Adenoviral Pancreatitis in Guinea Fowl (Numida meleagris)

Abstract

Necrotizing pancreatitis was observed in 2-week-old Guinea fowl submitted for necropsy and histopathology. Intranuclear inclusion bodies seen histologically in acinar epithelium were examined by electron microscopy and found to contain viruses resembling adenovirus. Adenovirus was isolated in embryonated eggs from the pancreata of affected birds. The adenovirus isolated was not neutralized by chicken antisera developed against 10 known serotypes of group 1 avian adenoviruses.

Analysis of adenovirus strains isolated from poultry in Poland

“…The role of adenoviruses as the opportunistic factors is indicated (7). They can cause asymptomatic infections, but also they are an aetiological agent of diseases such as inclusion body hepatitis -IBH (6), hydropericardium hepatitis syndrome -HHS (7), gizzard erosion and ulceration (GEU) (20), and pancreatitis (24). Adenoviruses can be one of the reasons of immunodeficiency.…”

Occurrence of Adenovirus Field Strains in Birds Infected with Marek’S Disease Virus

“…In one case they can cause asymptomatic infections, in another they are an aetiological agent of diseases such as inclusion body hepatitis -IBH (6,19) or hydropericardium hepatitis syndrome -HHS (14). The viruses have been also isolated from birds with respiratory tract diseases (22), gizzard erosion and ulceration (GEU) (5,21,23), and pancreatitis (30). Adenoviruses can be the reason of immunodeficiency in young chicks, that can further lead to suppression of the immunity after the vaccination against Marek's disease.…”

Gross and Histologic Lesions of Adenovirus Group I in Guinea Fowl

“…Guinea fowl are susceptible to avian adenovirus. 1,5,7,10 Pulmonary edema, splenomegaly, and ascites have been observed in adult guinea fowl and resembled marble spleen disease of pheasants.…”

“…Necrotizing pancreatitis in 2-3-week-old guinea fowl has been associated with avian adenovirus infections. 7,10 Gross and microscopic lesions were confined to the pancreas. The adenovirus isolated from the pancreas was not neutralized by antisera against 10 known serotypes of group I avian adenovirus.…”

“…The adenovirus isolated from the pancreas was not neutralized by antisera against 10 known serotypes of group I avian adenovirus. 10 A case involving excessive mortality in a flock of guinea fowl was submitted to the Turlock Branch of the California Veterinary Diagnostic Laboratory System. These birds had classical adenovirus infection with necrosis and intranuclear inclusion bodies in the pancreas.…”