Adenoid Cystic Carcinoma of Larynx

Abstract

Salivary gland tumours are rare tumours of larynx, hypopharynx and parapharyngeal space. Adenoid cystic carcinoma (AdCC) is the most common malignant salivary gland tumour of larynx. Subglottic region is the most common site followed by supraglottic region. AdCC usually involves elderly patients. Etiology of AdCC is mostly unknown. Clinically patient presents with dysphagia, cough, dyspnoea, hoarseness and rarely haemoptysis. Indirect laryngoscopy shows submucosal laryngeal mass. On CT scan, there is a submucosal mass, which may show extra-laryngeal extension. Histopathological examination shows epithelial and myoepithelial cells arranged in cribriform pattern, which may present with perineural invasion in the periphery of the lesion. Patients usually present in a later course of the disease. Tumour may present with pulmonary metastasis. The surgical approach depends on the tumour stage.