Relationship between rosacea and dietary factors: A multicenter retrospective case–control survey

Abstract

Although patients with rosacea often consult dermatologists for dietary factors that might be related to their skin disorders, few studies have been conducted to research the relationship between rosacea and dietary factors. The purpose of this study was to evaluate the potential relationship between rosacea and diet among the large Chinese population with rosacea, which would provide dietary guidelines for patients with rosacea. A multicenter case–control study was conducted. The feeding frequency 2 years before the occurrence of rosacea was collected by standardized questionnaires. Multiple logistic regression analysis was used to calculate risks related to the diet. One thousand three hundred and forty‐seven patients with rosacea and 1290 controls were enrolled in our study. We found that high‐frequency intake of fatty food and tea presented a positive correlation with rosacea, while high‐frequency dairy product intake showed significant negative correlation with rosacea. Sweet food, coffee and spicy food appeared to be independent of any subset of rosacea in our study. However, high‐frequency dairy product intake showed a borderline beneficial effect on rosacea severity. We further analyzed the correlation between diet and the subtype of rosacea. We found that high‐frequency fatty intake was associated with erythematotelangiectatic rosacea (ETR) and phymatous rosacea, while high‐frequency tea intake was only associated with ETR. In addition, high‐frequency dairy product intake showed negative correlations with ETR and papulopustular rosacea. Rosacea is associated with some dietary factors, and our study is valuable in establishing dietary guidelines to prevent and improve rosacea.

Epidemiological features of rosacea in Changsha, China: A population‐based, cross‐sectional study

“…[9][10][11][12] Prevalence differences of rosacea around the world have been mainly attributed to skin phototypes and environmental factors (climate, ultraviolet [UV] exposure and lifestyle). 13 Regardless of racial differences in prevalence, sampling methodology and case criteria may also influence prevalence findings. Our study involved residents from communities of different socioeconomic strata to account for differences among participants and to give more representative results.…”

Relationship between rosacea and sleep

“…Besides the genetic background, other factors, including Demodex colonization, microbial stimuli, ultraviolet radiation, heat, dietary factors and stress, are considered to be related to this condition 13,14 . Other behavioral factors, including anxiety and depression, are found to be associated with rosacea 15 …”

Coffee and Skin: What do We Know About it?

“…34,35 On the other hand, there has been a growing debate about whether the caffeine or the temperature of the coffee is the actual culprit for exacerbation of rosacea. [34][35][36] The fact that increased risk of rosacea is also linked with caffeine containing beverages that are lukewarm or cool in temperature, has brought the idea of the association of caffeine and rosacea is not only heat related. 36 Moreover, paradoxically, in a recent study it has been shown that increased caffeine intake from coffee is conversely associated with the risk of rosacea in women.…”

“…[34][35][36] The fact that increased risk of rosacea is also linked with caffeine containing beverages that are lukewarm or cool in temperature, has brought the idea of the association of caffeine and rosacea is not only heat related. 36 Moreover, paradoxically, in a recent study it has been shown that increased caffeine intake from coffee is conversely associated with the risk of rosacea in women. 37 Caffeine is a methylxanthine, which increases intracellular calcium stimulating the production of nitric oxide (NO).…”

“…Increased sympathetic excitability and vasodilatation are assumed to be implicated in the development of flushing and subcutaneous telangiectasia in rosacea. [34][35][36]39 The pathogenesis of rosacea still remains unclear. Abnormal neurovascular signaling is presumed to be one of the key constituents of the pathogenesis.…”