Acute visceral cysticercosis by <i>Taenia hydatigena</i> in lambs and treatment with praziquantel

Scala, Antonio; Urrai, Giovanni; Varcasia, Antonio; Nicolussi, Paola; Mulas, M.; Goddi, Lucia; Pipia, Anna Paola; Sanna, G.; Genchi, Marco; Bandino, Ennio

doi:10.1017/s0022149x14000601

Cited by 35 publications

(30 citation statements)

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“…The tapeworm T. hydatigena uses canids (primarily dogs) as definitive hosts. The metacestode larval stage of T. hydatigena infects mostly domestic animals such as goats, sheep and pigs, resulting in cysticercosis; an infection of veterinary importance that causes huge economic loses especially in livestock production as a result of mortality [1], condemnation of infected organs and carcasses, and the financial cost of diagnosis and inspection [2–5].…”

Section: Introductionmentioning

confidence: 99%

First molecular description, phylogeny and genetic variation of Taenia hydatigena from Nigerian sheep and goats based on three mitochondrial genes

et al. 2019

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BackgroundCysticercosis caused by the metacestode larval stage of Taenia hydatigena is a disease of veterinary and economic importance. A considerable level of genetic variation among isolates of different intermediate hosts and locations has been documented. Generally, data on the genetic population structure of T. hydatigena is scanty and lacking in Nigeria. Meanwhile, similar findings in other cestodes like Echinococcus spp. have been found to be of epidemiological importance. Our aim, therefore, was to characterize and compare the genetic diversity of T. hydatigena population in Nigeria based on three mitochondrial DNA markers as well as to assess the phylogenetic relationship with populations from other geographical regions.MethodsIn the present study, we described the genetic variation and diversity of T. hydatigena isolates from Nigerian sheep and goats using three full-length mitochondrial genes: the cytochrome c oxidase subunit 1 (cox1), NADH dehydrogenase subunit 1 (nad1), and NADH dehydrogenase subunit 5 (nad5).ResultsThe median-joining network of concatenated cox1-nad1-nad5 sequences indicated that T. hydatigena metacestodes of sheep origin were genetically distinct from those obtained in goats and this was supported by high FST values of nad1, cox1, and concatenated cox1-nad1-nad5 sequences. Genetic variation was also found to be higher in isolates from goats than from sheep.ConclusionsTo the best of our knowledge, the present study described the genetic variation of T. hydatigena population for the first time in Nigeria using full-length mitochondrial genes and suggests the existence of host-specific variants. The population indices of the different DNA markers suggest that analysis of long mitochondrial DNA fragments may provide more information on the molecular ecology of T. hydatigena. We recommend that future studies employ long mitochondrial DNA sequence in order to provide reliable data that would explain the extent of genetic variation in different hosts/locations and the biological and epidemiological significance.

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Section: Introductionmentioning

confidence: 99%

First molecular description, phylogeny and genetic variation of Taenia hydatigena from Nigerian sheep and goats based on three mitochondrial genes

et al. 2019

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“…In high infections, mortality may occurs, as described by Scala et al (2016) in central Sardinia, Italy, where an acute outbreak of T. hydatigena cysticercosis occurred, causing mortality in 5 of 21 (23.8%) female lambs. In Greek slaughtered sheep, the infection level due to C. tenuicollis was 29.4% (CHRISTODOULOPOULOS et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

Prevalence and risk factors for Cysticercus tenuicollis in goats and sheep in Paraíba, northeastern Brazil

Morais

Vilela

Feitosa

et al. 2017

Rev. Bras. Parasitol. Vet.

