Acute effects of coffee consumption on self-reported gastrointestinal symptoms, blood pressure and stress indices in healthy individuals

Abstract

BackgroundIt has been suggested that coffee may affect the gut-brain axis with conflicting outcomes. Moreover, there is insufficient evidence to determine whether the type or temperature of coffee consumed will have a different impact on the gut-brain axis. The purpose of this study was to investigate the effects of acute coffee consumption on the following: 1. self-reported GI symptoms and salivary gastrin, 2. stress indices [salivary cortisol and alpha-amylase (sAA)] and psychometric measures, and 3. blood pressure (BP), in healthy, daily coffee consuming individuals in non-stressful conditions.MethodsThis was a randomized, double blind, crossover clinical trial, in which 40 healthy individuals (20 men, 20 women), 20–55 years of age, randomly consumed four 200 ml coffee beverages containing 160 mg caffeine (hot and cold instant coffee, cold espresso, hot filtered coffee), 1 week apart. Salivary samples and psychometric questionnaires were collected at baseline and post-coffee consumption at 15,30, and 60 min for salivary gastrin and sAA measurements and at 60,120, and 180 min for cortisol measurements. BP was measured at beginning and end of each intervention. ClinicalTrials.gov ID: NCT02253628 ResultsCoffee consumption significantly increased sAA activity (P = 0.041), with significant differences only between cold instant and filter coffee at 15 and 30 min post-consumption (P < 0.05). Coffee temporarily increased salivary gastrin, without differences between coffee types. Coffee did not affect salivary cortisol or self-reported anxiety levels. Coffee consumption significantly increased BP, within the healthy physiological levels, in a gender specific manner at the end of the experimental periods, without differences between coffee types.ConclusionAcute coffee consumption in non-stressful conditions activated sAA and BP but not salivary cortisol, indicating activation of the sympathetic nervous system. Post-coffee sAA increase without a concomitant cortisol increase may also indicate that coffee may have some anti-stress properties.

Risk Factors of Acid Peptic Disease Among Adults Attending the General Medicine Outpatient Department of a Tertiary Care Institution in South India- A Cross Sectional Study

“…(20) In a study by Emelia Papakonstantinon, Ionna Kachribari did not find any significant association between coffee consumption and acid peptic disease. (21) In our study, we could not find out any relationship between non vegetarian diet and acid peptic disease. (21) But in a comparative study by Jung J G, Kang H W et al among Buddhist priests and general population established a significant association between non vegetarianism and acid peptic disease.…”

“…(21) In our study, we could not find out any relationship between non vegetarian diet and acid peptic disease. (21) But in a comparative study by Jung J G, Kang H W et al among Buddhist priests and general population established a significant association between non vegetarianism and acid peptic disease. (22) Similarly a study by Syed Faisal Zaidihad established a relationship between a non-vegetarian diet and acid peptic disease.…”

Non-linear analysis of heart rate variability for evaluating the acute effects of caffeinated beverages in young adults

“…These drinks contain 3784 mg, 1514 mg, and 404 mg caffeine, respectively. 17,18 Data acquisition Electrocardiogram recordings were obtained from the participants for 5 minutes in rest and sitting position. Disposable Ag-AgCl electrodes were placed following the Einthoven triangle configuration.…”

Negative Air Pressure on Wet Cupping in Decreasing Blood Pressures in Hypertensive Patients

“…Subjects (44.4%) in the control group and subjects (27.8%) in the intervention group had a habit of drinking coffee. Papakonstantinou et al (2016) reported coffee consumption significantly increased BP 3 hours post-consumption without differences between coffee types, and temporary hypertensive coffee effect occurred even after small doses of consumed caffeine (80 mg/day). The type of coffee consumed may have a different impact on BP suggesting that boiled coffee may cause a higher increase in BP compared to filtered coffee, after daily consumption of large coffee doses (>5 cups) for several days or weeks.…”