Acylated flavonol glycosides from Eugenia jambolana leaves

Mahmoud, Ibrahim I.; Marzouk, Mohamed; Moharram, Fatma A.; Elgindi, Mohamed R.; Hassan, A

doi:10.1016/s0031-9422(01)00365-x

Cited by 136 publications

(109 citation statements)

References 13 publications

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“…We extended the previous observation that SC leaf extracts contain flavonoids (23,27). Ramirez and Roa Jr. (28) showed a correlation between the anti-inflammatory activity and the content of total phenolic compounds in the extracts of SC.…”

Section: Discussionsupporting

confidence: 59%

“…The presence of polyphenol, gallic acid, ellagic acid derivatives (22,23), tannins (24,25), and glycosylated flavonoids (23,26,27) has been reported in Syzygium species. We extended the previous observation that SC leaf extracts contain flavonoids (23,27).…”

Section: Discussionmentioning

confidence: 99%

“…Some isolated flavonoids possess anti-inflammatory (37), antiallergic (38) and analgesic (39) activities; however, few flavonoids from SC leaves (23,27) and flowers have been isolated or identified (40).…”

Section: Discussionmentioning

confidence: 99%

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Pharmacological study of anti-allergic activity of Syzygium cumini (L.) Skeels

Brito

Lima

Ramos

et al. 2007

Braz J Med Biol Res

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Myrtaceae is a plant family widely used in folk medicine and Syzygium and Eugenia are among the most important genera. We investigated the anti-allergic properties of an aqueous leaf extract of Syzygium cumini (L.) Skeels (SC). HPLC analysis revealed that hydrolyzable tannins and flavonoids are the major components of the extract. Oral administration of SC (25-100 mg/kg) in Swiss mice (20-25 g; N = 7/group) inhibited paw edema induced by compound 48/80 (50% inhibition, 100 mg/kg; P ≤ 0.05) and, to a lesser extent, the allergic paw edema (23% inhibition, 100 mg/kg; P ≤ 0.05). SC treatment also inhibited the edema induced by histamine (58% inhibition; P ≤ 0.05) and 5-HT (52% inhibition; P ≤ 0.05) but had no effect on plateletaggregating factor-induced paw edema. SC prevented mast cell degranulation and the consequent histamine release in Wistar rat (180-200 g; N = 7/group) peritoneal mast cells (50% inhibition, 1 µg/mL; P ≤ 0.05) induced by compound 48/80. Pre-treatment of BALB/c mice (18-20 g; N = 7/group) with 100 mg/kg of the extract significantly inhibited eosinophil accumulation in allergic pleurisy (from 7.662 ± 1.524 to 1.89 ± 0.336 x 10 6 /cavity; P ≤ 0.001). This effect was related to the inhibition of IL-5 (from 70.9 ± 25.2 to 12.05 ± 7.165 pg/mL) and CCL11/eotaxin levels (from 60.4 ± 8.54 to 32.8 ± 8.4 ng/mL) in pleural lavage fluid, using ELISA. These findings demonstrate an anti-allergic effect of SC, and indicate that its anti-edematogenic effect is due to the inhibition of mast cell degranulation and of histamine and serotonin effects, whereas the inhibition of eosinophil accumulation in the allergic pleurisy model is probably due to an impairment of CCL11/eotaxin and IL-5 production.

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Section: Discussionsupporting

confidence: 59%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Pharmacological study of anti-allergic activity of Syzygium cumini (L.) Skeels

Brito

Lima

Ramos

et al. 2007

Braz J Med Biol Res

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“…Algumas espécies pertencentes ao gênero Eugenia apresentam atividade anti-inflamatória, analgésica, antipirética, antifúngica, sendo usadas no tratamento de úlceras peptídicas (Kuskoski et al, 2003;Mahmoud et al, 2001). Além disso, muitas espécies do gênero são relatadas como plantas ricas em polifenóis derivados de Tabela 3.…”

Section: /10unclassified

“…Uso ácido gálico e elágico, taninos e flavonóides glicosilados (Mahmoud et al, 2001), os quais podem ser utilizados na indústria farmacêutica.…”

Section: Espéciesunclassified

Myrtaceae na Bacia do Rio Caveiras: Características Ecológicas e Usos Não Madeireiros

et al. 2016

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RESUMOObjetivou-se descrever o padrão florístico-estrutural, as características ecológicas e os potenciais das Myrtaceae na bacia hidrográfica do Rio Caveiras. As comunidades de Myrtaceae estudadas localizam-se no Planalto Sul Catarinense, Lages, São José do Cerrito e Urupema. Foram instaladas quatro blocos por município, totalizando 30 mil m 2 de área amostral, nos quais todos os espécimes de Myrtaceae com diâmetro à altura do peito (DAP) ≥ 5 cm foram amostrados. A estrutura da comunidade de Myrtaceae foi avaliada pelos descritores fitossociológicos e a suficiência amostral foi verificada utilizando-se o método de rarefação. As abordagens ecológicas e indicações de uso não madeireiro basearam-se em bibliografia especializada e base de dados científicos. Foram amostrados 1.480 exemplares de Myrtaceae pertencentes a 21 espécies e 11 gêneros. As espécies mais abundantes foram Myrceugenia euosma, Siphoneugena reitzii e Myrcia palustris, as quais representaram mais de 50% da estrutura da comunidade. Quanto à classificação ecológica, destacou-se o grupo das secundárias iniciais (57%). As espécies amostradas são indicadas para restauração de áreas alteradas, usos ornamentais (100%) e fitoterápicos (60%). Apesar da representatividade e potencialidades das Myrtaceae, ainda são necessárias pesquisas para embasar a conservação via plano de manejo.Palavras-chave: classificação ecológica, restauração de áreas alteradas, uso fitoterápico. Myrtaceae in the Caveiras River Basin: Ecological Characteristics and Non-timber Uses ABSTRACTThis study aimed to describe the floristic-structural pattern, ecological characteristics and potentials of Myrtaceae in the Caveiras River Basin. The studied Myrtaceae communities are localized in Santa Catarina Southern Plateau -municipalities of Lages, São José do Cerrito and Urupema. Four sampling units were installed in each municipality, totaling a sampling area of 30,000 m 2 . All Myrtaceae individuals with DBH ≥ 5 cm were surveyed within the sampling units. The Myrtaceae community structure was assessed through phytosociological descriptors and the sampling sufficiency was verified using the rarefaction method. The ecological approach, as well as the indication of non-timber use of Myrtaceae resources was inferred from a specialized bibliography and scientific database. 1,480 Myrtaceae individuals were sampled, totaling 21 species and 11 genera. The most abundant species were Myrceugenia euosma, Siphoneugena reitzii and Myrcia palustris, which represent more than 50% of the community structure. Regarding the ecological classification, the late secondary group was the most expressive (57%). The sampled

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Phytochemical Principles in the Traditional Indian System of Medicine used for the Management of Metabolic Syndrome

Rizvi

2013

Metabolic Syndrome and Neurological Disorders

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Acylated flavonol glycosides from Eugenia jambolana leaves

Cited by 136 publications

References 13 publications

Pharmacological study of anti-allergic activity of Syzygium cumini (L.) Skeels

Pharmacological study of anti-allergic activity of Syzygium cumini (L.) Skeels

Myrtaceae na Bacia do Rio Caveiras: Características Ecológicas e Usos Não Madeireiros

Phytochemical Principles in the Traditional Indian System of Medicine used for the Management of Metabolic Syndrome

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