Nasal Mucociliary Clearance in Adenoid Hypertrophy and Otitis Media with Effusion

Abstract

Mucociliary clearance (MCC), which exists in many systems, is the first defensive mechanism of the human body. Nasal MCC has an important role in transporting the secretions of the nasal cavity and paranasal sinuses along with the trapped inhaled pathogens to the nasopharynx. Physiologic or pathologic situations that effect nasal MCC, such as temperature, humidity, nasal obstruction, allergic rhinitis, chronic infections, etc., lead to impaired MCC and related local or circumjacent system disorders. With this perspective, when a unified airway with a multiple disease principle is considered, investigating the relationship between adenoid hypertrophy (AH), otitis media with effusion (OME) and nasal MCC is logical. In this review, histological and physiologic properties of nasal MCC and its possible role involving pathologic situations such as AH and OME is discussed together with recent literature findings.

Risk factors for otitis media with effusion in children with adenoid hypertrophy

“…However, we did not observe any relationship between OME episodes and children who lived with pets. Nasal and nasopharyngeal pathologies may contribute to the formation of OME by affecting the upper airway 19 . Sinusitis, septal curvature, hypertrophy of concha choanal atresia, or stenosis can all affect air passage through the nasopharynx.…”

Allergy in pathogenesis of Eustachian Tube Dysfunction

“… 44 On the other hand, inflammatory mediators in the nasal mucosa may also directly spread to the ET, leading to ciliary clearance dysfunction and subsequent ETD. 45 Shi et al successfully constructed an animal model of OME by using OVA systemic sensitization and nasal stimulation method. From the tissue structure, they found that the mucosal tissue changes in the ET and the middle ear near the ET were the most obvious in allergic reactions.…”

The consequences of adenotomy for the children performed without a visual control: the strategy for the secondary surgical correction

“…Пирогова» Минздрава России, e-mail: radtsig_e@rsmu.ru ставанием в физическом и психомоторном развитии. При наличии вышеуказанной симптоматики и соответствующей эндоскопической/рентгенологической картины определяются показания к хирургическому вмешательству -аденотомии [4,5]. Аденотомия является самой частой операцией на лимфоглоточном кольце Вальдейера-Пирогова у детей, составляя до 84,3% хирургических вмешательств, выполняемых в ЛОР-стационарах [6].…”