“… 12 , 13 , 14 More severe manifestations, such as acute kidney injury (AKI), rhabdomyolysis, glomerulonephritis, haemolytic uremic syndrome, and acute renal failure, are often associated to lethal cases of SD. 11 , 15 , 16 Histopathological alterations described in renal tissue include congestion of the glomerular capillary, focal haemorrhage, oedema, inflammatory cell infiltration, hydropic degeneration, formation of micro abscesses, thrombus formation in the glomeruli, glomerular congestion and acute necrosis of proximal and distal tubules. 6 , 17 - 22 On an ultrastructural level, these necrotic tubular cells were shown to be undergoing pyknosis, with dilated endoplasmic reticulum.…”