Acute Eosinophilic Pneumonia A Summary of 15 Cases and Review of the Literature

Pope-Harman, Amy; Davis, Watson; Allen, Edward D.; Christoforidis, Anthimos J.; Allen, James N.

doi:10.1097/00005792-199611000-00004

Cited by 197 publications

(203 citation statements)

References 47 publications

Supporting

Mentioning

187

Contrasting

Unclassified

Order By: Relevance

“…The rapid response to corticosteroids is also witnessed histologically, and tissue eosinophilia may be markedly diminished to absent in patients with EP if biopsied after the initiation of steroid therapy. [27][28][29]34 ACUTE FIBRINOUS AND ORGANIZING PNEUMONIA Acute fibrinous and organizing pneumonia (AFOP) is characterized by alveolar spaces filled with organizing fibrin balls but lacking the presence of hyaline membrane formation ( Figure 6). Intra-alveolar organizing fibroblastic tissue, some with central fibrinous cores, may be seen but should not constitute the dominant finding, as in cases of OP.…”

Section: Diffuse Alveolar Damagementioning

confidence: 99%

Pulmonary Manifestations of Acute Lung Injury: More Than Just Diffuse Alveolar Damage

Hughes¹,

Beasley

2016

Archives of Pathology &Amp; Laboratory Medicine

131

View full text Add to dashboard Cite

Context.— Acute pulmonary injury may occur as a result of myriad direct or indirect pulmonary insults, often resulting in hypoxemic respiratory failure and clinical acute respiratory distress syndrome. Histologically, most patients will exhibit diffuse alveolar damage on biopsy, but other histologic patterns may be encountered, such as acute eosinophilic pneumonia, acute fibrinous and organizing pneumonia, and diffuse alveolar hemorrhage with capillaritis. Objective.— To review the diagnostic features of various histologic patterns associated with a clinical picture of acute lung injury, and to discuss key features in the differential diagnosis. Data Sources.— The review is drawn from pertinent peer-reviewed literature and the personal experience of the authors. Conclusions.— Acute pulmonary injury is a significant cause of morbidity and mortality. In addition to diffuse alveolar damage, pathologists should be aware of alternate histologic patterns of lung disease that may present with a similar clinical presentation because this may impact treatment decisions and disease outcome.

show abstract

Section: Diffuse Alveolar Damagementioning

confidence: 99%

Pulmonary Manifestations of Acute Lung Injury: More Than Just Diffuse Alveolar Damage

Hughes¹,

Beasley

2016

Archives of Pathology &Amp; Laboratory Medicine

131

View full text Add to dashboard Cite

show abstract

“…Peripheral blood eosinophilia is not a necessary diagnostic feature of AEP (203). AEP is exquisitely responsive to corticosteroid therapy, and though reported treatment regimens are variable in dosage and duration, patients do not generally relapse after completion of therapy (67,147).…”

Section: Aepmentioning

confidence: 99%

Eosinophilic Pneumonias

2012

View full text Add to dashboard Cite

SUMMARY This review starts with discussions of several infectious causes of eosinophilic pneumonia, which are almost exclusively parasitic in nature. Pulmonary infections due specifically to Ascaris , hookworms, Strongyloides , Paragonimus , filariasis, and Toxocara are considered in detail. The discussion then moves to noninfectious causes of eosinophilic pulmonary infiltration, including allergic sensitization to Aspergillus , acute and chronic eosinophilic pneumonias, Churg-Strauss syndrome, hypereosinophilic syndromes, and pulmonary eosinophilia due to exposure to specific medications or toxins.

show abstract

“…Extreme increases in BAL neutrophils are probably caused by infection, or relatively acute and diffuse lung injury. Eosinophil differential cell counts o25% are highly likely to be caused by eosinophilic lung disease, especially eosinophilic pneumonia (EP) if the presentation is acute [25,26]. Increased numbers of mast cells have been associated with HP, drug reactions, sarcoidosis, ILD associated with collagen vascular disease, IPF, COP, EP and malignancy.…”

Section: Bal Characteristics and The Diagnosis Of Specific Types Of Ildmentioning

confidence: 99%

Bronchoalveolar lavage for the evaluation of interstitial lung disease: is it clinically useful?

Meyer¹,

Raghu²

2011

European Respiratory Journal

117

View full text Add to dashboard Cite

Although the application of thoracic high-resolution computed tomography (HRCT) to clinical pulmonology has revolutionised the diagnostic approach to patients with suspected interstitial lung disease (ILD), additional testing is often needed to make a confident ILD diagnosis.Bronchoalveolar lavage (BAL) can play a significant role in making an accurate and confident diagnosis of specific forms of ILD. When BAL is used in conjunction with comprehensive clinical information and HRCT, BAL nucleated immune cell patterns can frequently provide useful information for diagnostic evaluation and lessen the need to proceed to more invasive procedures, such as surgical lung biopsy.Additionally, BAL can identify confounding conditions, such as infection or malignancy. However, BAL technique, and protocols for processing and analysing BAL fluid are critically important for providing useful information.This perspective reviews the current status of using BAL as a diagnostic tool for the diagnosis of ILD.

show abstract

Acute Eosinophilic Pneumonia A Summary of 15 Cases and Review of the Literature

Cited by 197 publications

References 47 publications

Pulmonary Manifestations of Acute Lung Injury: More Than Just Diffuse Alveolar Damage

Pulmonary Manifestations of Acute Lung Injury: More Than Just Diffuse Alveolar Damage

Eosinophilic Pneumonias

Bronchoalveolar lavage for the evaluation of interstitial lung disease: is it clinically useful?

Contact Info

Product

Resources

About