Goal: Analyze and identify the adherence of type 2 diabetics to treatment reported in the literature in addition to describing the role of nurses in the treatment of type 2 diabetes mellitus. Methods: This is an integrative review. The data search was carried out in April 2020, in the databases LILACS - Latin American and Caribbean Literature in Health Sciences, MEDILINE - Online Literature Search and Analysis System and BDENF - Nursing Databases. The following descriptors were used according to the Health Sciences Descriptors (DeCS). To cross the terms, the Boolean logical operator “and” was used in order to obtain the largest number of articles that answer the guiding question. Result and discussion: Se establecieron variables relevantes para la observación en forma de gráficos y tablas. In order to better assimilate the data, the following thematic categories emerged: Type 2 diabetic adherence to treatment; nursing consultation as an intervention in the treatment. Final Considerations: Socioeconomic factors and personal experiences can interfere in the conception of health in which knowledge and self-care practices are fundamental for therapeutic adherence, as well as the reception between the health professional and the patient, increasing the effectiveness of the assistance and improving the acceptance of the patient treatment.