Adaptation and validation of the Pediatric Asthma Quality of Life Questionnaire (PAQLQ) in Brazilian asthmatic children and adolescents

Scala, Cíntia Sayuri Kurokawa La; Naspitz, Charles K.; Solé, Dírceu

doi:10.2223/jped.1283

Cited by 32 publications

(31 citation statements)

References 25 publications

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“…Correlation of the score of PAQLQ in relation to therapy with ICS-fluticason propionat showed improvement in PAQLQ scores in all domains, as overall score after initiation of the therapy. It has been expected, since with the therapy, we achieved a better control of the disease, and also a better QL in these children, which has been confirmed in other studies [15][16][17][18]. Correlation between PAQLQ score and clinical parametars (asthma diary, FEV1, PEF, CSS), showed statistical significance with activities and symptoms domains and overall QL score, except for the domain of emotions.…”

Section: Discussionsupporting

confidence: 80%

Quality of Life in Children with Asthma as a Marker of Clinical Stability

Cvejoska-Cholakovska¹,

Vlaski²,

Velic-Stefanovska³

2014

Macedonian Medical Review

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Introduction. In order to improve asthma control, in the last decades an emphasis has been put on the assessment of quality of life (QL). The aim of the study was to assess the role of the Pediatric Asthma Quality of Life Questionnaire (PAQLQ) in order to assess the QL as a marker of clinical stability in asthmatic children. Methods. A total of 64 asthmatic children aged 7-17 years treated in an outpatient/hospital facility within the University Children's Hospital in Skopje during 2 years were investigated. The children were assessed 3 times during a period of 3 months. To assess the asthma control the Clinical Stability Score (CSS) was used, and for the assessment of the QL the Macedonian version of the PAQLQ from Elizabeth Juniper was used, consisting of 23 questions organized into three domains: symptoms, activities, and emotions. The data were statistically analyzed using Statistica for Windows, version 7.0 and SPSS 14.Results. An increase in the average values of the PAQLQ scores was established, which means better control of asthma by the end of the 3-month follow-up. There was no statistically significant difference in the QL changes and the age of asthmatic children regarding all three domains and the overall score. Better PAQLQ scores were detected in children with better CSS. A significant improvement of all the PAQLQ scores in the case of beginning the inhaled corticosteroid therapy during the study was found. According to CSS, all of the children were classified as stable (good QL) at the end of the study compared to 78% stability at the beginning of the study. Conclusions. The Macedonian version of the PAQLQ can be used for assessment of the effects of anti-inflammatory therapy and for attainment of complete asthma control in children between 7 and 17 years of age.

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Section: Discussionsupporting

confidence: 80%

Quality of Life in Children with Asthma as a Marker of Clinical Stability

Cvejoska-Cholakovska¹,

Vlaski²,

Velic-Stefanovska³

2014

Macedonian Medical Review

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“…A PubMed database search (March of 2009) for PAQLQ validation studies rendered 13 articles, 8 of which were cultural validation studies. (19,(21)(22)(23)(24)(25)(26)(27) Of those, there were two different reports of the validation of the Spanish-language version and one regarding the independent Brazilian version previously mentioned. However, among those studies, diverse methodologies were used to assess the properties.…”

Section: Resultsmentioning

confidence: 99%

“…(19) Although there were some methodological objections, (20) the authors certainly made a great investment of time and resources to develop a thorough validation process starting from zero. However, the resulting version is not available and would not be applicable, since the original author of the PAQLQ allows the use only of MAPI versions.…”

