Adenocarcinoma of the endometrium: Analysis of 256 cases with carcinoma limited to the uterine corpus

Hendrickson, Michael; Ross, John; Eifel, Patricia J.; Cox, Richard S.; Martínez, Álvaro; Kempson, Richard L.

doi:10.1016/0090-8258(82)90076-2

Cited by 135 publications

(56 citation statements)

References 27 publications

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“…Only the colonoscopic biopsies suggested the relationship between serous endometrial adenocarcinoma and the present. Data from the literature regarding the spread of endometrial neoplasms suggests that secondary determinations to the colon are very rare, and often associated with endometriosis or peritoneal dissemination, consequence of an advanced endometrial cancer [9,10]. The present case shows no signs of endometriosis (clinically and histologically), and hystopathological protocols excluded a peritoneal carcinomatosis in the first presentation which shows once again its particularity.…”

Section: Discussionmentioning

confidence: 66%

Multiple Colonic and Gastric Metastasis of Endometrial Adenocarcinoma - Case Report

Dobru¹,

Copotoiu²,

Silaghi³

et al. 2013

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MULTIPLE COLONIC AND GASTRIC METASTASIS OF ENDOMETRIAL ADENOCARCINOMA -CASE REPORT (Abstract): INTRODUCTION:In the gynecological malignancies endometrial adenocarcinoma is the second most common, giving early hematogenous and lymphatic metastasis to the lungs, brain and bones. CASE REPORT: We present the case of a 71 year old patient who underwent surgery two years ago for endometrial adenocarcinoma and followed postoperatively multimodal oncological treatment. The patient was admitted in January 2013 in the First Surgery Clinic of the Emergency Clinical County Hospital Târgu Mureş, Romania, for chronic anemia, consumptive disease signs and subocclusive syndrome. The preoperative exams (upper and lower gastrointestinal endoscopy, thoracoabdominal computed tomography and ultrasound) found a tumor invading right, transverse and sigmoid colon as well as gastric antrum and spleen. A subtotal colectomy with ileo-rectal anastomosis was then performed associated with distal gastrectomy and splenectomy. The histopathological exams revealed gastric and colonic metastasis from the endometrial serous cancer operated two years ago. The postoperative evolution was uneventful. CONCLUSIONS: Endometrial cancer can metastasize to the colon and stomach even without the presence of endometriosis. Multivisceral resections and preoperative exams of the digestive tract are justified in terms of subjective complaints of an occlusive simptomatology.

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Section: Discussionmentioning

confidence: 66%

Multiple Colonic and Gastric Metastasis of Endometrial Adenocarcinoma - Case Report

Dobru¹,

Copotoiu²,

Silaghi³

et al. 2013

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“…Tümörün davranışı açısından klinisyene çok fazla fikir vermeyen endometrium adeno ca tanısı verilirken histomorfolojik tiplendirmenin yapılmasının önemli olduğunu düşünmekteyiz. Özellikle müsinöz adeno ca tanısı verilmeden önce bir çok literatürde bildirildiği gibi vakalara müsin histokimyası yapılmalıdır (16,18). Vakalara uygulanan müsin histokimyası sonucu 29 vakada fokal ve diffüz boyanma izlenmiştir.…”

Section: Discussionunclassified

“…Histokimyasal yöntemlerin yardımıyla yeniden değerlendirmeye alınan vakalar Philips 1991 sınıfla-masına göre klasifiye edimiş ve tümörlerin gradelemesinde nükleer gradeleme ve FİGO gradelemesi birlikte kullanılmıştır (16,17,18) Bu her iki sisteme göre ; minimal nükleus atipisi ve yaygın tübüler yapılar içeren tümörler Grade 1 (şekil 1), orta derecede nükleus atipisi ve %50 solid alan içeren tümörler Grade 2 (şekil 2), belirgin nükleus atipisi ve %50 den fazla solid alan içeren tümörler Grade 3 olarak değerlendirilmiştir (şe-kil 3).…”

Section: Materyal Ve Metodunclassified

“…Vakaların boyanma şiddetleri (+) hafif, (++) orta şiddet-te,(+++) şiddetli boyanma şeklinde; boyanma yaygın-lığı açısından ise (+) fokal, (++) bir çok alanda küçük odaklar halinde, (+++) diffüz boyanma şeklinde değerlendirilmiştir.Bu değerlendirmeye göre yapılan incelemede diffüz şekilde ve (+++) şiddetli boyanma gösteren vakalara müsinöz adeno ca tanısı verilmiştir (16,18). riye kalan 5 vakanın hem küretaj hemde histerektomi materyallerinde boyanma diffüz olarak gözlenmiştir.…”

Section: şEkil 2 Hande X 100unclassified

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Endometri̇um Adenokanseri̇: 50 Vakanin Hi̇stoloji̇k Ve Hi̇stoki̇myasal Değerlendi̇rmesi̇

SERTÇELİK¹

1997

Ankara Üniversitesi Tıp Fakültesi Mecmuası

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“…It was more significant than histologic type. Grading of the tumors incorporated characteristics of cytoplasmic and nuclear size, variability, and atypicality, and not pattern of growth alone [6]. Less than one-half of the patients had well-differentiated lesions while one-fourth of the cases were poorly differentiated ( Table 2).…”

Section: General Observationsmentioning

confidence: 99%

Radiotherapeutic alternatives to standard management of adenocarcinoma of the endometrium

Andersen

Peters

Fechner

et al. 1983

Gynecologic Oncology

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Adenocarcinoma of the endometrium: Analysis of 256 cases with carcinoma limited to the uterine corpus

Cited by 135 publications

References 27 publications

Multiple Colonic and Gastric Metastasis of Endometrial Adenocarcinoma - Case Report

Multiple Colonic and Gastric Metastasis of Endometrial Adenocarcinoma - Case Report

Endometri̇um Adenokanseri̇: 50 Vakanin Hi̇stoloji̇k Ve Hi̇stoki̇myasal Değerlendi̇rmesi̇

Radiotherapeutic alternatives to standard management of adenocarcinoma of the endometrium

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