Additive prognostic value of high baseline coronary flow velocity to ejection fraction during resting echocardiography: 3-year prospective study

Zagatina, Angela; Guseva, O. A.; Калинина, Е. П.; Rigo, Fausto; Čaprnda, Martin; Masan, Jan; Gazdíková, Katarína; Firment, Peter; Ullrich, David; Gašpar, Ľudovít; Kružliak, Peter; Шматов, Д. В.

doi:10.1080/00015385.2021.2013004

Cited by 7 publications

(1 citation statement)

References 24 publications

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“…However, recently emphasis was placed on the importance of resting CFV in presence of angiographically normal coronary arteries, since a high value may identify a worse prognosis, possibly due to myocardialcoronary mismatch for excessive myocardial oxygen demand, or primary coronary small vessel autoregulatory defect [9]. This situation is different from the pattern of a high proximal-flow with reduced distal-LAD flow, which is a specific sign of proximal-LAD stenosis and requires a mapping of all sites [10,11]. Another important issue suggests the importance of mapping preliminarily the three different sites of LAD.…”

Section: The Importance Of Resting Cfvmentioning

confidence: 99%

Normal physiologic coronary flow velocity gradient across the left anterior descending artery in healthy asymptomatic subjects

Rigo,

Spadotto,

Fattore

et al. 2023

Explor Cardiol

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Aim: Coronary flow velocity (CFV) can be obtained with transthoracic echocardiography (TTE) in the left anterior descending coronary artery (LAD). The physiologic flow velocity gradient across the different segments of LAD has not been established. This study aims to assess the normal values of resting CFV in proximal, mid, and distal LAD. Methods: In a single center, prospective, observational study design, TTE was attempted on 110 consecutive, asymptomatic middle-aged subjects (age = 55 years, 46% males) with a low likelihood of coronary artery disease (< 5%). Resting CFV in the LAD was assessed with high-end machines, dedicated coronary pre-set, and high-frequency transducers by pulsed-wave Doppler under color-Doppler guidance in the proximal, mid, and distal segments. Results: The technical success rate for CFV imaging was lowest for the proximal (101/110, 92%), intermediate for mid (106/110, 96%), and highest for the distal segment (108/110, 98%). All 3 segments were interpretable in 101 subjects. CFV was highest in proximal segments (38.6 cm/s ± 3.9 cm/s), intermediate in mid segments (34.3 cm/s ± 6.04 cm/s, P < 0.01 vs. proximal), and lowest in distal segments (28.1 cm/s ± 1.7 cm/s, P < 0.01 vs. proximal and vs. mid). Conclusions: A resting evaluation of CFV-LAD can be obtained by TTE in the large majority of consecutive subjects referred to the echocardiography laboratory. Feasibility is highest for distal and lowest for proximal-LAD segments. There is a clear physiologic gradient of CFV with decreasing values, of about 10% for each step, going from proximal to mid and distal segments of LAD. When resting CFV is considered, the site of the sampling is important to obtain comparable and physiologically meaningful data.

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Section: The Importance Of Resting Cfvmentioning

confidence: 99%