Acupuncture: a new method to treat tic disorders in children

Geng, Junze; Xu, Jingyu; Wang, XiaoGe; Liu, YanQi; Cui, YangNing; Li, Xinmin

doi:10.53388/tmr20220127259

Cited by 5 publications

(4 citation statements)

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“…Auriculotherapy, on the other hand, uses an acupuncture microsystem that acts on the ear by stimulating reflex points to the symptoms felt by the person, making it a simple technique with few adverse effects [19][20][21][22] . Two aspects of ear acupuncture are described: one is related to Traditional Chinese Medicine (TCM), which assumes communication between the internal organs and the auricular pavilion via meridians, channels, and/or innervation of the vagus nerve, and the French one by Paul Nogier, who describes the ear as a map resembling that of an inverted foetus, corresponding to the reflex points of the organs of interest [23][24][25] .…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of Tea Made from <i>Cissampelos sympodialis</i> Leaves in the Treatment of Anxiety and Depression: A Controlled Clinical Trial

Barros Mangueira,

Medeiros Negreiros,

Soares Aragão

et al. 2024

JNR

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The species Cissampelos sympodialis Eichl. (CsE) is popularly used for its anti-inflammatory, bronchodilator and anti-allergiceffects. In preclinical studies, the plant has shown anxiolytic and antidepressant properties, which necessitated a controlledclinical trial to verify its effects in humans. A quasi-randomized study was developed in which the volunteers were divided intothree groups: CsE leaves tea (n = 21), auriculotherapy (n = 20) and no intervention (n = 19). The participants in the three groupsreceived weekly sachets of powdered dried leaves of CsE for tea preparation or auriculotherapy or did not receive intervention,respectively. At the beginning and end of the 5-week follow-up, the volunteers completed the following questionnaires: STAI-S,STAI-T, BDI and BAI. The phytochemical analysis of the sachet containing the powdered dried CsE leaves showed the presenceof alkaloids, steroids, tannins and flavonoids. In addition, the chromatographic analysis of CsE leaves identified the presence of7 chemical substances, for instance Malic Acid, α-L-Mannofuranose and Myo-Inositol. The STAI-S, STAI-T, BDI and BAI responsesshowed that the groups using tea or auriculotherapy showed significant reductions in mean scores in the two-way repeatedmeasures analysis of variance. In the no-intervention group, no significant differences were found on any scale. Applying the post-hoc test, the influence of the group on the initial or final variances of the STAI-S (p = 0.004), STAI-T (p = 0.005), BDI (p < 0.0005)and BAI (p = 0.011) data were tested, highlighting that the tea and auriculotherapy led to the decrease in the questionnairescores post-treatment. The tea of leaves of CsE proved, in this study, to be effective in decreasing the scores of STAI-S, STAI-T,BDI and BAI and could represent a new perspective of complementary treatment for the symptoms of anxiety and depression.

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Section: Introductionmentioning

confidence: 99%

Effectiveness of Tea Made from <i>Cissampelos sympodialis</i> Leaves in the Treatment of Anxiety and Depression: A Controlled Clinical Trial

Barros Mangueira,

Medeiros Negreiros,

Soares Aragão

et al. 2024

JNR

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“…The existing treatment methods mainly include non-drug treatment and drug treatment Non-drug treatment mainly includes comprehensive behavioral intervention for tics (CBIT), psychoeducation and supportive therapy (PST), 5 acupuncture, etc. 6 However, because the above treatment methods need the guidance of professionally trained doctors and the active cooperation of patients (more suitable for patients over 9 years old), the beneficiary population is relatively small. At present, the drugs widely used in the treatment of TS mainly include dopamine modulating agents, alpha-2-adrenergic agonists, GABAergic medicines, and other atypical neuroleptics; the development of the above drugs is mainly based on the main etiology of TS, neurotransmitter disorder, especially the disinhibition of the Cortical-Striatum-Thalamus-Cortical Circuits.…”

Section: Introductionmentioning

confidence: 99%

Potential relationship between Tourette syndrome and gut microbiome

Geng¹,

Liu²,

Xu³

et al. 2023

Jornal de Pediatria

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“…Acupuncture, especially electroacupuncture or scalp acupuncture alone, demonstrates a positive effect in terms of total clinical effectiveness rate, the incidence of adverse events, and recurrence. Currently, common methods of acupuncture treatment for tic disorders include traditional Chinese medicine acupuncture, electroacupuncture, scalp acupuncture, and auricular acupuncture ( 14 ). However, these methods have some disadvantages, such as long-time needle retention, challenges in electric current control, or the necessity for the child to take the initiative.…”

Section: Introductionmentioning

confidence: 99%

Mechanism of Qihuang needle therapy in the management of tic disorders: a clinical trial protocol

Tang

et al. 2023

Front. Neurol.

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BackgroundQihuang needle therapy is a newly developed acupuncture therapy to treat tic disorders in clinical practice. However, the mechanism to reduce tic severity remains unknown. Changes in intestinal flora and circulation metabolites are perhaps the potential pathogenesis of tic disorders. As a result, we present a protocol for a controlled clinical trial using multi-omics analysis to probe the mechanism of the Qihuang needle in managing tic disorders.MethodsThis is a matched-pairs design, controlled, clinical trial for patients with tic disorders. Participants will be allocated to either an experimental group or a healthy control group. The main acupoints are Baihui (GV20), Yintang (EX-HN3), and Jueyinshu (BL14). The experimental group will receive Qihuang needle therapy for a month, while the control group will receive no interventions.Expected outcomesThe change in the severity of the tic disorder is set as the main outcome. Secondary outcomes include gastrointestinal severity index and recurrence rate, which will be calculated after a 12-week follow-up. Gut microbiota, measured by 16S rRNA gene sequencing; serum metabolomics, assessed via LC/MS; and serum zonulin, assessed by enzyme-linked immunosorbent assay (ELISA), will be used as biological specimen analysis outcomes. The present study will investigate the possible interactions between intestinal flora and serum metabolites and the improvement of clinical profiles, which may elucidate the mechanism of Qihuang needle therapy for tic disorders.Trial registrationThis trial is registered at the Chinese Clinical Trial Registry (http://www.chictr.org.cn/). Registration number: ChiCTR2200057723, Date: 2022-04-14.

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Acupuncture: a new method to treat tic disorders in children

Cited by 5 publications

References 0 publications

Effectiveness of Tea Made from <i>Cissampelos sympodialis</i> Leaves in the Treatment of Anxiety and Depression: A Controlled Clinical Trial

Effectiveness of Tea Made from <i>Cissampelos sympodialis</i> Leaves in the Treatment of Anxiety and Depression: A Controlled Clinical Trial

Potential relationship between Tourette syndrome and gut microbiome

Mechanism of Qihuang needle therapy in the management of tic disorders: a clinical trial protocol

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