Adenoid Ciliostimulation in Children with Chronic Otitis Media

Andreoli, Steven; Schlosser, Rodney J.; Wang, Ling‐Feng; Mulligan, R. M.; Discolo, Christopher M.; White, David R.

doi:10.1177/0194599812462664

Cited by 6 publications

(2 citation statements)

References 25 publications

(47 reference statements)

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“…All patients had significantly lower ciliary activity compared to that found in normal guinea pigs. Andreoli et al found no significant difference in baseline CBF between children with AH + OSA, AH + chronic otitis media with effusion (EOM) and AH + recurrent episodes of acute otitis media (ROM). After stimulation with isoproterenol, patients with AH + EOM had significantly lower dynamic ciliary responses at 2 and 3 hours.…”

Section: Discussionmentioning

confidence: 99%

Ciliary beat frequency in children with adenoid hypertrophy

Marusiakova

Ďurdík

Jeseňák

et al. 2020

Pediatric Pulmonology

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Background Children with adenoid hypertrophy (AH) have impaired respiratory system defense mechanisms, such as mucociliary clearance. We hypothesized that AH negatively affects one of the most important aspects of mucociliary clearance—ciliary beat frequency (CBF) and that adenoidectomy could potentially restore this essential defence mechanism of the airways. This study evaluated the influence of AH and endoscopic adenoidectomy on the CBF of the nasal respiratory epithelium in children. Methods This prospective study included 64 children with confirmed AH aged 3 to 18 years and 43 age‐ and sex‐matched healthy controls. Nasal CBF was analyzed using a digital high‐speed video microscope and the software application Ciliary Analysis (NI LabVIEW). The preoperative adenoid size was assessed according to Cassano. Clinical symptoms of chronic rhinosinusitis were evaluated using the SNOT‐20 questionnaire. Results Children with AH had a median CBF of 5.35 ± 1.06 Hz. Six months after surgery, the median CBF was significantly higher (6.48 ± 0.88 Hz; P < .001) and reached the values of healthy children (6.37 ± 0.71 Hz; P = .512). The size of the adenoid tissue did not correlate with the CBF. No influence of age or gender on the CBF was found. After adenoidectomy, a significant reduction of the mean total SNOT‐20 score was recorded (P < .01). Conclusion Children with clinically symptomatic AH have impaired mucociliary clearance due to decreased nasal CBF. Removal of hypertrophic adenoid tissue normalizes the CBF and reduces the presence of clinical symptoms of rhinosinusitis.

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Section: Discussionmentioning

confidence: 99%

Ciliary beat frequency in children with adenoid hypertrophy

Marusiakova

Ďurdík

Jeseňák

et al. 2020

Pediatric Pulmonology

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“…In contrast, tonsillectomy alone may not be a helpful treatment for otitis media because tonsils are not anatomically associated with Eustachian tube function. Biofilms of bacteria in the adenoid have been reported to cause inflammation and mucosal edema, resulting in otitis media [5,16,17]. Paradise et al suggested that otitis media could be associated with infection not only in the nasopharynx, but also in the oropharynx based on their results that T&A was narrowly more efficacious against otitis media than adenoidectomy only [1].…”

Section: Discussionmentioning

confidence: 99%

The effect of tonsillectomy with adenoidectomy on medical services used in association with otitis media based on Korean national sample cohort data

Jeong

Choi

Nam

et al. 2020

Cost Eff Resour Alloc

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Background The effect of tonsillectomy with adenoidectomy (T&A) on otitis media has been investigated, but there have been no reports of the relationship between T&A and medical services used in association with otitis media. We investigated the effect of T&A on otitis media with regard to the number and cost of medical services used. Methods From the National Health Insurance Service National Sample Cohort data in Korea, we selected patients 7 years old or younger in 2002 who had T&A in 2005 while between the ages of three and ten. A control group was established matching the patient group with similar propensities of demographic characteristics. The number and cost of medical services used in association with otitis media were analyzed for 3 years before T&A through 8 years after T&A. Results The total number of patients was 1,338, with 227 in the T&A group and 1,111 in the non-T&A group. The number of medical services used was not significantly different between the T&A and non-T&A groups before and after surgery. The cost of medical services used was significantly higher in the T&A group than in the non-T&A group one year before surgery. The cost of medical services used was not significantly different between the two groups after surgery. Conclusions There were no significant differences between the T&A and non-T&A groups in the number and cost of medical services used in association with otitis media after surgery.

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Nasal Mucociliary Clearance in Adenoid Hypertrophy and Otitis Media with Effusion

Yazıcı

2015

Curr Allergy Asthma Rep

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Mucociliary clearance (MCC), which exists in many systems, is the first defensive mechanism of the human body. Nasal MCC has an important role in transporting the secretions of the nasal cavity and paranasal sinuses along with the trapped inhaled pathogens to the nasopharynx. Physiologic or pathologic situations that effect nasal MCC, such as temperature, humidity, nasal obstruction, allergic rhinitis, chronic infections, etc., lead to impaired MCC and related local or circumjacent system disorders. With this perspective, when a unified airway with a multiple disease principle is considered, investigating the relationship between adenoid hypertrophy (AH), otitis media with effusion (OME) and nasal MCC is logical. In this review, histological and physiologic properties of nasal MCC and its possible role involving pathologic situations such as AH and OME is discussed together with recent literature findings.

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Adenoid Ciliostimulation in Children with Chronic Otitis Media

Cited by 6 publications

References 25 publications

Ciliary beat frequency in children with adenoid hypertrophy

Ciliary beat frequency in children with adenoid hypertrophy

The effect of tonsillectomy with adenoidectomy on medical services used in association with otitis media based on Korean national sample cohort data

Nasal Mucociliary Clearance in Adenoid Hypertrophy and Otitis Media with Effusion

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