and influence of sociodemographic, behavioral, and clinical factors on complete ART adherence among people living with HIV (PLWH) receiving medical care in Houston/Harris County, Texas. Methods: Data from the Houston Medical Monitoring Project survey collected from 2009 to 2014 among 1073 participants were used in this study. The primary outcome evaluated was combined adherence, defined as complete, partial, and incomplete combined adherence based on three ART adherence types-dose, schedule, and instruction adherence. The duration living since initial HIV diagnosis was classified as <5, 5-10 and >10 years. Rao-Scott Chisquare test and multivariable proportional-odds cumulative logit regression models were employed to identify the sociodemographic, behavioral, and clinical characteristics of complete combined adherence among the three groups of PLWH living with HIV infection. Results: More than one-half (54.4%) of PLWH had complete, 37.4% had partial, and 8.3% had incomplete combined adherence. Among these PLWH, 52.2% had been infected with HIV for >10 years, and 26.5% and 21.4% were infected for <5 years and 5-10 years, respectively. PLWH who were diagnosed <5 and 5-10 years were two times (aOR=1.71, 95% CI=1.13-2.57; aOR=1.69, 95% CI=1.10-2.59; respectively) more likely to experience complete combined adherence than those with >10 years of infection. Multiple sociodemographic, behavioral, and clinical characteristics were significantly associated with complete adherence and varied by the duration of HIV infection. Conclusion:Measures of adherence should include all adherence types (dose, schedule, instruction), as utilizing a single adherence type will overestimate adherence level in PLWH receiving medical care. Intervention efforts to maintain adherence should target recently infected PLWH, while those aimed at improving adherence should focus on longer infected PLWH.

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“…Although there has been a dramatic change in the coverage of ART services across the globe to include low- and middle-income countries, there are still challenges in helping patients to adhere to their initiated antiretroviral drugs. 6 Findings from North America showed that only 55% (n=17,573) of PLWHIV have an adherence level greater than 80%. In Africa, meta-analysis data showed that 77% of patients adhered to their medication, by considering an 80% cut-off value.…”

Section: Introductionmentioning

confidence: 99%

Adherence and Its Associated Factors Among Adult HIV-Infected Patients on Antiretroviral Therapy in South Western Ethiopia, 2020

Angelo¹,

Alemayehu²

2021

PPA

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Background Good adherence to antiretroviral therapy (ART) suppresses the viral load, reconstitutes the immune system, and decreases opportunistic infections among HIV-positive patients. However, adherence to ART is still challenging in developing countries such as Ethiopia. The study, therefore, aimed to assess adherence and its associated factors among HIV-positive patients on ART in southern Ethiopia in 2020. Materials and Methods A cross-sectional study was conducted among 329 randomly selected participants. A structured questionnaire was used to collect the data through a face-to-face interview from January 23 to February 23, 2020. Data were entered into Epidata 3.1 and exported to SPSS version 21 for analysis. Bivariate and multivariate logistic regressions were used for analysis. A p -value of less than 0.05 was considered significant in a multivariate logistic regression analysis. Results In total, 274 patients (83.3%) had good adherence to ART, while 16.7% did not adhere. Age between 39 and 49 years old (AOR=0.068, 95% CI 0.008, 0.578), urban residency (AOR=5.186, 95% CI 1.732, 15.529), an educational status of being unable to read and write (AOR=0.097, 95% CI 0.012, 0.771), an educational status of reading and writing with no formal education (AOR=0.056, 95% CI 0.006, 0.532), comorbidity (AOR=0.042, 95% CI 0.013, 0.139), disclosure (AOR=3.583, 95% CI 1.008, 12.739), WHO clinical stage II (AOR=0.098, 95% CI 0.021, 0.453), and CD4 count ≥500 cells/mm 3 (AOR=5.634, 95% CI 1.203, 26.383) were significantly associated with adherence to ART among patients. Conclusion The adherence of patients to ART is relatively low compared to other studies conducted in different regions. Age 39–49 years, educational status, comorbidity, and WHO clinical staging were negatively associated with ART adherence. Residency, disclosure, and current CD4 category greater than or equal to 500 cells/mm 3 were positively associated with adherence. Good counseling to patients from rural areas, with low educational status, and with low CD4 counts, and on the importance of disclosure, is recommended and should be given by professionals.

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Adherence to medication and physical activity among people living with HIV/AIDS

Cited by 8 publications

References 10 publications

Influence of Lost to Follow Up from Antiretroviral Therapy Among Retroviral Infected Patients at Tuberculosis Centers in Public Hospitals of Benishangul-Gumuz, Ethiopia

Influence of Lost to Follow Up from Antiretroviral Therapy Among Retroviral Infected Patients at Tuberculosis Centers in Public Hospitals of Benishangul-Gumuz, Ethiopia

Evaluation of the Sociodemographic, Behavioral and Clinical Influences on Complete Antiretroviral Therapy Adherence Among HIV-Infected Adults Receiving Medical Care in Houston, Texas

Adherence and Its Associated Factors Among Adult HIV-Infected Patients on Antiretroviral Therapy in South Western Ethiopia, 2020

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