Acute Pancreatitis and Gastroduodenal Intussusception Induced by an Underlying Gastric Gastrointestinal Stromal Tumor: A Case Report

Abstract

Gastrointestinal stromal tumors (GISTs) are rare tumors of the gastrointestinal system and comprise only 1% to 3% of all gastrointestinal tract tumors, with the majority of them arising in the stomach. In this report, we present the unique findings of a case of gastroduodenal intussusception caused by an underlying gastric GIST and complicated with severe acute pancreatitis.

Case report and literature review: patient with gastroduodenal intussusception due to the gastrointestinal stromal tumor of the lesser curvature of the gastric body

“…Reviewing the literature, patients with GIST and gastroduodenal intussusception most commonly presented with nonspecific symptoms of acute or intermittent abdominal pain with vomiting lasting from a day to several months (Table 1) [5–21]. Similar to our patient in some reports GI bleeding was noticed (Table 1) [9, 10, 13].…”

“…Most GIST arise from gastric wall (56%), followed by the small intestine and colon [4]. By authors best knowledge, GIST was described, as a leading point for gastroduodenal intussusception in only 17 cases (Table 1) [5–21].…”

“…By authors best knowledge, GIST was described, as a leading point for gastroduodenal intussusception in only 17 cases (Table 1) [5–21].…”

Gastroduodenal intussusception and pylorus obstruction induced by a c-KIT-negative gastric gastrointestinal stromal tumor: case report and review of the literature

“…Gastroduodenal intussusception, also known as ball valve syndrome, is an extremely rare event, which occurs when a gastric umor herniates into the duodenum and induces gastric obstruction. Ball valve syndrome is rare, although various etiologies like gastric adenoma, leiomyoma, lipoma, hamartoma inflammatory fibroid polyp, adenocarcinoma, and leiomyosarcoma can cause this pathology [1]. However, gastrointestinal stromal tumors (GISTs) are infrequently reported to cause gastroduodenal intussusception [2,3], especially in the cases with complete pylorus obstruction.…”

A Rare Cause of Acute Pancreatitis

“…This rare presentation is documented to be caused by both benign and malignant lesions, including hyperplastic and adenomatous polyp, adenocarcinoma, lipoma, leiomyoma, leiomyosarcoma, Brunner's gland hamartoma, and gastrointestinal stromal tumors. 1 Gastroduodenal intussusception induced by gastric tumor tends to arise in the distal part of the stomach, mainly in the antrum, and is less commonly seen in the body, fundus, and anastomosis. 1 Downward traction of the duodenal wall by the intussusceptum may have distorted and obstructed the ampulla of Vater.…”