Acute phase response and plasma carotenoid concentrations in older women: Findings from the nun study

Associations of plasma carotenoids with risk factors and biomarkers related to cardiovascular disease in middle-aged and older women

“…An inverse association between plasma carotenoids and inflammatory markers was reported previously among elderly nuns(37) and lung cancer patients. (38) In adults with acute inflammatory conditions such as tuberculosis(39) and pancreatitis,(40) there were transient decrease in serum carotenoids and increase in CRP level, which normalize with resolution of the illness.…”

Types of acute phase reactants and their importance in vaccination (Review)

“…The acute phase response is a spontaneous reaction triggered by disrupted homeostasis resulting from environmental disturbances (3). Acute phase reactions (APRs) usually stabilize quickly, after recovering from a disruption to homeostasis within a few days to weeks; however, APPs expression levels often remain elevated in long lasting infection and chronic disease states, such as cancer (4)(5)(6).…”

Effect of a tomato-rich diet on markers of cardiovascular disease risk in moderately overweight, disease-free, middle-aged adults: a randomized controlled trial

“…The relation between lycopene intake and CVD risk has recently been reviewed (4) and shows that a small majority of studies (57%) found an inverse relation between CVD risk markers and/or CVD incidence. High lycopene concentrations in blood and adipose tissue correlate with a reduction in CVD incidence (5)(6)(7)(8), and low concentrations are associated with early atherosclerosis (9) and elevated C-reactive protein concentrations (12,13). Low arterial intimal wall thickness associated with higher adipose tissue lycopene concentrations suggests a decreased risk of arterial occlusion (7,10,11).…”