Acute Appendicitis Associated With Typhoid Fever: A Case Report and Review of Literature

Abstract

Introduction: Appendicitis could be a rare complication of Salmonella Typhi infection. Case Presentation: we present a 13-year-old girl with typhoid fever with histology-proven acute appendicitis as a rare complication of Salmonella Typhi infection. The patient was admitted to the hospital with the chief complaints of fever, abdominal pain, diarrhea, and vomiting for more than one week. A brief review of relevant literature was also performed to explore more this rare cause of a common emergency surgical procedure. Conclusions: In all cases with typhoid fever with persistent diarrhea and vomiting, localized abdominal pain, probable acute appendicitis should be considered as an important complication.

Extensively Drug-Resistant Salmonella typhi Infection: From Pill to Scalpel

“…Acute appendicitis is a common surgical emergency, but it is rare to get acute appendicitis due to S. typhi. Cases of acute appendicitis due to drug-sensitive S. typhi in children and adults have been reported in the past [ 4 - 5 ]. With its emergence in 2018 in Hyderabad, Pakistan, 14,360 cases of extensively drug-resistant Salmonella typhi (XDR S. typhi) have been reported by the National Institute of Health (NIH), Pakistan [ 6 ].…”