Acute Depletion of the Hormonal-Iodine Stores From the Thyroid Gland After Birth in Lambs

Slebodzinski, A B

doi:10.1677/joe.0.0530195

Cited by 8 publications

(5 citation statements)

References 6 publications

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“…The data on serum were analyzed at 0, 6, 12 and24 h. Time The concentration of glucose, the principal serum energy source for the newborn pig (Mount 1969), increased in the serum of both groups of pigs (P < 0.05) after birth ( (Swiatek et al 1968). Furthermore, Stanton (Slebodzinski 1972 Serum Ts concentrations of warmfarrowed piglets were similar to those reported by Parker et al (1980). While serum T, levels were similar (P > 0.05) in both treatments at birth and24 h, levels of T3 were higher (P < 0.05) at l2h in the cold-farrowed piglets (Table 4) For personal use only.…”

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confidence: 73%

Serum Concentration Changes in Protein, Glucose, Urea, Thyroxine and Triiodothyronine and Thermostability of Neonatal Pigs Farrowed at 25 and 10 °c

Parker¹,

Williams²,

Aherne³

et al. 1980

Can. J. Anim. Sci.

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A. 1980. Serum concentration changes in protein, glucose, urea, thyroxine and triiodothyronine and thermostability of neonatal pigs farrowed at 25 and 10"C. Can. J. Anim. On day 108 of gestation, l6 sows were moved to farrowing crates in either a warm ( l 0 sows; 25.C) or cold (six sows; 10"c) room. Piglet blood samples were drawn by vena cava puncture at birth, 6, 12 and24hof age, and body weights, rectal temperatules and thermostability of piglets were recorded. Serum samples were analyzed for total protein, glucose, urea, thyroxine (Ta), triiodothyronine (T3), and cortisol (24 h only).Piglet mortality was 31 .3Vo and 6.4Vo for pigs farrowed in the cold oI waffn envrronments, respectively. Piglets that died weighed less (P < 0.05) than those that survived. Total serum protein increased (P < 0.05) after birth from 3 g/dl to more thanT gldL; however, thi. incr.a." occurred later in the pigs farrowed at l0'C. Serum glucosi of pigs farrowed in the cold was higher (P < 0.05) than that for pigs ar25"C.S.rum u.ea *as elevated (P < 0.01) by 6.2mgldLtn the cold-farrowed piglets. Serum Ta was lower (P < 0.05) at birth, 6 and 12 h for the 10"C pigs but was similar for both groups by 24 h. Serum T3 increased (P < 0.05) after birth and was sustained to l2 h in i|etb'cpigtetsbutnotinrheothers. At24h,serumcortisolwassimilar(P>0.05)in both groupi (10.3 +-1.02 p.eldL). Body temperatures were lower (P < 0.05) in cold-farrowed piglets, but both groups lost body heat at similar rates' Au 108" jour de leur gestation, l6 truies ont 6t6 mises en cases de maternit6 dans une pibce chaude, 25"C, 10 truies, ou froide, 10'C, 6 truies' Des prises de sang par ponction de

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supporting

confidence: 73%

Serum Concentration Changes in Protein, Glucose, Urea, Thyroxine and Triiodothyronine and Thermostability of Neonatal Pigs Farrowed at 25 and 10 °c

Parker¹,

Williams²,

Aherne³

et al. 1980

Can. J. Anim. Sci.

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“…Unlike the lamb, in which the thyroglobulin iodine content is high [Slebodzinski, 1972], in the pig it varies markedly at birth which may be an indication of a large variability in the functional capacity of the pituitary-thyroid system existing in this spe cies.…”

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confidence: 95%

Sequential Observation of Changes in Thyroxine, Triiodothyronine and Reverse Triiodothyronine during the Postnatal Adaptation of the Pig

1981

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Principal serum iodothyronines, T₄, T₃ and rT₃, have been simultaneously measured by a specific radioimmunoassay in piglets kept for sequential observation with the mother from 1 to 21 days of age. During several hours postnatally, a high concentration of the hormone was noted as a result of an enhanced secretory activity of the thyroid gland. Later, a progressive decrease with a nadir at about day 3 was observed, followed by a second rise in the hormone level. Changes in T₃ and rT₃ levels from birth to the end of the 1st week, paralleled those for T₄. The T₃:rT₃ ratio of about 2 during the 1st week fell to about 1.5 during the 3rd week as a result of the progressive increase in rT₃ and decrease in T₃ concentrations. The T₄:rT₃ ratio fell with the progressing age to the level observed in post-weaned pigs. At birth, the newborn pig seems to possess a low capability of 5-deiodinase enzyme system thus the converting enzymes first work towards T₄–T₃ conversion while T₄–rT₃-converting ability progressively increases with age. The role of this variability for the neonatal thermogenic stability is discussed.

