Acute Hypervolemic Hemodilution to Avoid Blood Transfusion During Major Surgery

Trouwborst, A.; Woerkens, E. C. S. M. Van; Daele, M. Van; Tenbrick, R.

doi:10.1097/00132586-199110000-00043

Cited by 2 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Trouwborst et al 5 had shown that the need of blood transfusion in 16 of their patients who were treated with acute hypervolemic hemodilution using 6% dextran 70 and lactated Ringer solution (1:1 proportion) was reduced without any significant difference in the red blood cell value provided that the bleeding was less than 20% of the blood volume.…”

Section: Departement Of Anesthesiology and Intensive Care Unit Faculmentioning

confidence: 99%

Autologus normovolemic and hypervolemic hemodilution during surgery using 6% dextran 70 and lactated ringer solution: impact on mean arterial pressure, heart rate, hemoglobin and hematocrite (A preliminary study)

Dachlan¹,

Kristanto²,

Suprayogi³

2006

Med J Indones

View full text Add to dashboard Cite

Abstrak Hemodilusi normovolemik autologus (ANH) adalah salah satu cara untuk menghemat darah donor (homologus). (27,3±1,7 vs. 31,5±4,4 pada Ht), dan setelah 20 menit pasca hemodilusi (87,7±7,3 vs. 98,3±6,8 pd MAP) dan (27,4± 1,7 vs. 32,6±4,8 pd Ht) undergoing major surgery. Fourteen (14) women fulfilling the inclusion and exclusion criteria were divided into 2 groups. Seven (7) women received ANH and seven (7) women received HHD method. There were significant statistical differences (P<0.05) between ANH and HHD groups in MAP and Hct after 1 minute (86.3±9.1 vs. 99.1±6.4 on MAP) and (27.3±1.7 vs. 31.5±4.4 on Hct) and after 20 minutes (87.7±7.3 vs. 98.3±6.8 on MAP) and (27.4± 1.7 vs. 3 Abstract Autologous normovolemic hemodilution (ANH) is one of the methods to conserve blood donor (homologous). The decrease in hemoglobin (Hb) due to bleeding in major surgery will be minimized and the hematocrite (Hct) will be adjusted accordingly by this method. However, due to its impractical clinical application, another simpler hemodilution method is used, i.e. hypervolemic hemodilution (HHD), using 6% dextran 70 and lactated Ringer solutions. The aim of this randomized comparative study was to investigate the impacts of both hemodilution methods (ANH and HHD) on mean arterial pressure (MAP), heart rate (HR), hemoglobin (Hb) and hematocrite (Hct) in anesthetized patients

show abstract

Section: Departement Of Anesthesiology and Intensive Care Unit Faculmentioning

confidence: 99%

Autologus normovolemic and hypervolemic hemodilution during surgery using 6% dextran 70 and lactated ringer solution: impact on mean arterial pressure, heart rate, hemoglobin and hematocrite (A preliminary study)

Dachlan¹,

Kristanto²,

Suprayogi³

2006

Med J Indones

View full text Add to dashboard Cite

show abstract

“…Recent meta-analysis concerning ANH in 42 trials has shown only modest benefits from preoperative ANH mainly due to methodological differences and the lack of properly designed controlled trials (Kreimeier and Messmer, 1996;Segal et al, 2004). Some previous clinical trials have used acute preoperative volume expansion without any blood removal and established this relatively new technique as hypervolemic hemodilution (HHD) (Trouwborst et al, 1990a;1990b;Mielke et al, 1997). Very little is known about the efficacy and microhemodynamic effects of HHD compared to ANH.…”

Section: Introductionmentioning

confidence: 99%