Adenoid cystic carcinoma of the Bartholin's gland: the University of Michigan experience

Lellé, Ralph J.; Davis, Kenneth P.; Roberts, James A.

doi:10.1046/j.1525-1438.1994.04030145.x

Cited by 37 publications

(29 citation statements)

References 7 publications

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“…The tumor has a protracted [2] but malignant clinical course, with a propensity for local recurrence. Its physical history is relatively slow and local recurrence and distant metastases by intravascular spread may occur over a long period of time [10]. Metastasis to the inguinal femoral lymph nodes is uncommon.…”

Section: Discussionmentioning

confidence: 99%

“…It is probably prudent to use 10-to 15-year survival rates rather than 5-year survival curves when evaluating therapy for this tumor [2,7,8]. According to Copeland et al [7] and Lelle et al [10], the 10-year progression-free interval was 38 and 33%, respectively, compared to a survival rate of 59 and 100%, respectively, confirming a protracted although malignant clinical course of the disease. Patients may live for extended intervals even with metastatic disease.…”

Section: Discussionmentioning

confidence: 99%

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Adenoid Cystic Carcinoma of Bartholin’s Gland

Nasu¹,

Kawano²,

Takai³

et al. 2005

Gynecol Obstet Invest

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Adenoid cystic carcinoma of Bartholin’s gland is characterized by slow growth, local invasion, and sometimes distant metastasis. There is no consensus regarding the optimal treatment. We report herein a rare case of stage II adenoid cystic carcinoma of Bartholin’s gland that was successfully treated by wide local excision of the tumor and ipsilateral inguinal and pelvic lymphadenectomy. A 54-year-old Japanese woman was admitted complaining of painless, gradually increasing vulvar mass existing from ten years before. Local examination revealed a 3 × 2-cm hard mass in the left labium major. Pathological examination of subsequent excisional biopsy revealed adenoid cystic carcinoma originating in the Bartholin’s gland. A wide local resection of the tumor with inguinal and pelvic lymphadenectomy was performed. The tumor was completely excised with free margins. There was no metastasis in the resected lymph nodes. The patient was diagnosed as having stage II vulvar cancer according to the International Federation of Gynecologists and Obstetricians classification (1988). The patient is now healthy without evidence of recurrence at 5 years after surgery. Adenoid cystic carcinoma of Bartholin’s cyst at early stage can be treated by wide local excision as a primary surgery.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Adenoid Cystic Carcinoma of Bartholin’s Gland

Nasu¹,

Kawano²,

Takai³

et al. 2005

Gynecol Obstet Invest

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“…En la intervención con intención curativa realizar lifadenectomía regional y radioterapia posterior en caso de encontrar criterios oncológicos de agresividad 1,[3][4][5][6][7][8][9][10][11][12] .…”

Section: Presentación Del Casounclassified

Metastasis pulmonares tardías de carcinoma adenoideo quístico de la glandula de bartolino.

Quiroz

Moya

Rojas

et al. 2017

Rev. chil. obstet. ginecol.

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RESUMENEl carcinoma adenoideo quístico de la glándula de Bartolino (GB) es una entidad infrecuente, de crecimiento lento y comportamiento agresivo con alta recurrencia local y metástasis.Presentamos el caso de una paciente de 48 años, con antecedente de tratamiento quirúrgico de un absceso Bartolino derecho. La biopsia demostró un carcinoma adenoideo quístico (CAQ) de la GB, por lo que se realizó hemivulvectomía radical derecha y linfadenectomía inguinofemoral. El resultado de la biopsia mostró 4 ganglios positivos de 12 y margen lateral positivo a menos de 2 mm. Por lo que se realizó adyuvancia con radioterapia.La paciente no se presenta a su control y acude luego de tres años por dolor urente desde cadera izquierda hacia rodilla y cara lateral de la pierna y pie. Se realiza cintigrama óseo que muestra lesión osteoblástica sacroilíaca izquierda de 2 cm, por lo que se completó estudio de diseminación con tomografía computada de tórax, abdomen y pelvis con contraste que evidenció múltiples lesiones nodulares pulmonares bilaterales de distribución generalizada en parénquima central, periférico y subpleurales.Se deriva al Instituto Nacional del Tórax, completando estudio preoperatorio y se realizó una biopsia quirúrgica por video toracoscopía resecando un nódulo subpleural, el informe histológico señaló una metástasis de CAQ concordante con primario en GB.La paciente fue presentada en el comité oncológico y se indicó radioterapia paliativa a lesión sacroilíaca y control clínico ambulatorio. Ha evolucionado estable desde el punto de vista funcional pulmonar. PALABRAS CLAVE: Glándulas de Bartolino; carcinoma adenoideo quístico; metástasis neoplásicas ABSTRACTAdenoid cystic carcinoma of Bartholin glands (BG) is a rare, slow-growing but a highly aggressive tumor with remarkable capacity for local recurrence and distant metastasis. We present the case of a 48 year-old female patient with a history of surgical treatment for right Bartholin abscess. The biopsy showed a cystic adenoid carcinoma of the BG, which led to radical hemivulvectomy and inguinofemoral lymphadenectomy. The biopsy show inguinal lymph node metastasis on 4 of 12 lymph nodes and positive surgical resection margin. Adjuvant radiotherapy was applied.

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“…The local recurrence rate is approximately 25% (Abrao et al 1985), but local and distant recurrences are often late with a mean interval of 8 years (Copeland et al 1986b, Lelle et al 1994. They are usually treated with a wide local excision to the deep fascia and ipsilateral groin lymphadenectomy.…”

Section: Carcinomamentioning

confidence: 99%