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“…In fact, neonatal plasma T3 and fT4 rises followed that of TSH concentrations, lasting for 24 h after birth, but T4 levels declined before (after 2 h of life), when TSH levels were still elevated (Cabello and Wrutniak, 1990). Therefore, the thyroid gland seems unable to respond, in terms of T4 secretion, to a prolonged stimulation by TSH, probably because a depletion of hormonal stores in the gland occurs during the first minutes of life (Slebodzinski, 1972). It is likely that during the first hours of life the thyroid gland can respond to other stimulating factors: small increases of plasma TH followed exogenous prolactin administration in neonatal lamb, but not in growing lambs and ewes (Peeters et al, 1992).…”

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Thyroid hormones in small ruminants: effects of endogenous, environmental and nutritional factors

Todini

2007

Animal

193

142

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Appropriate thyroid gland function and thyroid hormone activity are considered crucial to sustain the productive performance in domestic animals (growth, milk or hair fibre production). Changes of blood thyroid hormone concentrations are an indirect measure of the changes in thyroid gland activity and circulating thyroid hormones can be considered as indicators of the metabolic and nutritional status of the animals. Thyroid hormones play a pivotal role in the mechanisms permitting the animals to live and breed in the surrounding environment. Variations in hormone bioactivity allow the animals to adapt their metabolic balance to different environmental conditions, changes in nutrient requirements and availability, and to homeorhetic changes during different physiological stages. This is particularly important in the free-ranging and grazing animals, such as traditionally reared small ruminants, whose main physiological functions (feed intake, reproduction, hair growth) are markedly seasonal. Many investigations dealt with the involvement of thyroid hormones in the expression of endogenous seasonal rhythms, such as reproduction and hair growth cycles in fibre-producing (wool, mohair, cashmere) sheep and goats. Important knowledge about the pattern of thyroid hormone metabolism and their role in ontogenetic development has been obtained from studies in the ovine foetus and in the newborn. Many endogenous (breed, age, gender, physiological state) and environmental factors (climate, season, with a primary role of nutrition) are able to affect thyroid activity and hormone concentrations in blood, acting at the level of hypothalamus, pituitary and/or thyroid gland, as well as on peripheral monodeiodination. Knowledge on such topics mirror physiological changes and possibly allows the monitoring and manipulation of thyroid physiology, in order to improve animal health, welfare and production.Keywords: goats, nutrition, seasons, sheep, thyroid hormones IntroductionAppropriate thyroid gland function and activity of thyroid hormones (TH) are considered crucial to sustain the productive performance in domestic animals (growth, milk, hair fibre production) and circulating TH can be considered as indicators of the metabolic and nutritional status of the animals (Riis and Madsen, 1985;Todini et al., 2007). Changes of blood TH concentrations are an indirect measure of the changes in thyroid gland activity. Many papers report marked seasonal variation in thyroid activity and in blood TH concentration. These hormone variations are particularly important in the free-ranging and grazing animals, whose main physiological functions (feed intake, reproduction, hair growth) are markedly seasonal. This is the case of small ruminants traditionally reared. Such variations in hormone concentration, in fact, allow the animals to adapt their metabolic balance to different environmental conditions, variations in nutrient requirements and availability, and to homeoretic changes during different physiological stages.The present paper aims to re...

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Acute Depletion of the Hormonal-Iodine Stores From the Thyroid Gland After Birth in Lambs

Cited by 8 publications

References 6 publications

Serum Concentration Changes in Protein, Glucose, Urea, Thyroxine and Triiodothyronine and Thermostability of Neonatal Pigs Farrowed at 25 and 10 °c

Serum Concentration Changes in Protein, Glucose, Urea, Thyroxine and Triiodothyronine and Thermostability of Neonatal Pigs Farrowed at 25 and 10 °c

Sequential Observation of Changes in Thyroxine, Triiodothyronine and Reverse Triiodothyronine during the Postnatal Adaptation of the Pig

Thyroid hormones in small ruminants: effects of endogenous, environmental and nutritional factors

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