Adherence to antiepileptic drugs and beliefs about medication among predominantly ethnic minority patients with epilepsy

Abstract

The current study examined beliefs about medication and their association with adherence to antiepileptic drugs (AEDs) among predominantly ethnic minority, low-income patients with epilepsy (PWE). Seventy-two PWE completed standardized questionnaires. The Beliefs about Medicines Questionnaire was used to assess perceptions about AEDs and medications in general. Adherence was measured with the Morisky 4-item scale and via participant self-rating. On the Morisky scale, 63% of patients endorsed at least one item for nonadherence. There was a significant relationship between seizure frequency and adherence (Morisky: r= 0.33, p= 0.006; Self-rating: r =−0.35; p= 0.003). Patients with lower self-rated adherence expressed greater concerns about AEDs (r= −0.25, p= .036) and beliefs that medications, in general, may be intrinsically harmful (r= −0.26; p= 0.032) and minimally beneficial (r= 0.36; p< 0.002), as compared to more adherent patients. These findings inform future educational interventions in this population of PWE.

Não adesão ao tratamento medicamentoso contínuo: prevalência e determinantes em adultos de 40 anos e mais

“…Entre as consequências da não adesão, é possível pontuar a diminuição do controle efetivo das doenças 3,4,17,18,23 , o aumento no risco de hospitalizações 24 e o aumento da mortalidade 25 . A avaliação em extensão do impacto da não adesão representa um desafio, pois não há consenso sobre a forma de mensuração e há pouca disponibilidade de informações que permitam analisar fator associado a eventuais complicações, hospitalizações, mortes e custos diretos e/ ou indiretos 5,6,21,26 .…”

“…Tal escala possui utilização corrente no meio científico, simplicidade de aplicação e correlação com medidas do desfecho clínico 13,17,18 16 .…”

Prevalence and Associated Factors of Antiepileptic Drugnonadherence Among Epileptic Patients Attending at Out Patient Departement of Dilla University Referral Hospital, Dilla,gedeo,snnpr, Southern Ethiopia

“…The probable explanation for this difference may be due to: the study design used, the medication prescribed, methods used to measure the non adherence and as well as difference in socio-demographic characteristics of the study participant or due to study area. But the nonadherence was smaller than those studies in Brazil, Nigeria and Palestine which were 66.2%, 67.4% and 64% respectively (28,31,40) The difference from Brazil study might be due to duration of treatment and prescribed AEDs which were 71.1% of the respondents were on two to five AEDs and the mean duration of treatment was 21.5year. In this study the participants who were on two medications was 18.1% and the mean of treatment duration was 1.9 years and the difference in Nigeria might be due to socio-demographic characteristics and poly-therapy which was 85%of the participant took three and above AEDs.…”

Reduserer språkbarrierer på sykehus

“…Det kan føre til ukontrollert anfallssituasjon, flere bivirkninger, økt stigmatisering og redusert livskvalitet (19,20).…”