“…An independent testing at six Washington DC public schools in 2008 showed that 2–41% of sampled tap water has a Pb contamination problem, with the highest lead detected at 1987 μg L −1 , significantly higher than the EPA-recommended maximum level of 20 μg L −1 for schools [ 13 ]. As it is described in literature, in addition to its major neurotoxicity [ 14 , 15 , 16 , 17 , 18 , 19 ] the exposure to Pb has been linked to oxidative stress [ 20 ], cardiovascular toxicity [ 21 ], as well as gut microbiota dysbiosis and hepatic metabolic disorder [ 12 ] in zebrafish. Among the Pb-induced zebrafish neurobehavioral changes identified to date, learning and memory deficits, a decrease in the exploratory activities, altered social and aggressive behavior, color preference or responses to mechanosensory and visual stimuli are included [ 22 , 23 , 24 , 25 , 26 ].…”