Acute middle ear infection (acute otitis media) in children

Venekamp, Roderick P; Schilder, Anne G. M.; Heuvel, M. van den

doi:10.1136/bmj.m4238

Cited by 17 publications

(21 citation statements)

References 51 publications

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“…The slightly lower sensitivity and specificity to mild CHL are less problematic as this type of hearing loss is mostly due to acute otitis media. Middle ear ventilation problems are common among preschool children and are usually self-limiting (Venekamp et al, 2014). Referring all children with acute CHL for extra examination would result in too many unnecessary diagnostics.…”

Section: Discussionmentioning

confidence: 99%

Language-Independent Hearing Screening – Increasing the Feasibility of a Hearing Screening Self-Test at School-Entry

et al. 2022

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A tablet-based language-independent self-test involving the recognition of ecological sounds in background noise, the Sound Ear Check (SEC), was adapted to make it feasible for young children. Two experiments were conducted. The first experiment investigated the SEC‘s feasibility, as well as its sensitivity and specificity for detecting childhood hearing loss with a monaural adaptive test procedure. In the second experiment, the SEC sounds, noise, and test format were adapted based on the findings of the first experiment. The adaptations were combined with three test procedures, one similar to the one used in Experiment 1, one presenting the sounds dichotically in diotic noise, and one presenting all the sounds with a fixed signal-to-noise ratio and a stopping rule. Results in young children show high sensitivity and specificity to detect different grades of conductive and sensorineural hearing loss (70–90%). When using an adaptive, monaural procedure, the test duration was approximately 6 min, and 17% of the results obtained were unreliable. Adaptive staircase analyses showed that the unreliable results probably occur due to attention/motivation loss. The test duration could be reduced to 3-4 min with adapted test formats without decreasing the test-retest reliability. The unreliable test results could be reduced from 17% to as low as 5%. However, dichotic presentation requires longer training, reducing the dichotic test format‘s feasibility.

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Section: Discussionmentioning

confidence: 99%

Language-Independent Hearing Screening – Increasing the Feasibility of a Hearing Screening Self-Test at School-Entry

et al. 2022

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“…Otitis media can take one of three forms: Acute otitis media (AOM) is characterized by a middle ear effusion and one or more symptoms or indicators of middle ear inflammation [4]. It is the most common bacterial infection, leading to antibiotic use in young children [5].…”

Section: Introductionmentioning

confidence: 99%

Study of gene expression of Cytokine Genes (TLR-4, NOD-2) in patients with Otitis Media in Al-Najaf Governorate, Iraq

Al-Fatlawi,

Al-Ammar,

Al-Manssori

2024

BIO Web Conf.

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The study aimed to evaluate the gene expression of genes (TLR-4,NOD-2) in patients of Otitis media and healthy persons. This finding included 50 samples that collected from healthy subject and 100 samples from a patients suffering from otitis media who attended Al-Sadr Medical City (ENT Department) in Al-Najaf Governorate during the period from February 2022 to June 2022. The samples had an average age ranging from 5 to 70 years. The gene expression of these genes among those suffering from Otitis media and healthy individuals have been investigated in this case-control research. Using a PCR technology. polymerase chain reactions were carried out to amplify each sample for the patient and control groups. The results of the molecular study (gene expression) showed a high significant increase in the level of gene expression in patients for the two genes NOD-2, TLR-4 genes (14.78 ± 2.369, 16.42 ± 3.158), respectively, with a significant difference at P≤0.05. TLR-4, NOD-2 as used as a molecular diagnosis Otitis Media patients.

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“…Otitis media often is the leading cause for antibiotic resistance in the development world. The diagnosis of otitis media should be based on symptoms presence of middle ear effusion, and signs of ear inflammation with a bulging of the tympanic membrane [3].…”

Section: Introductionmentioning

confidence: 99%

The Role Of MicoRNA 146-A (Rs2910164) In Otitis Media Patients In AL-Najaf Provenance/Iraq

Mohammed Hadi Al-fatlawi,

Alammar,

Lafta Al Mansoori

2023

Kufa Jour. Bio.

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The current study aims to shows the relationship between gene polymorphisms (SNP( of miRNA 146-a of patients infected with otitis media. This finding included 50 samples collected from healthy subject and 100 samples from a patienst suffering from otitis media who attended Al-Sadr Medical City (ENT Department) in Al-Najaf Governorate during the period from February 2022 to June 2022. The samples had an average age ranging from 5 to 70 years. Genotyping of miRNA 146-a revealed the presence of three genotypes: GG, CG, and CC, representing (16%, 47%, and 37%) respectively in patients with otitis media, while it was (27%, 18%, and 55%) respectively in healthy subjects. CG was common in patients while GG was more common in healthy subjects. MiRNA as potential biomarker of patients infected with otitis media.

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Acute middle ear infection (acute otitis media) in children

Cited by 17 publications

References 51 publications

Language-Independent Hearing Screening – Increasing the Feasibility of a Hearing Screening Self-Test at School-Entry

Language-Independent Hearing Screening – Increasing the Feasibility of a Hearing Screening Self-Test at School-Entry

Study of gene expression of Cytokine Genes (TLR-4, NOD-2) in patients with Otitis Media in Al-Najaf Governorate, Iraq

The Role Of MicoRNA 146-A (Rs2910164) In Otitis Media Patients In AL-Najaf Provenance/Iraq

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