Acute myelogenous leukaemia presenting as a conjunctival lesion and red eye

Bilateral epibulbar granulocytic sarcomas: a case of an 8-year-old girl with acute myeloid leukaemia

“…Each of the other reported cases were in adults, as were the cases of acute monocytic and acute myelomonocytic leukaemia with conjunctival disease [8]. Interestingly, all but one of the adult patients were noted to exhibit complete resolution of ocular infiltration and symptoms with chemotherapy or radiotherapy [3][4][5]8]. However, the majority died within 1 year, suggesting that a poor prognosis may be associated with conjunctival granulocytic sarcomas [2,8].…”

“…The underlying sclera, ciliary body, and uvea appeared normal. T tumour S sclera CB ciliary body kaemia and all were in adults with only one bilateral occurrence [3][4][5]8]. Only Zimmerman and Font, more than 30 years ago, described a paediatric case of bilateral nodular conjunctival infiltrates in AML, but a subtype was not specified [11].…”

Myeloid sarcoma presenting as an unusual limbal mass

“…Myeloid sarcoma most commonly involves skin, lymph nodes and bones 5. Ocular and adnexal involvement has been variably reported 6. In at least two prospective studies in medical literature, none of the patients with AML had leukaemic infiltrates involving the eye 7 8.…”

T-cell prolymphocytic leukemia presenting as red eye

“…However, conjunctival leukemic infiltration has been previously frequently described 6–8. Conjunctival leukemic infiltration was first published by Leber in 1878 49.…”

“…Review of the literature showed that conjunctival involvement may be a presenting sign of leukemia or signifies relapse of the disease 2–46–8…”