Adenolipomas of the head and neck: analysis of 6 cases

Daboin, Keyla Pineda; Ochoa-Perez, Valentina; Luna, Mario A.

doi:10.1016/j.anndiagpath.2005.07.012

Cited by 31 publications

(25 citation statements)

References 22 publications

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“…They have been described in many anatomic sites, including the skin, breast, parathyroid, thyroid, and salivary gland [24][25][26][27][28][29][30][31]. Mixed lipomatous and epithelial tumors where the latter component is comprised of oncocytes have been termed oncocytic lipoadenoma, which appear to be unique to salivary glands.…”

Section: Discussionmentioning

confidence: 99%

Oncocytic Lipoadenoma of the Salivary Gland: A Clinicopathologic Analysis of 7 Cases and Review of the Literature

Lau

Thompson

2014

Head and Neck Pathol

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Oncocytic lipoadenoma is an exceedingly uncommon neoplasm of the salivary gland composed of oncocytic epithelium and adipose tissue. Retrospective. Seven cases of oncocytic lipoadenoma were analyzed in order to further characterize the clinical and pathologic features of this rare tumor. The patients included six males and one female who ranged from 40 to 83 years of age (mean 62 years) at presentation. All tumors arose in the parotid gland. Grossly, the tumors were solitary, well circumscribed and had light brown to yellow cut surfaces. Histologically, the tumors were composed of an admixed population of oncocytes and adipocytes in varying proportions, with the lipomatous component ranging from 5 to 70 %. Other common features included the presence of serous acini, ductal elements, sebaceous glands, and a patchy chronic inflammation. Clinical follow up information, available in all cases, with a duration of 3-148 months (mean 57 months), showed no evidence of tumor recurrence. Due to its rarity, oncocytic lipoadenoma can pose problems in diagnosis, although the distinctive morphologic features of this neoplasm allow for separation from more commonly recognized oncocytic neoplasms of the salivary glands.

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Section: Discussionmentioning

confidence: 99%

Oncocytic Lipoadenoma of the Salivary Gland: A Clinicopathologic Analysis of 7 Cases and Review of the Literature

Lau

Thompson

2014

Head and Neck Pathol

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“…These lesions have been published in the recent literature as single case reports under different names (oncocytic sialolipoma, oncocytic lipoadenoma and adenolipoma) [21,27,28]. To date, around 15 cases of oncocytic lipoadenomas have been reported; a majority of them featured foci of sebaceous differentiation [19][20][21].…”

Section: Oncocytic Lipoadenomamentioning

confidence: 99%

Fat-Containing Salivary Gland Tumors: A Review

Agaimy

2013

Head and Neck Pathol

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Fat-containing tumors of the salivary glands are uncommon. Their wide histological spectrum varies from pure lipomatous neoplasms similar to their cutaneous and soft tissue counterparts to mixed lipoepithelial lesions specific to the salivary glands. With few exceptions, these uncommon lesions affect mainly the elderly, with a mean age at presentation of C50 years and show a predilection for males. A few cases occur in childhood; some of them represent congenital lesions. In decreasing order of frequency, ordinary (soft-tissue type) lipoma, oncocytic lipoadenoma, non-oncocytic sialolipoma, and pleomorphic adenoma/myoepithelioma with extensive lipometaplasia are the main variants of fat containing tumors encountered in the salivary glands. While pleomorphic adenoma/myoepithelioma with lipometaplasia behave in the same way as their non-fat-containing counterparts, other lipomatous salivary gland tumors listed above are cured with simple excision and do not carry a risk of recurrence. Other lipoma variants (spindle cell lipoma, osteolipoma, fibrolipoma, angiolipoma, pleomorphic lipoma, lipoblastoma and hibernoma) are exceptionally rare in the salivary gland. Atypical lipomatous tumors/liposarcoma have been only rarely reported in the salivary gland and they behave in a similar fashion to their soft-tissue counterparts. Diffuse lipomatosis and lobular fatty atrophy are the two tumor-like lesions that might closely mimic sialolipoma, particularly in limited biopsy material without knowledge of the gross findings. This review summarizes the clinicopathological features of the main types of salivary fat-containing lesions and discusses their differential diagnoses.

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“…Residual lesion was found in the inferior part of right thyroid gland the reported cases had been investigated from pathological or surgical perspectives. Differential diagnosis in pathology should include parathyroid adenoma, thyroid adenoma, thyroid lipoadenoma, parathyroid carcinoma, and thyroid carcinoma, with the last two being the lesions of the greatest concern [1][2][3][4][5]. This fat-containing tumor may grossly resemble lipoma more than parathyroid adenoma, so distinguishing these lesions can be challenging during intraoperative consultation, and more importantly en bloc parathyroidectomy could be compromised [5].…”

Section: Discussionmentioning

confidence: 99%

“…Parathyroid lipoadenoma is a rare entity that is composed of parathyroid chief cells and fatty stroma [1][2][3][4][5]. The name of parathyroid lipoadenoma was first used by Abul-Haj et al [6] who reported such a case.…”

Section: Introductionmentioning

confidence: 99%

Tc-99m sestamibi parathyroid imaging in a rare case of parathyroid lipoadenoma

et al. 2009

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Parathyroid lipoadenoma is an unusual cause of primary hyperparathyroidism. Only a few earlier reports have documented parathyroid imaging in diagnostic studies of parathyroid lipoadenoma. Our case was a 27-year-old man, who was originally diagnosed with primary hyperparathyroidism. He underwent a Tc-99m sestamibi dual-phase parathyroid imaging study, which revealed a right-inferior parathyroid hyperfunctional lesion. The first operation removed a lesion of 1.5 cm in diameter in the area, and parathyroid lipoadenoma was diagnosed by pathology. However, hypercalcemia persisted. One week later, a Tc-99m sestamibi whole-body scan and another dual-phase imagining were performed, which demonstrated a residual lesion in the inferior part of the right thyroid region, while no ectopic lesion was found. A second surgery was performed and pathological diagnosis was confirmed as parathyroid lipoadenoma again. Our case demonstrated that although hyperfunctional parathyroid lipoadenoma is rare, Tc-99m sestamibi parathyroid imaging is reliable in locating the lesion for surgical purposes. And Tc-99m sestamibi imaging is useful in reoperative and persistent hyperparathyroidism situations as well.

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Adenolipomas of the head and neck: analysis of 6 cases

Cited by 31 publications

References 22 publications

Oncocytic Lipoadenoma of the Salivary Gland: A Clinicopathologic Analysis of 7 Cases and Review of the Literature

Oncocytic Lipoadenoma of the Salivary Gland: A Clinicopathologic Analysis of 7 Cases and Review of the Literature

Fat-Containing Salivary Gland Tumors: A Review

Tc-99m sestamibi parathyroid imaging in a rare case of parathyroid lipoadenoma

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