Acute Food Protein-Induced Enterocolitis Syndrome

Joshi, Shyam; Nicolaides, Rory; Bird, J. Andrew

doi:10.1007/978-3-030-21229-2_4

Cited by 2 publications

(1 citation statement)

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“…When the reaction is moderate-if the number of vomits is ≥three and is also accompanied by mild lethargy-intravenous fluid therapy should be administered early along with ondansetron. Finally, if the reaction is severe-severe lethargy appears, with hypotonia or cyanosis-in addition to intravenous fluid therapy and ondansetron, a corticosteroid bolus should be administered [20,95,97,98].…”

Section: Therapeutical Perspectivesmentioning

confidence: 99%

Non-IgE-Mediated Gastrointestinal Food Protein-Induced Allergic Disorders. Clinical Perspectives and Analytical Approaches

Zubeldia‐Varela

Barker-Tejeda

Blanco-Pérez

et al. 2021

Foods

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Non-IgE-mediated gastrointestinal food allergy (non-IgE-GI-FA) is the name given to a series of pathologies whose main entities are food protein-induced allergic proctocolitis (FPIAP), food protein-induced enteropathy (FPE), and food protein-induced enterocolitis syndrome (FPIES). These are more uncommon than IgE-mediated food allergies, their mechanisms remain largely unknown, and their diagnosis is mainly done by clinical history, due to the lack of specific biomarkers. In this review, we present the latest advances found in the literature about clinical aspects, the current diagnosis, and treatment options of non-IgE-GI-FAs. We discuss the use of animal models, the analysis of gut microbiota, omics techniques, and fecal proteins with a focus on understanding the pathophysiological mechanisms of these pathologies and obtaining possible diagnostic and/or prognostic biomarkers. Finally, we discuss the unmet needs that researchers should tackle to advance in the knowledge of these barely explored pathologies.

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Section: Therapeutical Perspectivesmentioning

confidence: 99%