Acute cigarette smoking reduces vasodilative effect induced by sympathetic block in dogs

Abstract

Sympathetic block induces a significant increase of peripheral blood flow, but smoking produces a significant decrease in the blood flow in the SGB-induced dilated vessels.

Comparison of 2% Mepivacaine, Clipping, and Radiofrequency Thermocoagulation for Duration and Magnitude of Action in Peripheral Arterial Blood Flow Induced by Sympathetic Block in Anesthetized Dogs

“…In our previous study using the same animal model, cervicothoracic sympathetic block by a local anesthetic induced a decrease in peripheral arterial blood flow in the lower extremities remaining innervated because of compensatory vasoconstriction. 13 In conclusion, thoracic sympathetic block by clipping induces a significant increase of peripheral arterial blood flow comparable to 2% mepivacaine, but the magnitude of blood flow induced by clipping is lower than that of radiofrequency thermocoagulation. Therefore, the sympathetic blocking potency of clipping may be less than that of radiofrequency thermocoagulation.…”

Comparison of 0.25% Levobupivacaine, 0.25% Bupivacaine, and 0.125% Bupivacaine for Duration and Magnitude of Action in Peripheral Arterial Blood Flow Induced by Sympathetic Block in Dogs

“…[16][17][18] We also used 1.0 mL of levobupivacaine or bupivacaine for sympathetic block in the present study. However, our model of experimental sympathetic block in dogs is different from that of a clinical setting.…”