Acute physiological and performance responses to repeated sprints in varying degrees of hypoxia

Bowtell, Joanna L.; Cooke, Karl; Turner, Rachel; Mileva, Katya N.; Sumners, D

doi:10.1016/j.jsams.2013.05.016

Cited by 80 publications

(119 citation statements)

References 25 publications

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“…Although hypoxia has previously caused performance decrements during highintensity anaerobic exercise (2,3), the current data demonstrated no differences in performance during high-intensity resistance exercises in either moderate-level or high-level hypoxia. Furthermore, trends in force and power values across each set were consistent in all experimental conditions.…”

Section: Discussioncontrasting

confidence: 67%

“…Therefore, it is plausible that hypoxia-related central fatigue might impact on performance of high-intensity resistance exercise under systemic hypoxic conditions. Furthermore, hypoxia has been demonstrated to impair anaerobic performance during 15 s repeated sprints (15-45 s recovery between efforts) in elite female road cyclists (3), and to decrease peak speed during 6 s repeated sprints on a non-motorised treadmill (30 s recovery between efforts) in male athletes (2). Both repeat sprint activities and resistance exercise are characterised by repeated short-duration highintensity efforts that are fuelled largely by anaerobic metabolism.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Physical Performance During High-Intensity Resistance Exercise in Normoxic and Hypoxic Conditions

Scott¹,

Slattery

Sculley

et al. 2015

Journal of Strength and Conditioning Research

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This study aimed to determine whether different levels of hypoxia affect physical performance during high-intensity resistance exercise, or subsequent cardiovascular and perceptual responses. Twelve resistance-trained young men (age: 25.3 ± 4.3 yr; height: 179.0 ± 4.5 cm; body mass: 83.4 ± 9.1 kg) were tested for 1-repetition maximum (1RM) in the back squat and deadlift. Following this, participants completed three separate randomized trials of 5 x 5 repetitions at 80% 1RM, with 3 minutes rest between sets, in either normoxia, (NORM; fraction of inspired oxygen [F I O 2 ] = 0.21), moderate-level hypoxia (MH; F I O 2 = 0.16), or high-level hypoxia (HH; F I O 2 = 0.13) via a portable hypoxic unit. Peak and mean force and power variables were monitored during exercise. Arterial oxygen saturation (SpO 2 ), heart rate (HR), and rating of perceived exertion (RPE) were assessed immediately following each set.No differences in force or power variables were evident between conditions. Similar trends were evident in these variables across each set and across the exercise session in each condition. SpO 2 was lower in hypoxic conditions than in NORM, whereas HR was higher following sets performed in hypoxia. There were no differences between conditions in RPE.These results indicate that a hypoxic stimulus during high-intensity resistance exercise does not alter physical performance during repetitions and sets, or affect how strenuous exercise is perceived to be. This novel training strategy can be used without adversely affecting the physical training dose experienced, and may provide benefits over the equivalent training in normoxia.

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Section: Discussioncontrasting

confidence: 67%

Section: Introductionmentioning

confidence: 99%

Physical Performance During High-Intensity Resistance Exercise in Normoxic and Hypoxic Conditions

Scott¹,

Slattery

Sculley

et al. 2015

Journal of Strength and Conditioning Research

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“…The physiological effect of fatigue can be attributable to energy metabolism, metabolite accumulation, and muscle glycogen depletion, which are also associated with hypoxia (27). The enhancement of ATP levels in the serum and liver following 7-day administration may contribute, in part, to PHC-mediated fatigue recovery.…”

Section: Discussionmentioning

confidence: 99%

Investigations on the antifatigue and antihypoxic effects of Paecilomyces hepiali extract

Wang

Liu

et al. 2015

Molecular Medicine Reports

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Abstract. Paecilomyces hepiali, one of the most valuable and effective Chinese medicinal herbs, possesses potential antioxidant, immunomodulatory, antitumor and anti-inflammatory properties. The present study aimed to investigate the antifatigue and antihypoxic effects of Paecilomyces hepiali extract (PHC) in a mouse model. Using a rotating rod, forced swimming and running assessment, the antifatigue activity of PHC was determined. PHC administration for 7 days had no effect on mouse horizontal or vertical movement, indicating no neurotoxicity at the selected doses was observed. Using a normobaric hypoxia, sodium nitrite toxicosis and acute cerebral ischemia assessments, PHC was confirmed to possess antihypoxic effects. PHC treatment for 7 days significantly enhanced the serum and liver levels of adenosine triphosphate, superoxide dismutase and glutathione peroxidase, prior to and following 60 min of swimming. The levels of antioxidant-associated proteins in the livers of the mice were analyzed using western blotting. PHC effectively increased the expression levels of phosphorylated (p)-5'-monophosphate (AMP)-activated protein kinase (AMPK), p-protein kinase B (AKT) and p-mammalian target of rapamycin (mTOR). The results of the present study demonstrated that PHC efficiently enhanced endurance from fatigue and had antihypoxic effects through elevation of the antioxidant capacity in the serum and liver, at least in part through the AMPK and AKT/mTOR pathways. These results indicate the potential of this natural product as an antioxidant in the treatment of fatigue, hypoxia and their associated diseases.

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“…Exacerbated deoxygenation of skeletal muscle tissue in hypoxia has also been shown to increase reliance on glycolytic rather than aerobic energy production (Bowtell et al, 2014). Although it is not clear regarding the actual contributions of different systems to energy production during IHRT or RSH, research has demonstrated that short duration running performance can be maintained in hypoxia due to a shift toward anaerobic metabolism (Weyand et al, 1999).…”

Section: Impacts Of Hypoxia On Metabolic Processesmentioning

confidence: 99%

High-Intensity Exercise in Hypoxia: Is Increased Reliance on Anaerobic Metabolism Important?

Scott

Goods²,

Slattery

2016

Front. Physiol.

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Acute physiological and performance responses to repeated sprints in varying degrees of hypoxia

Cited by 80 publications

References 25 publications

Physical Performance During High-Intensity Resistance Exercise in Normoxic and Hypoxic Conditions

Physical Performance During High-Intensity Resistance Exercise in Normoxic and Hypoxic Conditions

Investigations on the antifatigue and antihypoxic effects of Paecilomyces hepiali extract

High-Intensity Exercise in Hypoxia: Is Increased Reliance on Anaerobic Metabolism Important?

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