Acute urticaria with angioedema in the setting of coronavirus disease 2019

Adeliño, Raquel; Andrés-Cordón, Joan F.; Martínez, Cinthia Aracelis De La Cruz

doi:10.1016/j.jaip.2020.04.061

Cited by 16 publications

(19 citation statements)

References 5 publications

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“…All symptoms except cough improved after 2 days of methylprednisolone and diphenhydramine. Moreover, Adeliño and colleagues 7 reported a 30-year-old woman who developed acute urticaria and angioedema 11 days after the onset of COVID-19 respiratory symptoms. Those manifestations quickly resolved after she received 3 days of ebastine 10 mg.…”

Section: Discussionmentioning

confidence: 99%

Angioedema and urticaria in a COVID-19 patient: A case report and review of the literature

2020

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Section: Discussionmentioning

confidence: 99%

Angioedema and urticaria in a COVID-19 patient: A case report and review of the literature

2020

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“…Similarly, an extensive review of 997 patients from 9 different countries analyzed by Jia et al found that approximately 22% of patients had urticarial eruptions [4••]. Urticaria with or without angioedema in the setting of confirmed or highly suspected COVID-19 infection has been observed in several reports and case series [2,5,[39][40][41][42][43][44][45][46][47]. Similar to other viral infections, urticarial rash may precede or occur simultaneously with COVID-19 systemic manifestations (i.e., fever, cough) and last for several days [5,39,43,44,47,48].…”

Section: Urticaria and Angioedemamentioning

confidence: 99%

Cutaneous Manifestations in Adult Patients with COVID-19 and Dermatologic Conditions Related to the COVID-19 Pandemic in Health Care Workers

Mawhirt

Frankel

Diaz³

2020

Curr Allergy Asthma Rep

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Purpose of Review COVID-19 (coronavirus viral disease 2019), due to the novel SARS-CoV-2, may present with different types of cutaneous manifestations of varying pathophysiology. During the ongoing pandemic, publications reporting dermatologic findings in COVID-19 continue to emerge. Recent Findings Cutaneous vasculopathy and microthrombus-related changes including acral and sacral lesions, retiform purpura, livedo reticularis, and cutaneous vasculitis are notable findings in adult patients. Other exanthems include urticaria or angioedema, morbilliform/maculopapular exanthems, erythema multiforme, and vesicular eruptions. Increased recognition of these findings, especially those consistent with cutaneous microthrombi or vasculitis, is of particular importance. Additionally, occupational dermatologic disease related to extended personal protective equipment (PPE) use, such as skin damage and irritant or allergic contact dermatitis (ACD), represents another emerging problem amidst the pandemic. Summary In this review, we highlight the various cutaneous manifestations associated with COVID-19 in adult patients and occupational dermatitis in health care workers (HCWs) caring for this patient population. Keywords COVID-19. SARS-CoV-2. Cutaneous manifestations. Dermatologic. Rash. Contact dermatitis Abbreviations AAD American Academy of Dermatology ACD Allergic contact dermatitis ACE2 Angiotensin-converting enzyme 2 AD Atopic dermatitis AGEP Acute generalized exanthematous pustulosis ARDS Acute respiratory distress syndrome COVID-19 Coronarvirus viral disease 2019 CSSV Cutaneous small vessel vasculitis DIC Disseminated intravascular coagulation DiHS/DRESS Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms HCW Health care worker ICD Irritant contact dermatitis ITP Immune thrombocytopenic purpura PPE Personal protective equipment PT Patch test RT-PCR Reverse transcriptase polymerase chain reaction SARS-CoV-2 Severe acute respiratory distress syndrome coronavirus 2 SDRIFE Symmetrical drug-related intertriginous and flexural exanthema This article is part of the Topical Collection on Allergic Skin Diseases

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“…After eliminating the overlaps between the two search engines, we were left with 23 works investigating the relationships between SARS-CoV-2 infection and urticaria. Of these, 18 reported cases of urticaria in patients with SARS-CoV-2 infection [20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37]. Unfortunately, not all studies reported the characteristics of the patients studied (gender, age, timing, etc.)…”

Section: Resultsmentioning

confidence: 99%

Urticaria and coronavirus infection a lesson from SARS-CoV-2 pandemic

Allegra

Asero

Giovannetti

et al. 2021

Eur Ann Allergy Clin Immunol

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Urticaria is a condition involving both skin and mucosal tissues characterized by the presence of wheals and/or angioedema. The acute form has been related to allergic reactions to drugs or foods, interaction with chemicals, or infections. We reviewed the association of urticaria with coronavirus infections. This review was carried out by the use of two search engines for published original articles, employing two key terms correlated to urticaria and viruses: "urticaria" and one term linked to each virus. The research of the relationships between SARS-CoV-2 and urticaria produced 18 papers (including a total of 114 cases. Surprisingly, the search for cases of urticaria in patients with SARS-CoV or MERS produced no results. We tried to interpret this discrepancy and attempted to analyze the possible pathogenesis of urticaria lesions in SARS-CoV-2.

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Acute urticaria with angioedema in the setting of coronavirus disease 2019

Abstract: Conflicts of interest: The authors declare that they have no relevant conflicts of interest. Informed consent: The patient gave written informed consent for publication (both clinical information and images).

Cited by 16 publications

References 5 publications

Angioedema and urticaria in a COVID-19 patient: A case report and review of the literature

Angioedema and urticaria in a COVID-19 patient: A case report and review of the literature

Cutaneous Manifestations in Adult Patients with COVID-19 and Dermatologic Conditions Related to the COVID-19 Pandemic in Health Care Workers

Urticaria and coronavirus infection a lesson from SARS-CoV-2 pandemic

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