Acute toxicity of selenate and selenite and their impacts on oxidative status, efflux pump activity, cellular and genetic parameters in earthworm Eisenia andrei

Ečimović, Sandra; Velki, Mirna; Vuković, Rosemary; Čamagajevac, Ivna Štolfa; Petek, Anja; Bošnjaković, Rebeka; Grgić, Magdalena; Engelmann, Péter; Bodó, Kornélia; Filipović-Marijić, V.; Ivanković, Dušica; Erk, Marijana; Mijošek, Tatjana; Lončarić, Zdenko

doi:10.1016/j.chemosphere.2018.08.095

Cited by 43 publications

(13 citation statements)

References 58 publications

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“…These have high solubility, which is why they are commonly found in surface waters [10]. SeO 4 2− is the most prevalent, whereas SeO 3 2− is the most toxic [8,11] and the most reactive, while usually being found in mildly oxidising acidic environments [9,12]. However, the oxyanions are both highly bioavailable and readily bioaccumulate in the food chain [10,13].…”

Section: Introductionmentioning

confidence: 99%

Enterococcus spp. Cell-Free Extract: An Abiotic Route for Synthesis of Selenium Nanoparticles (SeNPs), Their Characterisation and Inhibition of Escherichia coli

2022

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Selenite (SeO32−), the most toxic and most reactive selenium (Se) oxyanion, can be reduced to elemental selenium (Se0) nanoparticles by a variety of bacteria, including Enterococcus spp. Previously, the orthodox view held that the reduction of SeO32− to Se0 by a wide range of bacteria was solely accomplished by biological processes; however, recent studies have shown that various bacterial strains secrete metal-reducing metabolites, thereby indirectly catalysing the reduction of these metal species. In the current study, selenium nanoparticles were synthesised from the abiotic reduction of selenite with the use of Enterococcus spp. cell-free extract. Once separated from the cell-free extract, the particles were analysed using Fourier-transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), Transmission electron microscopy (TEM) and a Zetasizer. The results revealed that the SeNPs were spherical in shape, containing both amorphous and crystalline properties, and the sizes with the highest frequency ranged close to 200 nm. Additionally, the obtained nanoparticles exhibited antimicrobial properties by directly inhibiting the viability of an E. coli bacterial strain. The results demonstrate not only the potential of abiotic production of SeNPs, but also the potential for these particles as microbial inhibitors in medical or similar fields.

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Section: Introductionmentioning

confidence: 99%

Enterococcus spp. Cell-Free Extract: An Abiotic Route for Synthesis of Selenium Nanoparticles (SeNPs), Their Characterisation and Inhibition of Escherichia coli

2022

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“…However, all these studies are not based on simulated in vivo digestion and do not reflect the real health risks of arsenic in medicinal earthworms. Arsenic in the earthworm must be dissolved in the gastrointestinal tract before it is absorbed into the blood, which may cause toxic effects ( Ečimović et al, 2018 ). Hence, it is necessary to reveal the bioaccessible arsenic (bAs) species in the earthworm.…”

Section: Introductionmentioning

confidence: 99%

Medicinal Earthworm: Speciation and Bioaccessibility of Arsenic and Its Potential Health Risks

Zan

et al. 2022

Front. Pharmacol.

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Arsenic in environmental health has caused public concerns all over the world. However, high levels of arsenic residues in medicinal animals have not received enough attention. Medicinal earthworms are consumed widely in China, but its arsenic potential health risks to humans are unknown. This work investigated the total concentration, bioaccessibility, and speciation of arsenic in earthworms by ICP-MS and HPLC-ICP-MS to evaluate its potential health risks to humans. Arsenic was found in all earthworms at concentrations ranging from 0.4 to 53.6 mg kg−1. The bioaccessibility of arsenic (bAs) varied significantly and ranged from 12.1 to 69.1%, with inorganic arsenic (iAs, including As(III) and As(V)) as the predominant species. Furthermore, a small amount of arsenobetaine (AB) was found. The estimated daily intake dose (EDI), hazard quotient (HQ), and carcinogenic risk (CR) of arsenic in most of the samples exceeded the safe threshold level. Results from this study indicated that the potential health risks by the consumption of earthworms may not be negligible. Herein, recommendations for the use of earthworms and regulatory recommendations for arsenic limit standards were proposed. This study reminds us that more control and monitoring of arsenic in medicinal animals should be carried out.

