Acupuncture and Electroauriculotherapy Treatment for Infertility

Cavalla, Hilda

doi:10.1089/acu.2009.0715

Cited by 3 publications

(2 citation statements)

References 6 publications

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“…In recent years, acupuncture is more and more popular in the management of subfertility, but its effectiveness has remained controversial [1]. Some studies showed that acupuncture was significant in improving IVF outcomes [2,3,4]. The specific rationales were displayed as follows.…”

Section: Introductionmentioning

confidence: 99%

“…Second, acupuncture may enhance blood flow of the uterus and reduce uterine artery blood flow impedance [7]. Third, acupuncture treatment may enhance the hormonal balance of the embryo implantation stage of IVF in the treatment of infertility [4]. Another study also showed that acupuncture may promote the release of neurotransmitters, thereby mediating the development of hormones [8].…”

Section: Introductionmentioning

confidence: 99%

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The Role of Acupuncture in in vitro Fertilization: A Systematic Review and Meta-Analysis

Shen¹,

Shu³

et al. 2014

Gynecol Obstet Invest

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Background/Aims: In recent years, acupuncture has become more and more popular in the management of subfertility. The aim of this study was to evaluate the impact of acupuncture during in vitro fertilization (IVF) treatment on the outcomes of clinical pregnancy in published randomized studies. Methods: This is a systematic review and meta-analysis. Data sources used were MEDLINE, Embase, Web of Knowledge and the Chinese Biomedical Database. Results: There was no statistically significant difference between the acupuncture group and no acupuncture (intervention) controls around the time of embryo transfer (ET; risk ratio, RR, 1.24, 95% confidence interval, CI, 1.02-1.50) or in unblinded trials, trials blinded to physicians and double-blind trials (95% CI 1.26-1.88, 0.82-1.33 and 0.89-1.25, respectively). This was also the case when comparing acupuncture with sham acupuncture controls around the time of ET (RR, 1.03, 95% CI 0.87-1.22) or when restricting to unblinded trials, trials blinded to physicians and double-blind trials (95% CI 0.80-2.02, 0.82-1.18 and 0.77-1.17, respectively). There was a statistically significant difference when performed at 30 min after ET and implantation phase (RR 1.76, 95% CI 1.22-2.55). There was also a statistically significant difference when performed at follicle phase and 25 min before and after ET (RR 1.56, 95% CI 1.04-2.33). Conclusion: Our study showed that acupuncture did not significantly improve the IVF clinical pregnancy rate when performed only at the time of ET, while we found pooled benefit of acupuncture for IVF when performed at follicle phase and 25 min before and after ET, as well as 30 min after ET and implantation phase.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The Role of Acupuncture in in vitro Fertilization: A Systematic Review and Meta-Analysis

Shen¹,

Shu³

et al. 2014

Gynecol Obstet Invest

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Effect of Chinese Herbal Medicine on Female Infertility

Jiang¹,

Li²

2017

OGIJ

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Due to the lack of a perfectly satisfactory outcome from standard medical treatment, patients are looking to alternative therapies to improve their results. Acupuncture has been proven by many different studies from both laboratory and clinic to play an important role in supporting infertility treatment [13-15]. Chinese Herbal Medicine is an integral part of Traditional Chinese Medicine, in which acupuncture, diet, exercise (Taiji)and Qigong are involved together as a whole system of health maintenance. Do they play an important role in supporting infertility treatment? As a traditional medical system, how can this system of TCM be used to give the best result or infertility treatment? In this chapter we perform a thorough review of papers.

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An Overview of Systematic Reviews of Acupuncture for Infertile Women Undergoing in vitro Fertilization and Embryo Transfer

Wang

Wei

et al. 2021

Front. Public Health

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Background: Currently, more and more subfertility couples are opting for combined acupuncture to improve the success rate of in vitro fertilization and embryo transfer (IVF-ET). However, the efficacy and safety of acupuncture in IVF-ET is still highly controversial.Objectives: The purpose of this overview is to summarize evidence of essential outcomes of systematic reviews (SRs) of acupuncture in IVF-ET and evaluate their methodological quality.Methods: We conducted a comprehensive literature search for relevant SRs in eight databases from inception to July 31, 2020, without language restriction. We evaluated the methodological quality of the included SRs by using A Measurement Tool to Assess Systematic Reviews 2 (AMSTAR-2), which was the latest available assessment tool. The Risk of Bias in Systematic Review (ROBIS) tool was used to assess the risk of bias in SRs. We assessed the Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) score to determine the strength of evidence. We excluded the overlapping randomized controlled trials (RCTs) and performed a re-meta-analysis of the primary RCTs.Results: This review included 312 original RCT studies and 65,388 participants. By using AMSTAR-2, we found that the methodological quality of 16 SRs was critically low, because they had more than one critical weakness. Our reviews showed that although the GRADE for quality of evidence profile was suboptimal, acupuncture seemed to be beneficial in increasing the pregnancy rate. Our re-meta-analysis suggested that acupuncture was superior to sham acupuncture in improving the clinical pregnancy rate (CPR) of IVF-ET with substantial heterogeneity (RR = 1.31, 95% CI: 1.13–1.52, p = 0.0004, I2 = 66%). No statistical difference was observed regarding the outcomes of live birth rate (LBR), ongoing pregnancy rate (OPR), biochemical pregnancy rate (BPR), and miscarriage rate (MR) between two groups. When compared with no adjunctive treatment groups, acupuncture improved CPR (RR = 1. 25, 95% CI: 1.11–1.42, p = 0.0003) and OPR (RR = 1. 38, 95% CI: 1.04–1.83, p = 0.03). Acupuncture was more superior than no adjunctive treatment in reducing MR (OR = 1.42, 95% CI: 1.03–1.95, p = 0.03) and BPR (RR = 1.19, 95% CI: 1.02–1.37, p = 0.02).Conclusions: Although the evidence of acupuncture in IVF-ET is insufficient, acupuncture appears to be beneficial to increase the clinical pregnancy rate in women undergoing IVF-ET. However, there are severe heterogeneity and methodological quality defects, which limit the reliability of results. Further, high-quality primary studies are still needed.

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Acupuncture and Electroauriculotherapy Treatment for Infertility

Cited by 3 publications

References 6 publications

The Role of Acupuncture in in vitro Fertilization: A Systematic Review and Meta-Analysis

The Role of Acupuncture in in vitro Fertilization: A Systematic Review and Meta-Analysis

Effect of Chinese Herbal Medicine on Female Infertility

An Overview of Systematic Reviews of Acupuncture for Infertile Women Undergoing in vitro Fertilization and Embryo Transfer

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