Acute effects of coffee on skin blood flow and microvascular function

Tesselaar, Erik; Dernroth, Dženeta Nezirević; Farnebo, Simon

doi:10.1016/j.mvr.2017.06.006

Cited by 19 publications

(19 citation statements)

References 45 publications

(58 reference statements)

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“…Like coffee, tea also requires hot water for brewing. 35 Increased sympathetic excitability and vasodilatation were thought to be involved in the occurrence and development of flushing and subcutaneous telangiectasia in rosacea. Lukewarm or cool is more common in our country.…”

Section: Discussionmentioning

confidence: 99%

“…33 Studies reported that caffeine played a significant role in sleep deprivation and activation of sympathetic nerves, 34 mediating skin vasodilatation through stimulating iontophoresis of acetylcholine. 35 Increased sympathetic excitability and vasodilatation were thought to be involved in the occurrence and development of flushing and subcutaneous telangiectasia in rosacea. 36 Clinically, a-adrenergic or b-adrenergic receptors blockers contribute to telangiectasia by modulating neuronal dysregulation in rosacea.…”

Section: Discussionmentioning

confidence: 99%

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Relationship between rosacea and dietary factors: A multicenter retrospective case–control survey

Yuan

Huang

Wang

et al. 2019

The Journal of Dermatology

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Although patients with rosacea often consult dermatologists for dietary factors that might be related to their skin disorders, few studies have been conducted to research the relationship between rosacea and dietary factors. The purpose of this study was to evaluate the potential relationship between rosacea and diet among the large Chinese population with rosacea, which would provide dietary guidelines for patients with rosacea. A multicenter case–control study was conducted. The feeding frequency 2 years before the occurrence of rosacea was collected by standardized questionnaires. Multiple logistic regression analysis was used to calculate risks related to the diet. One thousand three hundred and forty‐seven patients with rosacea and 1290 controls were enrolled in our study. We found that high‐frequency intake of fatty food and tea presented a positive correlation with rosacea, while high‐frequency dairy product intake showed significant negative correlation with rosacea. Sweet food, coffee and spicy food appeared to be independent of any subset of rosacea in our study. However, high‐frequency dairy product intake showed a borderline beneficial effect on rosacea severity. We further analyzed the correlation between diet and the subtype of rosacea. We found that high‐frequency fatty intake was associated with erythematotelangiectatic rosacea (ETR) and phymatous rosacea, while high‐frequency tea intake was only associated with ETR. In addition, high‐frequency dairy product intake showed negative correlations with ETR and papulopustular rosacea. Rosacea is associated with some dietary factors, and our study is valuable in establishing dietary guidelines to prevent and improve rosacea.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Relationship between rosacea and dietary factors: A multicenter retrospective case–control survey

Yuan

Huang

Wang

et al. 2019

The Journal of Dermatology

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“…After drinking a single cup of coffee, endothelium-dependent vasodilatation in the skin is acutely enhanced and blood flow in the fingertip is substantially reduced [24]. Intake of caffeine through drinking caffeinated coffee acutely augments microvascular reactivity [25]. It was therefore decided to include caffeine at a dose of 150 mg (2 cups of strong coffee) into this study protocol.…”

Section: Caffeinementioning

confidence: 99%

Assessment of potential drug and substance interference on the performance of the CNOGA TensorTip blood glucose measuring device

Pfützner¹

2019

http://isrctn.com/

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“…Caffeine elevated blood pressure and decreased finger blood flow and at the same time enhanced the PORH of finger blood flow. In contrast, the study by Tesselaar and co-workers reported no change in blood pressure, heart rate, or PORH [22].…”

Section: Introductionmentioning

confidence: 99%

The effect of caffeine on cutaneous postocclusive reactive hyperaemia

et al. 2019

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Background Caffeine is reported to be the most widely used pharmacologically active substance. It causes mental stimulation and increases blood pressure. Acute systolic and diastolic blood pressure response to caffeine attenuates in the course of regular caffeine use; tolerance to cardiovascular responses develops in some people. For some hypertension-prone people coffee ingestion may be harmful, and for others it may be beneficial. The aim of our work was to evaluate the effect of caffeine on postocclusive reactive hyperaemia (PORH), a test of microvascular function, and at the same time to monitor the central effects of caffeine on blood pressure and heart rate. Methods Heart rate, arterial pressure, and cutaneous laser-Doppler (LD) flux were monitored in 32 healthy volunteers (aged 25.2 ± 4.3 years) before and after they ingested 200 mg of caffeine. LD flux was measured on a finger at rest and after the release of an 8-minute occlusion of digital arteries above the place of LD flux measurement. All parameters obtained after the ingestion of caffeine were compared to the values obtained before caffeine and to the values obtained after a placebo. Results We found slightly increased arterial pressure as well as decreased heart rate and resting LD flux (Dunnett’s test, p<0.05) after the ingestion of caffeine. Caffeine significantly reduced the PORH response (Dunnett’s test, p<0.01). The power of the low-frequency oscillations (0.06–0.15 Hz) of LD flux, representing vascular myogenic activity, increased significantly after the ingestion of caffeine at rest and during the PORH response. A correlation was found between the number of cups of coffee regularly consumed and resting LD flux values (R = 0.492, p = 0.00422), peak LD flux values during PORH (R = 0.458, p = 0.00847), and the PORH area (R = 0.506, p = 0.00313) after caffeine consumption. Conclusions From the results, we can conclude that caffeine affects cutaneous microvascular function during rest and during a PORH response, and that it increases blood pressure and decreases heart rate.

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Acute effects of coffee on skin blood flow and microvascular function

Cited by 19 publications

References 45 publications

Relationship between rosacea and dietary factors: A multicenter retrospective case–control survey

Relationship between rosacea and dietary factors: A multicenter retrospective case–control survey

Assessment of potential drug and substance interference on the performance of the CNOGA TensorTip blood glucose measuring device

The effect of caffeine on cutaneous postocclusive reactive hyperaemia

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