Section: Discussionmentioning

confidence: 99%

Versão brasileira do Paediatric Asthma Quality of Life Questionnaire: validação de campo

et al. 2010

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Objective: To assess the psychometric properties of the official Brazilian Portuguese-language version of the Paediatric Asthma Quality of Life Questionnaire (PAQLQ) in a representative group of Brazilian children and adolescents with asthma. Methods: A total of 125 individuals with asthma, aged 8-17 years and being monitored at a pediatric pulmonology outpatient clinic in the city of Porto Alegre, Brazil, completed the PAQLQ. Validity was assessed by means of convergent validity (correlation between PAQLQ domains and those of the Pediatric Quality of Life Inventory (PedsQL) 4.0. Reliability was assessed by determining internal consistency (Cronbach's alpha coefficient), reproducibility (intraclass correlation coefficient), sensitivity to change (effect size), and discriminatory power (floor/ceiling effects). Results: The mean age was 11 years, and 75 (60%) of the participants were male. The mean PAQLQ total score was 5.1, with floor/ceiling effects < 10%. Correlations between PAQLQ domains and the PedsQL 4.0 domains were acceptable (r = 0.37-0.40). The Cronbach's alpha coefficient for the total score was 0.93, ranging from 0.72 to 0.88 for the domains. The overall effect size was 0.60 (range: 0.45-0.60), whereas the overall intraclass correlation coefficient was 0.80 (range: 0.66-0.79). Conclusions: The official Brazilian Portugueselanguage version of the PAQLQ showed good psychometric performance, confirming its cultural adequacy for use in Brazil.

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“…The assessment of asthma control and quality of life were performed using the Asthma Control Questionary-ACQ [24] and Pediatric Asthma Quality of Life Questionnaire-PAQLQ [25], respectively, both translated and culturally adapted to the Brazilian population [26, 27]. …”

Section: Methodsmentioning

confidence: 99%

Vascular function in asthmatic children and adolescents

et al. 2017

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BackgroundEpidemiological studies have demonstrated an increased incidence of cardiovascular events in patients with bronchial asthma, but little is known about the relationship between asthma and vascular function. The purpose of this study was to evaluate endothelial function and arterial stiffness in children and adolescents with asthma.MethodsA cross-sectional controlled study was designed. Measurements of endothelial function and arterial stiffness in asthmatic (13.6 ± 0.6 years) and control groups (14.9 ± 0.7 years) were taken by the non-invasive peripheral arterial tonometry (EndoPAT2000) determined by using the natural logarithm of the reactive hyperemia index (LnRHI) and the augmentation index (AIx@75%), respectively. Patients with asthma were also administered two questionnaires to evaluate asthma control and quality of life. Exercise functional capacity was evaluated using the Shuttle Walking Test (SWT). Only male participants were included in the present study.ResultsLnRHI and the walked distance during the SWT were similar between groups (p = 0.23 and p = 0.50, respectively). AIx@75% was significantly higher in the asthmatic group (-7.75 ± 1.7) compared to the control group (-15.25 ± 1.8), p < 0.04. In the control group, the LnRHI correlated positively with baseline systolic blood pressure (r = 0.53, p = 0.02) and mean arterial pressure (r = 0.50, p = 0.03), age (r = 0.61, p = 0.007), weight (r = 0.63, p = 0.004) and height (r = 0.56, p = 0.015). Besides that LnRHI correlated with FVC (r = 0.69, p = 0.002), FEV1, (r = 0.53, p = 0.03) and negatively with Tiffeneau index (FEV1/FVC%, r = −0.49 p = 0.04). The LnRHI of the asthmatic group did not correlate with the different variables evaluated.ConclusionThe increased AIx@75% without changes in LnRHI in asthmatic patients could mean that an early detection of vascular impairment may precede endothelial dysfunction, and that different mechanisms may contribute to the pathogenesis and progression of cardiovascular events in this population. A large prospective and randomized controlled study should be done to evaluate the physiopathological mechanisms underlying the association between arterial stiffness and asthma.Electronic supplementary materialThe online version of this article (doi:10.1186/s12931-016-0488-3) contains supplementary material, which is available to authorized users.

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Adaptation and validation of the Pediatric Asthma Quality of Life Questionnaire (PAQLQ) in Brazilian asthmatic children and adolescents

Cited by 32 publications

References 25 publications

Quality of Life in Children with Asthma as a Marker of Clinical Stability

Quality of Life in Children with Asthma as a Marker of Clinical Stability

Versão brasileira do Paediatric Asthma Quality of Life Questionnaire: validação de campo

Vascular function in asthmatic children and adolescents

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