Acute bacterial meningitis among children &amp;lt;5 years of age in Oman: a retrospective study during 2000-2005

Dash, Nihar Ranjan; Panigrahi, D; Khusaiby, S. Al; Awaidy, Salah Al; Bawikar, Shyam

doi:10.3855/t2.2.112

Cited by 13 publications

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“…For bacterial meningitis S.pneumoniae was isolated from (10) cases (18.18 %) , this so close to [15] and [13] who found this bacteria caused bacterial meningitis in (15 ,16.7) % respectively of cases. In bacterial meningitis the median age was (130.75) months within range (1-144) month as shown in table (1), the predominance was in age group (1-20) months which appear as (42) (76.36 %).…”

Section: -Diagnosis Of Bacterial Meningitissupporting

confidence: 65%

Occurrence of Pneumococcal Meningitis in Iraq

Al-Banae,

Habib,

Al-Khurki

2012

Baghdad Sci.J

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This study focuses on the relative frequency of Streptococcus pneumoniae in children with culture-proven bacterial meningitis. The epidemiology has been investigated with clinical and laboratory findings in The Central Public Health Laboratory, Iraq from April to September, 2010. From (138) samples , (55) cases (39.85 %) were diagnosed by physician as bacterial meningitis, (23) cases (16.66 %) as viral menginitis , (18) cases (13.04 %) as different medical cases (e.g febrile convulsion , meningoencephalitis , epilepsy …etc) and (42) cases (30.43 %) as unidentified medical cases. For bacterial meningitis S.pneumoniae was isolated from (10) cases (18.18 %) only. The median age for bacterial meningitis was (130.75) month and the predominance was in the age group (1-20) months which appear as (42) cases (76.36 %) . Fever was the frequent presenting symptoms in (49) cases (89.09 %) , followed vomiting in (34) cases (61.81 %) , then irritability and seizures in (29 ,25) cases (52.72 , 45.45) % respectively . In bacterial meningitis , the mean for glucose and protein levels was (44 and 65) (mg/dl) respectively.

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Section: -Diagnosis Of Bacterial Meningitissupporting

confidence: 65%

Occurrence of Pneumococcal Meningitis in Iraq

Al-Banae,

Habib,

Al-Khurki

2012

Baghdad Sci.J

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“…Cerebrospinal meningitis (CSM) is a major cause of morbidity and mortality in many parts of the world [1-3]. Despite the progress being made in treating the condition, the mortality rates continue to be high, ranging between 2% and 30% globally [4-6].…”

Section: Introductionmentioning

confidence: 99%

Aetiological agents of cerebrospinal meningitis: a retrospective study from a teaching hospital in Ghana

Owusu

Nguah

Boaitey

et al. 2012

Annals of Clinical Microbiology and Antimicrobials

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AbstractsBackgroundMeningitis is an important cause of morbidity and mortality in low-resource settings. In sub-Saharan Africa, the meningitis belt has been characterized by particularly high and seasonal incidences of bacterial meningitis extending throughout life. Despite the progress being made in treating the condition, the mortality rates continue to be high, ranging between 2% and 30% globally. In Ghana, the mortality rate of meningitis has been estimated to range from 36% to 50%. However little information is available on the pathogens contributing to meningitis and their antimicrobial susceptibilities. Updated information is essential to adjust the recommendations for empirical treatment or prevention of meningitis which could have immense implications for local and global health.MethodsWe retrospectively reviewed laboratory records of all patients suspected of bacterial meningitis who underwent a lumbar puncture from January 1, 2008 to December 31, 2010. Data were retrieved from laboratory record books and double entered into a Microsoft® excel spreadsheet.ResultsRecords of 4,955 cerebrospinal fluid samples were analysed. Of these, 163 (3.3%, 95%CI: 2.8% to 3.8%) were confirmed meningitis and 106 (2.1%, 95%CI: 1.7% to 2.6%) were probable meningitis cases. Confirmed meningitis cases were made up of 117 (71.8%) culture positive bacteria, 19 (11.7%) culture positive Cryptococcus neoformans and 27(16.6%) Gram positive bacteria with negative culture. The most prevalent bacteria was Streptococcus pneumoniae 91 (77.7%), followed by E.coli 4 (3.4%), Salmonella species 4 (3.4%), Neisseria meningitidis 3 (2.5%), Pseudomonas species 3(2.5%) and others. Pneumococcal isolates susceptibility to penicillin, chloramphenicol and ceftriaxone were 98.9% (95%CI: 94.0% to 100.0%), 83.0% (95%CI: 73.4% to 90.1%) and 100.0% (95%CI: 95.8% to 100.0%) respectively.ConclusionStreptococcus pneumoniae is an important cause of meningitis among all age groups and its susceptibility to penicillin and ceftriaxone still remains very high. Ghanaians of all ages and possibly other developing countries in the meningitis belt could benefit from the use of the pneumococcal vaccine. Other bacterial and fungal pathogens should also be considered in the management of patients presenting with meningitis.

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“…If the meninges of the spinal cord are involved, the disease state is termed Cerebrospinal Meningitis (CSM). Meningitis contributes significantly to morbidity and mortality in many regions of the world [1, 2]. There have been advancements in the diagnosis and treatment of meningitis over the years.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the enhanced meningitis surveillance system, Yendi municipality, northern Ghana, 2010–2015

Kaburi¹,

Kubio²,

Kenu³

et al. 2017

BMC Infect Dis

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BackgroundMeningitis is the inflammation of the meninges of the brain and or spinal cord. Global mortality rates vary from 2% to 30%. Epidemic meningitis remains a public health concern along the meningitis belt of Africa. Despite the operation of an enhanced meningitis surveillance system in Ghana, institutional mortality rates are estimated to range from 36% to 50%. In 2014, Yendi recorded 83 confirmed cases; with focal epidemics in some sub-municipals. We evaluated the system over a five-year period to find out whether it was achieving its objectives of systematic collection and analyses of data for the prevention or early detection of meningitis epidemics.MethodsWe used cross-sectional design. Both qualitative and quantitative data from Yendi Municipality between January 2010 and December 2015 were collected and analyzed. The updated guidelines for evaluating surveillance systems from Centers for Disease Control and Prevention were used. Content analysis was performed on the responses of key informants. Surveillance data was analyzed using MS-Excel.ResultsFifteen healthcare workers were interviewed. For the period under evaluation, the annual incidence of meningitis ranged from 1.6/100,000 in 2012 to 62.6/100,000 in 2014. The average case fatality rate for the period was 8.3%. The system was sensitive, representative, and acceptable. The predictive value positive was 100% from 2010 to 2014 and 63.3% in 2015. Data quality was good, but timeliness of reporting was poor.ConclusionsThe enhanced meningitis surveillance system in Yendi Municipality is achieving most of its objectives. However, financial constraints and poor personnel motivation pose threats to the sustainability of the system.Electronic supplementary materialThe online version of this article (doi:10.1186/s12879-017-2410-0) contains supplementary material, which is available to authorized users.

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Acute bacterial meningitis among children <5 years of age in Oman: a retrospective study during 2000-2005

Cited by 13 publications

References 0 publications

Occurrence of Pneumococcal Meningitis in Iraq

Occurrence of Pneumococcal Meningitis in Iraq

Aetiological agents of cerebrospinal meningitis: a retrospective study from a teaching hospital in Ghana

Evaluation of the enhanced meningitis surveillance system, Yendi municipality, northern Ghana, 2010–2015

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