Acute mountain sickness and oxygen saturation

Sikri, Gaurav; Srinivasa, A B; Bhutani, Sourabh

doi:10.1007/s11325-016-1324-1

Cited by 3 publications

(2 citation statements)

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“…People who live at sea level for generations and those with a history of AMS or migraine are also reported to be at high risk for developing AMS [5]. Age, sex, smoking status and obesity have been associated with AMS in some but not all studies [5][6][7][8][9]. For example, younger subjects were found to be more susceptible to AMS [5,8].…”

Section: Introductionmentioning

confidence: 99%

Association between physiological responses after exercise at low altitude and acute mountain sickness upon ascent is sex-dependent

et al. 2020

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Background Acute mountain sickness (AMS) is the mildest form of acute altitude illnesses, and consists of non-specific symptoms when unacclimatized persons ascend to elevation of ≥2500 m. Risk factors of AMS include: the altitude, individual susceptibility, ascending rate and degree of pre-acclimatization. In the current study, we examined whether physiological response at low altitude could predict the development of AMS. Methods A total of 111 healthy adult healthy volunteers participated in this trial; and 99 (67 men and 32 women) completed the entire study protocol. Subjects were asked to complete a 9-min exercise program using a mechanically braked bicycle ergometer at low altitude (500 m). Heart rate, blood pressure (BP) and pulse oxygen saturation (SpO2) were recorded prior to and during the last minute of exercise. The ascent from 500 m to 4100 m was completed in 2 days. AMS was defined as ≥3 points in a 4-item Lake Louise Score, with at least one point from headache wat 6–8 h after the ascent. Results Among the 99 assessable subjects, 47 (23 men and 24 women) developed AMS at 4100 m. In comparison to the subjects without AMS, those who developed AMS had lower proportion of men (48.9% vs. 84.6%, P < 0.001), height (168.4 ± 5.9 vs. 171.3 ± 6.1 cm, P = 0.019), weight (62.0 ± 10.0 vs. 66.7 ± 8.6 kg, P = 0.014) and proportion of smokers (23.4% vs. 51.9%, P = 0.004). Multivariate regression analysis revealed the following independent risks for AMS: female sex (odds ratio (OR) =6.32, P < 0.001), SpO2 change upon exercise at low altitude (OR = 0.63, P = 0.002) and systolic BP change after the ascent (OR = 0.96, P = 0.029). Women had larger reduction in SpO2 after the ascent, higher AMS percentage and absolute AMS score. Larger reduction of SpO2 after exercise was associated with both AMS incidence (P = 0.001) and AMS score (P < 0.001) in men but not in women. Conclusions Larger SpO2 reduction after exercise at low altitude was an independent risk for AMS upon ascent. Such an association was more robust in men than in women. Trial registration Chinese Clinical Trial Registration, ChiCTR1900025728. Registered 6 September 2019.

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Section: Introductionmentioning

confidence: 99%

Association between physiological responses after exercise at low altitude and acute mountain sickness upon ascent is sex-dependent

et al. 2020

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“…(2) Selain itu, terdapat studi yang dilakukan pada tahun 2016 menyimpulkan bahwa kejadian AMS dapat terjadi karena pajanan mendadak terhadap ketinggian, biasanya di saat seseorang telah berada lebih dari 8000 kaki di atas permukaan laut. (3). Data publikasi dari Military Medical Research pada tahun 2019 oleh Murdoch et al menyebutkan angka prevalensi kejadian AMS yang cukup tinggi, yaitu sebesar 88.6% pada para pendaki di Nepal.…”

Section: Abstract Pendahuluanunclassified

Hubungan tingkat aktivitas fisik dengan acute mountain sickness pada pendaki gunung

Permatasari¹,

Sidarta

2021

J Biomedika Kesehat

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LATAR BELAKANGAcute mountain sickness (AMS) merupakan kelainan yang sering dialami oleh pendaki pemula di ketinggian lebih dari 2.500m. Menurut jurnal yang dikeluarkan oleh Military Medical Research pada tahun 2019, Murdoch mengemukakan bahwa prevalensi AMS sebesar 88.6%. Di Indonesia, masih sangat sedikit studi dan penelitian yang membahas AMS di kalangan pendaki gunung. Pada pendaki memiliki tingkat aktivitas fisik yang baik dapat mempermudah mereka dalam melakukan suatu perjalanan pendakian gunung. Tujuan penelitian ini adalah menilai hubungan tingkat aktivitas fisik dengan acute mountain sickness pada pendaki gunung. METODEPenelitian dilakukan pada bulan Februari-Juni 2021 di komunitas Mapala (mahasiswa pencinta alam), dan responden yang pernah mendaki gunung dengan menggunakan desain studi cross-sectional. Tingkat aktivitas fisik diukur menggunakan kuesioner GPAQ (Global Physical Activity Questionnaire) dan derajat kejadian acute mountain sickness diukur menggunakan kuesioner LLS (Lake Louise Acute Mountain Sickness Score). Analisis menggunakan uji Chi-square dengan tingkat kemaknaan p<0.05. HASILResponden pada penelitian ini didominasi oleh kelompok usia dari 19 sampai 39 tahun dengan variasi tingkat aktivitas fisik dari kategori sedang (50%) ke berat (40.7%). Seluruh responden mengalami kejadian AMS dari kategori ringan (73.7%) ke sedang (23.7%). Pada kelompok responden yang memiliki tingkat aktivitas fisik kategori tinggi maka sebagian besar (73.3%) diantaranya hanya mengalami AMS ringan. Sebaliknya, pada kelompok responden yang memiliki tingkat aktivitas fisik rendah maka mayoritas (62.5%) dari mereka mengalami AMS sedang. Hasil uji Chi-square menunjukkan terdapat hubungan bermakna antara tingkat aktivitas fisik dengan AMS pada pendaki gunung (p=0.034). KESIMPULANTerdapat hubungan antara tingkat aktivitas fisik dengan acute mountain sickness pada pendaki gunung.

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