Acute exposure to fipronil induces oxidative stress, apoptosis and impairs epithelial homeostasis in the midgut of the stingless bee Partamona helleri Friese (Hymenoptera: Apidae)

Farder-Gomes, Cliver Fernandes; Fernandes, Kenner Morais; Bernardes, Rodrigo Cupertino; Bastos, Daniel Silva Sena; Martins, Gustavo Ferreira; Serrão, José Éduardo

doi:10.1016/j.scitotenv.2021.145679

Cited by 46 publications

(41 citation statements)

References 61 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In SBPH, four caspase genes have been identified, including caspase-Nc, caspase-8, caspase-1a and caspase-1c [36]. Much external stress stimuli, including pesticides, could induce apoptosis in insects [37]. Previous studies showed that a variety of pesticides can induce apoptosis in the salivary glands, midguts, ovaries and other tissues of the bees [37][38][39].…”

Section: Introductionmentioning

confidence: 99%

“…Much external stress stimuli, including pesticides, could induce apoptosis in insects [37]. Previous studies showed that a variety of pesticides can induce apoptosis in the salivary glands, midguts, ovaries and other tissues of the bees [37][38][39]. After exposure to imidacloprid, apoptosis was stimulated in the honey bees [40,41] and bugs [42,43].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Sublethal Effects of Imidacloprid on Fecundity, Apoptosis and Virus Transmission in the Small Brown Planthopper Laodelphax striatellus

Zhang

et al. 2021

Insects

View full text Add to dashboard Cite

Laodelphax striatellus damages plants directly through sucking plant sap and indirectly as a vector of rice stripe virus (RSV), resulting in serious losses of rice yield. It is one of the most destructive insects of rice in East Asia. Insecticides are primarily used for pest management, but the sublethal concentrations of insecticides may benefit several insects. The present research attempted to explore the effects of sublethal concentrations of imidacloprid on the fecundity, apoptosis and RSV transmission in the viruliferous SBPH. The results showed that the fecundity of SBPH was significantly increased after treatment with the LC10 dose of imidacloprid, while the LC30 dose of imidacloprid reduced the fecundity compared with the control. To further investigate the underlying mechanism of increased fecundity after exposure to the LC10 dose of imidacloprid, we examined the expression levels of vitellogenin (Vg), Vg receptor (VgR) and caspases in the ovaries of SBPH, and observed the apoptosis by terminal deoxynucleotidyl transferase (TDT)-mediated dUTP-digoxigenin nick end labeling (TUNEL). qRT-PCR results indicated that the expression levels of Vg, VgR and four caspase genes were all significantly increased by the LC10 dose of imidacloprid, and TUNEL assays suggested that the frequency of apoptosis was significantly higher in the SBPH treated by the LC10 dose of imidacloprid, suggesting a potential correlation between the increased fecundity and the apoptosis of SBPH ovarioles. Additionally, the expression levels of RNA3 and capsid protein (CP) were both increased significantly by the LC10 dose of imidacloprid, whereas were decreased by the LC30 dose of imidacloprid compared to the control. Therefore, this study clarifies the mechanisms of sublethal effects of imidacloprid on viruliferous SBPH and could be used to optimize pest control strategies.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Sublethal Effects of Imidacloprid on Fecundity, Apoptosis and Virus Transmission in the Small Brown Planthopper Laodelphax striatellus

Zhang

et al. 2021

Insects

View full text Add to dashboard Cite

show abstract

“…O rápido aumento da população mundial, saltando de 3,7 bilhões (1970) para 7,8 bilhões (2020), representando um aumento de 211% em 60 anos. Este aumento ao longo das décadas demandou maior produção de alimentos; extração e uso indiscriminado de recursos minerais, principalmente, minérios e água; utilização de combustíveis fósseis e não renováveis; o estilo de vida da sociedade que passou a exigir e denominar como essencial um número crescente de materiais para manter seus padrões de vida, o que vem provocando inúmeros problemas ambientais que ameaçam a sobrevivência de todo o planeta Terra, entre os quais: i) geração de maior quantidade e diversidade de resíduos; ii) poluição dos recursos hídricos; iii) aumento do desmatamento e iv) aumento de atividades industriais e queima de combustíveis fósseis (FARDER-GOMES et al, 2021;GERÉZ et al, 2021;MUKIIBI et al, 2021).…”

Section: Introductionunclassified

“…A associação destes fatores afeta e continuará a afetar cada vez mais, os ecossistemas de diferentes partes do mundo levando a extinção de inúmeras espécies de seres vivos, entre os quais os agentes polinizadores em especial as abelhas (ALGHAMDI et al, 2020;FARDER-GOMES et al, 2021;MUKIIBI et al, 2021). Estas estão presentes no planeta Terra há aproximadamente 60 milhões de anos tendo passado por inúmeras mudanças evolutivas que fizeram destes organismos um dos mais importantes para suporte e manutenção da vida.…”