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“…El estudio del Se en las plantas y otros organismos, ha tomado mayor relevancia por los beneficios conocidos y aún por conocer, dependiendo de la fuente, dosificación y condiciones ambientales en que se haga uso de este micronutriente esencial (Ečimović et al, 2018;Garduño-Zepeda y Márquez-Quiroz, 2018). El objetivo de este estudio fue evaluar tres fuentes químicas de Se a diferentes concentraciones cada una, sobre las características morfológicas, físicas y químicas de la semilla en la variedad Pinto Saltillo de frijol (Phaseolus vulgaris L.) bajo condiciones controladas de malla-sombra.…”

Section: Introductionunclassified

EN PRENSA Efecto de la suplementación de Selenio en algunos atributos y contenido de minerales esenciales en la semilla de frijol (Phaseolus vulgaris L.) EN PRENSA

Azpilcueta-Pérez

Sandoval

Sánchez-Cohen

et al. 2022

rbio

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El objetivo de este estudio fue evaluar el efecto del Selenio en las características morfológicas, físicas, peso y contenido de minerales esenciales en la semilla del frijol (Phaseolus vulgaris L.). Se usó un diseño experimental en bloques completos al azar con siete repeticiones. Los tratamientos fueron tres formulaciones químicas de Selenio: selenito de sodio (Na2SeO3), dióxido de selenio (SeO2) y selenato de sodio (Na2SeO4) a tres concentraciones cada una: 5,10 y 20 mg L-1 más el testigo (sólo agua des-ionizada). La aplicación de 10 mg L-1 de Na2SeO3 mejoró la anchura y longitud del grano, con valores de 7.22 y 12.68 mm, respectivamente y la aplicación de 5 y 20 mg L-1 de SeO2, mejoró el espesor y diámetro del grano, con valores de 7.68 y 5.09 mm, respectivamente. Consecuentemente, el peso de 100 semillas, fue significativamente mayor cuando se suplementó 5 mg L-1 de Na2SeO3 o SeO2, con valores de 30 y 30.99 g, respectivamente. Las formulaciones Na2SeO3 y SeO2 a concentraciones de 5 mg L-1, mejoraron el radio aspecto, volumen y área superficial del grano. Finalmente, la aplicación de SeO2 y Na2SeO3 a concentraciones de 10 y 20 mg L-1,aumentaron moderadamente el contenido de Ca y Cu, respectivamente. Las formulaciones Na2SeO3 y SeO2 a dosis entre 5 a 20 mg L-1 fueron los más consistentes en mostrar un mejor efecto en mejorar los atributos dela semilla de frijol, respecto a la formulación Na2SeO4 en cualquiera de las formulaciones usadas en este estudio.

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Acute toxicity of selenate and selenite and their impacts on oxidative status, efflux pump activity, cellular and genetic parameters in earthworm Eisenia andrei

Cited by 43 publications

References 58 publications

Enterococcus spp. Cell-Free Extract: An Abiotic Route for Synthesis of Selenium Nanoparticles (SeNPs), Their Characterisation and Inhibition of Escherichia coli

Enterococcus spp. Cell-Free Extract: An Abiotic Route for Synthesis of Selenium Nanoparticles (SeNPs), Their Characterisation and Inhibition of Escherichia coli

Medicinal Earthworm: Speciation and Bioaccessibility of Arsenic and Its Potential Health Risks

EN PRENSA Efecto de la suplementación de Selenio en algunos atributos y contenido de minerales esenciales en la semilla de frijol (Phaseolus vulgaris L.) EN PRENSA

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