2016
DOI: 10.1016/j.nurpra.2015.10.013
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Acute Compartment Syndrome of the Lower Leg: A Review

Abstract: Acute compartment syndrome (ACS) of the lower leg is a time-sensitive orthopedic emergency that relies heavily on precise clinical findings. Late findings of ACS can lead to limb amputation, contractures, paralysis, multiorgan failure, and death. Hallmark symptoms of ACS include the 6 P’s: pain, poikilothermia, pallor, paresthesia, pulselessness, and paralysis. Suspicion of ACS is confirmed by measurement of intracompartmental pressure of the affected compartment. The definitive treatment of ACS is timely fasc… Show more

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Cited by 52 publications
(41 citation statements)
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“…Rhabdomyolysis, a serious condition caused by muscle injury, may occur if the diagnosis of ACS is not made in time for urgent fasciotomy. The presence of high CK levels in the blood may indicate severe muscle damage or ischemia and may cause acute renal failure [ 3 , 5 , 9 ]. In the absence of clinical signs, raised CK levels could indicate an unsuspected ACS [ 6 ]; however, because rhabdomyolysis can lead to acute renal failure, and can be life-threatening [ 9 ], elevated CK levels should not be relied on for an early diagnosis of ACS [ 2 4 , 6 , 7 ], and creatinine clearance and plasma creatinine are late-stage markers of kidney damage that has already occurred [ 29 ].…”
Section: Discussionmentioning
confidence: 99%
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“…Rhabdomyolysis, a serious condition caused by muscle injury, may occur if the diagnosis of ACS is not made in time for urgent fasciotomy. The presence of high CK levels in the blood may indicate severe muscle damage or ischemia and may cause acute renal failure [ 3 , 5 , 9 ]. In the absence of clinical signs, raised CK levels could indicate an unsuspected ACS [ 6 ]; however, because rhabdomyolysis can lead to acute renal failure, and can be life-threatening [ 9 ], elevated CK levels should not be relied on for an early diagnosis of ACS [ 2 4 , 6 , 7 ], and creatinine clearance and plasma creatinine are late-stage markers of kidney damage that has already occurred [ 29 ].…”
Section: Discussionmentioning
confidence: 99%
“…The symptoms of ACS include swelling, pain on passive stretch, pain out of proportion to the injury, paresthesia, and paresis or paralysis [ 4 ]; however, it is important to note that not all characteristic of ACS may be present [ 5 ]. Clinical signs such as pallor, reduced capillary return, and absent peripheral pulses are late signs of ACS, and therefore the presence of distal pulses should not be relied on to exclude a diagnosis of ACS [ 4 ].…”
Section: Introductionmentioning
confidence: 99%
“…Patients most often present with symptoms of aching or burning pain that may be disproportionate to the injury, which can occasionally have associated paresthesia. Cardinal physical exam signs are an associated tense compartment and motor deficits in the affected limb [31,32]. Measurement of ICP in the suspected compartment is used as a supplemental diagnostic tool for cases that are not diagnosed clinically.…”
Section: Discussionmentioning
confidence: 99%
“…Poikilothermia, also known as “6Ps”, is a fundamental symptom of acute limb ischemia (ALI) ; however, this condition cannot be assessed objectively. Herein, we present a case of a 27‐year‐old man whose right foot was diagnosed with ALI due to insertion of a cannula into the right femoral artery for veno‐arterial extracorporeal membrane oxygenation (ECMO).…”
Section: Case Presentationmentioning
confidence: 99%