Acute kidney injury in malaria: An update

Chellappan, Anand; Bhadauria, Dharmendra

doi:10.1016/j.cqn.2016.04.004

Cited by 8 publications

(14 citation statements)

References 63 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The patient entered the intensive care unit with criteria of severe malaria given by vasodilated (septic) and hypovolemic shock for the previously described conditions, in addition to Berlin criteria for moderate ARDS (4 quadrant infiltrates, Pa/FiO 2 =112) [15][16][17][18][19], coagulopathy (INR Prolonged, thrombocytopenia) [20], hemodynamic instability, shock Liver (elevated bilirubin) [21] and neurological compromise due to fluctuation of alertness [21]. In other patients, acute renal injury may also occurs [23].…”

Section: Discussionmentioning

confidence: 99%

Plasmodium Falciparum Malaria and Severe Dengue Coinfection in a Pulmonary Tuberculosis Patient: Case Report and Literature Review

Fernando¹,

Camilo²,

Angela³

2018

Arch Clin Med Case Rep

View full text Add to dashboard Cite

Malaria and dengue are the most prevalent vector-borne infections in the world. The clinical manifestations of the two pathologies are similar which may complicate the diagnosis of concurrent dengue and malaria. Coinfection causes a clinical picture of greater severity taking into account the proinflammatory state with capillary leakage and alteration of the glucocalix that is triggered. We present the case of an adult patient with coinfection due to malaria and dengue who is also diagnosed with tuberculosis and required management in the intensive care unit due to multiorgan failure.

show abstract

Section: Discussionmentioning

confidence: 99%

Plasmodium Falciparum Malaria and Severe Dengue Coinfection in a Pulmonary Tuberculosis Patient: Case Report and Literature Review

Fernando¹,

Camilo²,

Angela³

2018

Arch Clin Med Case Rep

View full text Add to dashboard Cite

show abstract

“…Regarding the type of infection, all AKI cases by malaria were observed in the young patients. The impact of AKI during malaria varies in the order of 15 to 48% according to studies (23). This variation could depend on the age of patients and the anti-malarial immunity, which are in their turn influenced by the intensity of malaria transmission (24).…”

Section: Discussionmentioning

confidence: 99%

Comparative study of community acute kidney injury in young patients versus elderly patients in an internal medicine department in Abidjan (Côte d’Ivoire)

Yao¹,

Guei²,

Tia³

et al. 2016

J Renal Inj Prev

View full text Add to dashboard Cite

IntroductionAcute kidney injury (AKI) is characterized by a sudden drop in glomerular filtration rate. It is commonly seen in our medical practice. Its incidence varies from 1.9% to 24.4% depending on the series (1-4). In intensive care units, this incidence is in the order of 20% to 50% (5). The etiologies of AKI vary from one region to the other of the world. In the West countries, septic shock, hyopovolemia, cardiogenic shock and post-operative AKI are the most common in adults (4). In Africa, the Implication for health policy/practice/research/medical education:In our study, we found that regardless of age, infection is the leading cause of acute kidney injury (AKI). Drug-induced AKI is more common in young adults. On the other hand, benign tumor of the urinary tract and malignant hypertension are more found in the elderly. In addition, mortality and non-recovery of renal function are higher in the elderly. The causes of death and the factors associated with mortality and non recovery of renal function differ in both groups. Please cite this paper as: Introduction:Numerous studies have shown that the recovery of renal function was slower and less complete in the elderly patients than in adults. Objectives: To compare the profile of acute kidney injury (AKI) of the young patients with that of the elderly patients. Patients and Methods: This is a prospective study carried out during the period from January 2010 to December 2015 in the department of Nephrology-Internal Medicine of the University hospital of Treichville. The diagnosis of AKI was retained according to Kidney Disease: Improving Global Outcomes (KDIGO) criteria. Results: The mean age of patients was 26.8 ± 6 years in the young and 69.4 ± 7 years in the elderly. The proportion of males was 51.9% (55/106) in the young patients against 77.8% (84/108) in the elderly patients (P = 0.0001). The proportion of hypertension and diabetes in the elderly patients, respectively 30.6% and 36.1% was statistically higher than in the young patients (P = 0.001). However, human immunodeficiency virus (HIV) infection was more prevalent in the young patients (P = 0.0001). Anemia was observed in 84.9% in the young patients against 58.3% in the elderly patients (P = 0.001). It was severe in 34% among the young patients against 15.7% among the elderly patients (P = 0.002). The proportion of drug AKI was 17% in the young patients against 2.8% in the elderly patients (P = 0.0001). Malignant hypertension (P = 0.002) and urinary tract tumors (P = 0.001) were more observed in the elderly patients. Mortality was 31.1% in the young patients against 47.2% in the elderly patients (P = 0.011). Conclusion:The etiologies are the same with different proportions, except malignant hypertension observed only in the elderly patients. Mortality is higher in the elderly patients.

