Adenylic nucleotides and energy charge during the embryonic development of Bufo arenarum

Living organisms influence on environmental conditions: pH modulation by amphibian embryos versus aluminum toxicity

“…Could the remarkable embryo's-mediated pH modulation in the maintaining media reflect environmental features during the evolutionary process? Considering ontogenic features such as stage-dependent biochemical or physiological features (Sivori et al, 1986;Castane et al, 1987) and stage-dependent susceptibility to noxious agents (Pérez-Coll and Herkovits, 1990;Herkovits et al, 1996) as biomarkers of the coevolution between living forms ancestors and environmental signatures during Earth's history, a new Onto-Evo synthesis was provided (Herkovits, 2006), confirmed by subsequent studies focusing on stage dependent susceptibility both to physical (Castañaga et al, 2009) and chemical agents (Sztrum et al, 2011). The theory includes a new datation method, e.g.…”