Acute kidney injury patterns and outcomes in low-risk versus high-risk critically ill patients admitted to the medical intensive care unit

Abstract

Background: Acute kidney injury (AKI) is often one component of multiple organ failure (MOF) in the intensive care unit (ICU Results: Of the 834 critically ill patients, 743 (89%) developed some degree of AKI. Ninetyone percent of the high-risk cohort developed AKI and 87% of the low-risk cohort developed AKI. Patients with AKI had higher mortality at 1 year than patients without AKI (adjusted odds ratio [OR], 2.5; 95% confidence interval, 1.38 to 4.53); P interaction 0.003). Hospital mortality was greater for high-risk patients without AKI than for low-risk patients with AKI.Conclusion: Acute kidney injury occurs at similar frequency in high-and low-risk ICU patients and has significant impact on survival in both groups. Cardiovascular collapse or respiratory failure has greater impact on short term mortality than AKI, but this effect diminishes over time. Conversely, the impact of AKI on mortality increased over time and remained an independent risk factor for mortality.

Outcome of Acute Kidney Injury (AKI) Patients in the Intensive Care Unit of Enam Medical College & Hospital During the Period of July 2018 to May 2019

“…found 67.4% male, Hasmeninan et al31 found 57.6%, Aylward et al39 found 58.9% male, Anaele et al40 found 54.5%, Mahmud et al 37 found 54.23% male, and we found 55.17% were male.In our study, staging of AKI was done by KDIGO classification. We found 27.58% patients were in stage-I, 39.08% as stage-II, 33.33% were found as stage-III.…”