show abstract

“…Histológicamente, la injuria renal aguda producida por P. falciparum es la necrosis tubular aguda (10).…”

Section: Mundial De La Salud (Oms) Para El Año 2010 Para Este Tipo Deunclassified

“…De acuerdo a la literatura, la intervención temprana mejora los resultados renales y extrarrenales para pacientes con lesión renal aguda, esta se ha asociado una mortalidad del 15% en los pacientes con diálisis por hemofiltración en lesión renal aguda por malaria por P. falciparum (18,10).…”

Section: Mundial De La Salud (Oms) Para El Año 2010 Para Este Tipo Deunclassified

“…Se estima un total de 207 millones de casos en el año 2012, de los cuales 627,000 fueron muertes en menores (4)(5)(6)(7)(8)(9)(10). En Colombia, el número de muertes que registró el Departamento Administrativo Nacional de Estadísticas (DANE) durante el periodo de 1999-2009 fue entre 65 y 165 muertes al año y se registraron 150,000 casos anuales por Plasmodium falciparum (5) (Figura 2).…”

Section: Introductionunclassified

See 1 more Smart Citation

Malaria grave en unidad de cuidados intensivos: Reporte de un caso de una especie no endémica en Norte de Santander, Colombia

Ortiz¹,

Urbina-Contreras²,

Lamos-Duarte

et al. 2018

MedUNAB

View full text Add to dashboard Cite

Introducción: La malaria es una enfermedad infecciosa vectorial de predominio en regiones tropicales y subtropicales. Existen 5 serotipos de Plasmodium, en Colombia se encuentran dos serotipos para malaria endémica, P. vivax y P. falciparum. Norte de Santander es una zona endémica para P. vivax. Objetivo: Presentación de un caso de malaria grave importada por P. falciparum, con una breve descripción de los aspectos fisiopatológicos de la malaria grave y los advenimientos de las nuevas terapias antipalúdicas. Presentación del caso: Paciente masculino de 45 años procedente de una región endémica para P. falciparum, que ingresó por cuadro febril inespecífico, trombocitopenia severa, alteración de la función renal y hepática con deterioro de su estado general. Es trasladado a la unidad de cuidados intensivos como urgencia dialítica, se diagnóstica malaria grave por P. falciparum, es tratado con antimaláricos y se reporta posible coinfección para el virus del dengue por inmunoglobulina M positiva (IgM), recibe terapia de reemplazo renal. Se contextualiza bajo un círculo vicioso en la disfunción de órganos, estructurado entre la insuficiencia renal y la insuficiencia respiratoria aguda con incremento de la permeabilidad vascular e hipoxemia refractaria, pese al esfuerzo terapéutico fallece por falla * Médico, especialista en Medicina Interna, especialista en Medicina Crítica y Cuidado Intensivo, especialista en Epidemiología, doctorado en Medicina Traslacional, coordinador

show abstract

Acute kidney injury in malaria: An update

Cited by 8 publications

References 63 publications

Plasmodium Falciparum Malaria and Severe Dengue Coinfection in a Pulmonary Tuberculosis Patient: Case Report and Literature Review

Plasmodium Falciparum Malaria and Severe Dengue Coinfection in a Pulmonary Tuberculosis Patient: Case Report and Literature Review

Comparative study of community acute kidney injury in young patients versus elderly patients in an internal medicine department in Abidjan (Côte d’Ivoire)

Malaria grave en unidad de cuidados intensivos: Reporte de un caso de una especie no endémica en Norte de Santander, Colombia

Contact Info

Product

Resources

About