Section: Introductionunclassified

Reciclar É Transformar: Eletrônica E Robótica Com Resíduos Eletrônicos

Obana¹,

Marinho²,

Sperotto³

et al. 2021

Ciência, Tecnologia E Inovação: A Nova Produção Do Conhecimento 2

View full text Add to dashboard Cite

Direitos para esta edição cedidos à Atena Editora pelos autores. Todo o conteúdo deste livro está licenciado sob uma Licença de Atribuição Creative Commons. Atribuição-Não-Comercial-NãoDerivativos 4.0 Internacional (CC BY-NC-ND 4.0).O conteúdo dos artigos e seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores, inclusive não representam necessariamente a posição oficial da Atena Editora. Permitido o download da obra e o compartilhamento desde que sejam atribuídos créditos aos autores, mas sem a possibilidade de alterá-la de nenhuma forma ou utilizá-la para fins comerciais. Todos os manuscritos foram previamente submetidos à avaliação cega pelos pares, membros do Conselho Editorial desta Editora, tendo sido aprovados para a publicação com base em critérios de neutralidade e imparcialidade acadêmica.A Atena Editora é comprometida em garantir a integridade editorial em todas as etapas do processo de publicação, evitando plágio, dados ou resultados fraudulentos e impedindo que interesses financeiros comprometam os padrões éticos da publicação. Situações suspeitas de má conduta científica serão investigadas sob o mais alto padrão de rigor acadêmico e ético.

show abstract

“…Due to its broad spectrum characteristics, fipronil was widely used in agriculture, horticulture, and animal health to control a wide range of insects, such as lepidopteran and orthopteran pests. Recent studies have reported that fipronil impacts on non-target organisms, such as bees and many aquatic organisms. − Additionally, animal experiments have also revealed that exposure to fipronil at low doses can induce genotoxicity, developmental toxicity, neurotoxicity, and reproductive toxicity. , Fipronil is listed as a WHO class II moderately hazardous pesticide and further as a possible human carcinogen by the USEPA . Fipronil can be metabolized into fipronil desulfinyl, fipronil sulfone, and fipronil sulfide in the environment and biological system, and the toxicity of metabolites to mammals is more or less higher than that of the parent compound .…”

mentioning

confidence: 99%

Generic Enrichment of Organic Contaminants in Human Biomonitoring: Application in Monitoring Early Life Exposures to Fipronil via Breast Milk

Liu

Chen

et al. 2022

Anal. Chem.

View full text Add to dashboard Cite

In human biomonitoring, a high-throughput extraction and enrichment method for multiple types of organic contaminants at the part-per-trillion level is critical yet challenging, especially in the limited sample volume. When large-scale sample analysis is involved, low cost is often what we should consider. We describe a generic and straightforward cold-induced liquid–liquid extraction (CI-LLE) strategy to meet this need. Current methods for extracting and enriching organic contaminants from biological samples often require multistep sample processing, including specially tailoring the extraction solvent or adsorbents. This method uses cold-induced phase separation to achieve the extraction and enrichment of studied organic contaminants by adjusting the proportion of acetonitrile/water mixture, so as to integrate the extraction and enrichment in one step without additional reagents and adsorbents. In this study, fipronil insecticide was used as a representative compound to determine the key parameters of CI-LLE. The optimized CI-LLE procedure allowed simultaneous extraction and enrichment of studied organic contaminants, providing excellent enrichment factors (especially for lipophilic organic contaminants). CI-LLE was further applied in monitoring early life exposures of fipronil in 109 breast milk samples. This study provided baseline data on fipronil levels in breast milk samples from China. For infants, exposure to fipronil is of concern. In summary, CI-LLE provides a feasible solution for a generic, efficient, and low-cost preparation of biological samples and promotes high-throughput batch analysis of organic contaminants for large-scale human biomonitoring.

show abstract

Acute exposure to fipronil induces oxidative stress, apoptosis and impairs epithelial homeostasis in the midgut of the stingless bee Partamona helleri Friese (Hymenoptera: Apidae)

Cited by 46 publications

References 61 publications

Sublethal Effects of Imidacloprid on Fecundity, Apoptosis and Virus Transmission in the Small Brown Planthopper Laodelphax striatellus

Sublethal Effects of Imidacloprid on Fecundity, Apoptosis and Virus Transmission in the Small Brown Planthopper Laodelphax striatellus

Reciclar É Transformar: Eletrônica E Robótica Com Resíduos Eletrônicos

Generic Enrichment of Organic Contaminants in Human Biomonitoring: Application in Monitoring Early Life Exposures to Fipronil via Breast Milk

Contact Info

Product

Resources

About