Acute Phase of Myocardial Infarction

Adgey, A. A. J.; Geddes, J S; Webb, S. W.; Allen, John D.; James, Richard G.G.; Zaidi, S A; Pantridge, J. F.

doi:10.1016/s0140-6736(71)90434-x

Cited by 209 publications

(23 citation statements)

References 28 publications

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“…15, 17 (3) The atrioventricular nodal artery that originates from the right coronary artery in 90% of patients and from the left circumflex artery in 10% of patients and supplies the atrioventricular node and also the left atrium directly and/or by anastomoses with other left atrial branches. [5][6][7][8][9][10][11][12][13][14][15][16][17][18] Early atrial fibrillation. Only seven of the 214 patients (3%) developed atrial fibrillation within 3 hr of the onset of chest pain.…”

Section: Methodsmentioning

confidence: 99%

Early atrial fibrillation during evolving myocardial infarction: a consequence of impaired left atrial perfusion.

Hod¹,

Lew²,

Keltai³

et al. 1987

Circulation

105

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Seven of 214 patients (3%) with acute myocardial infarction (120 inferior and 94 anterior) developed atrial fibrillation within 3 hr of the onset of chest pain. All seven patients had an inferior infarction and in all seven the left circumflex artery was occluded proximal to the origin of its left atrial circumflex branch. In five patients this occlusion was acute and was the cause of inferior infarction and in the remaining two patients the occlusion was old and the inferior infarction was due to an acute occlusion of the right coronary artery that also supplied extensive collaterals to the previously occluded left circumflex artery. All seven patients also had impaired perfusion to the atrioventricular nodal artery, as evidenced by total occlusion proximal to its origin or by stenosis proximal to its origin associated with second-or third-degree atrioventricular block. In contrast, early atrial fibrillation did not occur in any of the 18 patients with inferior myocardial infarction due to acute occlusion of the distal left circumflex artery or in any of the five patients with inferior infarction due to acute occlusion of the proximal left circumflex artery if perfusion to the atrioventricular nodal artery was not impaired. Early atrial fibrillation did not occur in any of the 90 patients with inferior infarction due to acute occlusion of the right coronary artery, including 12 patients with occlusion proximal to the sinus nodal artery, but without coexistent occlusion of the left circumflex artery. Our data indicate that early atrial fibrillation in acute myocardial infarction occurs when there is coexistent occlusion of the left circumflex artery proximal to the origin of its left atrial circumflex branch and impaired perfusion of the atrioventricular nodal artery. Since these two arteries both contribute to left atrial perfusion, our data suggest that acute left atrial ischemia is the pathophysiologic mechanism of early atrial fibrillation.Circulation 75, No. 1, 146-150, 1987. ATRIAL FIBRILLATION complicates acute myocardial infarction in about 20% of patients. It usually occurs later than 24 hr after the onset of infarction as a consequence of either pericarditis or heart failure.1 In contrast, atrial fibrillation during the early hours of myocardial infarction is rare`and its pathogenesis is poorly understood. The purpose of this study was to investigate the pathogenesis of atrial fibrillation in the early hours of an acute myocardial infarction in a population of patients who were admitted within 3 hr of the

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Section: Methodsmentioning

confidence: 99%

Early atrial fibrillation during evolving myocardial infarction: a consequence of impaired left atrial perfusion.

Hod¹,

Lew²,

Keltai³

et al. 1987

Circulation

105

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“…Cerca de 40% dessas mortes eram devidas a arritmias graves -fibrilação ventricular e assistolia -em pacientes sem insuficiência cardíaca grave ( Julian et al, 1964;Lown et al, 1967a). As arritmias precursoras dessas paradas cardíacas ocorrem, sobretudo, nas primeiras horas pós-infarto, um percentual pequeno ocorrendo após o primeiro dia da doença ( Julian et al, 1964;Lown et al, 1967a;Adgey et al, 1971). Parte da diferença da letalidade hospitalar entre cidades e países era atribuída a diferenças de delta tempo dos pacientes: quanto mais alto, maior era a mortalidade extra-hospitalar e menor era a incidência de arritmias e paradas cardíacas em pacientes internados (Lawrie et al, 1967;Christiansen et al, 1971).…”

Section: Conjunto Original (Eo)unclassified

Metodologia para a estimativa de padrões de qualidade: o caso do infarto agudo do miocárdio

1996

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“…This communication deals with these 88 patients (81 men and 7 women), all of whom fulfilled the criteria for indubitable infarction previously described (Adgey et al, 1968;Adgey et al, 1971). …”

Section: Introductionmentioning

confidence: 80%