Acute Phase Proteins: Ferritin and Ferritin Isoforms

Koorts, Alida Maria; Viljoen, Margaretha

doi:10.5772/20586

Cited by 2 publications

(1 citation statement)

References 170 publications

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“…Одновременно цитокины и липополисахариды стимулируют абсорбцию и удержание железа фагоцитами. Так, IL1, 6 и 10 усиливают продукцию ферритина [48]. IL10 активирует рецепторы к трансферрину [49].…”

Section: влияние перинатального дефицита железа на развитие когнитивнunclassified

The Role of Iron in the Pathogenesis of Autism Spectrum Disorders in Children

Kostina

2018

Vopr. sovr. pediatr.

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The review presents an analysis of the mechanisms of iron effect on the brain development. The importance of iron deficiency in the perinatal period is considered as a risk factor for the development of neuropsychiatric disorders in children with autism spectrum disorders (ASDs). Possible causes of sideropenia are discussed; data on haematological and biochemical parameters characterizing iron metabolism in children with ASDs are presented. The demand for studying the role of iron metabolism imbalance in the development of neuropsychiatric disorders in order to clarify pathogenetic mechanisms of ASDs and to determine methods for their correction is emphasized.

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Section: влияние перинатального дефицита железа на развитие когнитивнunclassified

The Role of Iron in the Pathogenesis of Autism Spectrum Disorders in Children

Kostina

2018

Vopr. sovr. pediatr.

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Iron Deficiency in Vegetarian and Omnivorous Individuals: Analysis of 1340 Individuals

et al. 2021

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The objective of this study was to evaluate the serum levels of ferritin and the prevalence of iron deficiency in vegan and omnivorous individuals by taking into account the presence of elements that cause an elevation of ferritin levels, such as increased homeostatic model assessment of insulin resistance (HOMA-IR), body mass index (BMI), and high-sensitivity C-reactive protein (hs-CRP) values. The parameters were evaluated in 1340 individuals, i.e., 422 men and 225 women who do not menstruate and 693 women who do menstruate, based on omnivorous or vegetarian eating habits. The progressive increase in BMI, HOMA-IR, and inflammation caused an elevation in ferritin concentration, regardless of the eating habits in the groups studied. In the overall sample, omnivores had a higher prevalence of obesity, higher ferritin levels, and a lower prevalence of iron deficiency (ferritin < 30 ng/mL). However, after the exclusion of individuals with inflammation (with overweight/obesity and elevated hs-CRP levels), the actual iron deficiency was assessed and was not higher among vegetarians, except in women with regular menstrual cycles. Our data show that nutritional status and inflammation levels affect ferritin levels and may interfere with the correct diagnosis of iron deficiency in both vegetarian and omnivorous individuals. Compared to vegetarians, women who do not menstruate and men had the same prevalence of iron deficiency when following an omnivorous diet.

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Acute Phase Proteins: Ferritin and Ferritin Isoforms

Cited by 2 publications

References 170 publications

The Role of Iron in the Pathogenesis of Autism Spectrum Disorders in Children

The Role of Iron in the Pathogenesis of Autism Spectrum Disorders in Children

Iron Deficiency in Vegetarian and Omnivorous Individuals: Analysis of 1340 Individuals

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