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This study aimed to determine the prevalence and risk factors for C. tenuicollis among goats and sheep in slaughterhouses in Paraíba. 390 animals (195 goats and 195 sheep) in the municipalities of Patos and Esperança, Paraíba, Brazil, were inspected between February and May 2014. The prevalence of C. tenuicollis was 39% (76/195) in goats and 17.4% (34/195) in sheep. In both species, most of the cysticerci vesicles were located at the omentum and mesentery. The only risk factor found was extensive sheep farming. It can be concluded that C. tenuicollis is highly prevalent in small ruminants in Paraíba, being more prevalent in goats than in sheep. Extensively-reared sheep were twice as likely to develop infection by this parasite.Keywords: Goat and sheep farming, cestode, Taenia hydatigena. ResumoObjetivou-se determinar a prevalência e os fatores de riscos de C. tenuicollis em caprinos e ovinos nos matadouros da Paraíba. Foram inspecionados 390 animais (195 caprinos e 195 ovinos) nos municípios de Patos e Esperança, Paraíba, Brasil, no período de Fevereiro a Maio de 2014. A prevalência de C. tenuicollis em caprinos foi de 39% (76/195) e em ovinos de 17,4% (34/195). Os locais mais acometidos por C. tenuicollis nas duas espécies foram o omento e o mesentério. O único fator de risco encontrado foi a produção extensiva de ovinos. Pode-se concluir que é alta a prevalência de C. tenuicollis em pequenos ruminantes no Estado da Paraíba, sendo mais prevalente na espécie caprina; e que ovinos criados de forma extensiva apresentam duas vezes mais riscos de contrais a infecção por este parasita.Palavras-chave: Caprinovinocultura, cestódeo, Taenia hydatigena.

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“…For instance, the cestode Taenia krabbei might play a crucial role as intestinal parasite in European wolves 24 and is known to develop metacestodes in cardiac and skeletal muscles in intermediate hosts 24 25 . In contrast to T. krabbei , for which no human case of cysticercosis has been reported so far, other tapeworm species have a high zoonotic potential 26 and are responsible for several types of cysticercoses ( T. hydatigena ) 27 , coenuroses ( T. multiceps ) 28 , and echinococcoses ( E. multilocularis, E. granulosus ) 29 . In addition, nematodes and trematodes spread by carnivores are known to cause trichinellosis ( Trichinella spp.)…”

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Population expansion and individual age affect endoparasite richness and diversity in a recolonising large carnivore population

Lesniak

Heckmann

Heitlinger

et al. 2017

Sci Rep

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The recent recolonisation of the Central European lowland (CEL) by the grey wolf (Canis lupus) provides an excellent opportunity to study the effect of founder events on endoparasite diversity. Which role do prey and predator populations play in the re-establishment of endoparasite life cycles? Which intrinsic and extrinsic factors control individual endoparasite diversity in an expanding host population? In 53 individually known CEL wolves sampled in Germany, we revealed a community of four cestode, eight nematode, one trematode and 12 potential Sarcocystis species through molecular genetic techniques. Infections with zoonotic Echinococcus multilocularis, Trichinella britovi and T. spiralis occurred as single cases. Per capita endoparasite species richness and diversity significantly increased with population size and changed with age, whereas sex, microsatellite heterozygosity, and geographic origin had no effect. Tapeworm abundance (Taenia spp.) was significantly higher in immigrants than natives. Metacestode prevalence was slightly higher in ungulates from wolf territories than from control areas elsewhere. Even though alternative canid definitive hosts might also play a role within the investigated parasite life cycles, our findings indicate that (1) immigrated wolves increase parasite diversity in German packs, and (2) prevalence of wolf-associated parasites had declined during wolf absence and has now risen during recolonisation.

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Acute visceral cysticercosis by Taenia hydatigena in lambs and treatment with praziquantel

Cited by 35 publications

References 10 publications

First molecular description, phylogeny and genetic variation of Taenia hydatigena from Nigerian sheep and goats based on three mitochondrial genes

First molecular description, phylogeny and genetic variation of Taenia hydatigena from Nigerian sheep and goats based on three mitochondrial genes

Prevalence and risk factors for Cysticercus tenuicollis in goats and sheep in Paraíba, northeastern Brazil

Population expansion and individual age affect endoparasite richness and diversity in a recolonising large carnivore population

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